Zobrazeno 1 - 10
of 118
pro vyhledávání: '"COVID-19 Genomics UK (COG-UK) consortium"'
Autor:
QinQin Yu, Joao A Ascensao, Takashi Okada, COVID-19 Genomics UK (COG-UK) Consortium, Olivia Boyd, Erik Volz, Oskar Hallatschek
Publikováno v:
PLoS Pathogens, Vol 20, Iss 4, p e1012090 (2024)
Genetic drift in infectious disease transmission results from randomness of transmission and host recovery or death. The strength of genetic drift for SARS-CoV-2 transmission is expected to be high due to high levels of superspreading, and this is ex
Externí odkaz:
https://doaj.org/article/54499924c55b4d6fbf11f47395fc77d6
Autor:
Helen R Fryer, Tanya Golubchik, Matthew Hall, Christophe Fraser, Robert Hinch, Luca Ferretti, Laura Thomson, Anel Nurtay, Lorenzo Pellis, Thomas House, George MacIntyre-Cockett, Amy Trebes, David Buck, Paolo Piazza, Angie Green, Lorne J Lonie, Darren Smith, Matthew Bashton, Matthew Crown, Andrew Nelson, Clare M McCann, Mohammed Adnan Tariq, Claire J Elstob, Rui Nunes Dos Santos, Zack Richards, Xin Xhang, Joseph Hawley, Mark R Lee, Priscilla Carrillo-Barragan, Isobel Chapman, Sarah Harthern-Flint, COVID-19 Genomics UK (COG-UK) consortium, David Bonsall, Katrina A Lythgoe
Publikováno v:
PLoS Pathogens, Vol 19, Iss 10, p e1011706 (2023)
[This corrects the article DOI: 10.1371/journal.ppat.1011461.].
Externí odkaz:
https://doaj.org/article/34a741634d014981b3874599a314d832
Autor:
Helen R Fryer, Tanya Golubchik, Matthew Hall, Christophe Fraser, Robert Hinch, Luca Ferretti, Laura Thomson, Anel Nurtay, Lorenzo Pellis, Thomas House, George MacIntyre-Cockett, Amy Trebes, David Buck, Paolo Piazza, Angie Green, Lorne J Lonie, Darren Smith, Matthew Bashton, Matthew Crown, Andrew Nelson, Clare M McCann, Mohammed Adnan Tariq, Claire J Elstob, Rui Nunes Dos Santos, Zack Richards, Xin Xhang, Joseph Hawley, Mark R Lee, Priscilla Carrillo-Barragan, Isobel Chapman, Sarah Harthern-Flint, COVID-19 Genomics UK (COG-UK) consortium, David Bonsall, Katrina A Lythgoe
Publikováno v:
PLoS Pathogens, Vol 19, Iss 8, p e1011461 (2023)
In this study, we evaluated the impact of viral variant, in addition to other variables, on within-host viral burden, by analysing cycle threshold (Ct) values derived from nose and throat swabs, collected as part of the UK COVID-19 Infection Survey.
Externí odkaz:
https://doaj.org/article/88e48725cc0d4fceb3aa9902b74fd193
Autor:
David J Pascall, Elen Vink, Rachel Blacow, Naomi Bulteel, Alasdair Campbell, Robyn Campbell, Sarah Clifford, Chris Davis, Ana da Silva Filipe, Noha El Sakka, Ludmila Fjodorova, Ruth Forrest, Emily Goldstein, Rory Gunson, John Haughney, Matthew T G Holden, Patrick Honour, Joseph Hughes, Edward James, Tim Lewis, Samantha Lycett, Oscar MacLean, Martin McHugh, Guy Mollett, Yusuke Onishi, Ben Parcell, Surajit Ray, David L Robertson, Sharif Shabaan, James G Shepherd, Katherine Smollett, Kate Templeton, Elizabeth Wastnedge, Craig Wilkie, Thomas Williams, Emma C Thomson, COVID-19 Genomics UK (COG-UK) Consortium
Publikováno v:
PLoS ONE, Vol 18, Iss 4, p e0284187 (2023)
ObjectivesThe SARS-CoV-2 Alpha variant was associated with increased transmission relative to other variants present at the time of its emergence and several studies have shown an association between Alpha variant infection and increased hospitalisat
Externí odkaz:
https://doaj.org/article/5ecaa821cd60430382854e3d5351fc4e
Autor:
Max Foxley-Marrable, Leon D'Cruz, Paul Meredith, Sharon Glaysher, Angela H Beckett, Salman Goudarzi, Christopher Fearn, Kate F Cook, Katie F Loveson, Hannah Dent, Hannah Paul, Scott Elliott, Sarah Wyllie, Allyson Lloyd, Kelly Bicknell, Sally Lumley, James McNicholas, David Prytherch, COVID-19 Genomics UK (COG-UK) consortium, Andrew Lundgren, Or Graur, Anoop J Chauhan, Samuel C Robson
Publikováno v:
PLoS ONE, Vol 18, Iss 3, p e0283447 (2023)
Throughout the COVID-19 pandemic, valuable datasets have been collected on the effects of the virus SARS-CoV-2. In this study, we combined whole genome sequencing data with clinical data (including clinical outcomes, demographics, comorbidity, treatm
Externí odkaz:
https://doaj.org/article/67d0fea1984a4bc7aa69d8ab028fd92b
Autor:
Áine O'Toole, Verity Hill, Ben Jackson, Rebecca Dewar, Nikita Sahadeo, Rachel Colquhoun, Stefan Rooke, J T McCrone, Kate Duggan, Martin P McHugh, Samuel M Nicholls, Radoslaw Poplawski, COVID-19 Genomics UK (COG-UK) Consortium, COVID-19 Impact Project (Trinidad & Tobago Group), David Aanensen, Matt Holden, Tom Connor, Nick Loman, Ian Goodfellow, Christine V F Carrington, Kate Templeton, Andrew Rambaut
Publikováno v:
PLOS Global Public Health, Vol 2, Iss 12, p e0000704 (2022)
The scale of data produced during the SARS-CoV-2 pandemic has been unprecedented, with more than 13 million sequences shared publicly at the time of writing. This wealth of sequence data provides important context for interpreting local outbreaks. Ho
Externí odkaz:
https://doaj.org/article/08383bf31a2d4c478b05e017f0b61534
Reduced neutralisation of the Delta (B.1.617.2) SARS-CoV-2 variant of concern following vaccination.
Autor:
Chris Davis, Nicola Logan, Grace Tyson, Richard Orton, William T Harvey, Jonathan S Perkins, Guy Mollett, Rachel M Blacow, COVID-19 Genomics UK (COG-UK) Consortium, Thomas P Peacock, Wendy S Barclay, Peter Cherepanov, Massimo Palmarini, Pablo R Murcia, Arvind H Patel, David L Robertson, John Haughney, Emma C Thomson, Brian J Willett, COVID-19 DeplOyed VaccinE (DOVE) Cohort Study investigators
Publikováno v:
PLoS Pathogens, Vol 17, Iss 12, p e1010022 (2021)
Vaccines are proving to be highly effective in controlling hospitalisation and deaths associated with SARS-CoV-2 infection but the emergence of viral variants with novel antigenic profiles threatens to diminish their efficacy. Assessment of the abili
Externí odkaz:
https://doaj.org/article/0eb1aae545894621899f5ddd6e562753
Autor:
Shay Leary, Silvana Gaudieri, Matthew Parker, Abha Chopra, Ian James, Suman Pakala, Eric Alves, Mina John, Benjamin Lindsey, Alexander Keeley, Sarah Rowland-Jones, Maurice Swanson, David Ostrov, Jodi Bubenik, Suman Das, John Sidney, Alessandro Sette, COVID-19 Genomics UK (COG-UK) consortium, Thushan de Silva, Elizabeth Phillips, Simon Mallal
Publikováno v:
Pathogens and Immunity, Vol 6, Iss 2 (2021)
Background: Genetic variations across the SARS-CoV-2 genome may influence transmissibility of the virus and the host’s anti-viral immune response, in turn affecting the frequency of variants over time. In this study, we examined the adjacent amino
Externí odkaz:
https://doaj.org/article/0e6cb380ed5c485f8c8e44524bb4614b
Autor:
Helen Harper, Amanda Burridge, Mark Winfield, Adam Finn, Andrew Davidson, David Matthews, Stephanie Hutchings, Barry Vipond, Nisha Jain, COVID-19 Genomics UK (COG-UK) Consortium, Keith Edwards, Gary Barker
Publikováno v:
PLoS ONE, Vol 16, Iss 2, p e0243185 (2021)
Tracking genetic variations from positive SARS-CoV-2 samples yields crucial information about the number of variants circulating in an outbreak and the possible lines of transmission but sequencing every positive SARS-CoV-2 sample would be prohibitiv
Externí odkaz:
https://doaj.org/article/593eab5eb7f44ded88636344488e8b3e
Autor:
Pascall, David J, Vink, Elen, Blacow, Rachel, Bulteel, Naomi, Campbell, Alasdair, Campbell, Robyn, Clifford, Sarah, Davis, Chris, da Silva Filipe, Ana, El Sakka, Noha, Fjodorova, Ludmila, Forrest, Ruth, Goldstein, Emily, Gunson, Rory, Haughney, John, Holden, Matthew TG, Honour, Patrick, Hughes, Joseph, James, Edward, Lewis, Tim, MacLean, Oscar, McHugh, Martin, Mollett, Guy, Nyberg, Tommy, Onishi, Yusuke, Parcell, Ben, Ray, Surajit, Robertson, David L, Seaman, Shaun R, Shabaan, Sharif, Shepherd, James G, Smollett, Katherine, Templeton, Kate, Wastnedge, Elizabeth, Wilkie, Craig, Williams, Thomas, COVID-19 Genomics UK (COG-UK) consortium, Thomson, Emma C
OBJECTIVES: To determine how the intrinsic severity of successively dominant SARS-CoV-2 variants changed over the course of the pandemic. METHODS: A retrospective cohort analysis in the NHS Greater Glasgow and Clyde (NHS GGC) Health Board. All sequen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b135991df5f4171052b3dd2293dbf2be
https://www.repository.cam.ac.uk/handle/1810/350825
https://www.repository.cam.ac.uk/handle/1810/350825