Zobrazeno 1 - 10
of 28
pro vyhledávání: '"COVID-19/immunology"'
Publikováno v:
Acta Médica Portuguesa, Vol 37, Iss 3 (2024)
N/a.
Externí odkaz:
https://doaj.org/article/324e7975806047e2b5ee7a50ec2bf3cc
Autor:
Jia Zhe Su, Michael H. Malim, Daniel Cox, Neophytos Kouphou, Sam Acors, Carl Graham, Ana Maria Ortega-Prieto, Luke B Snell, Cassandra Fairhead, Stuart J. D. Neil, Liane Dupont, Helena Winstone, Thomas Lechmere, Rui Pedro Galão, Sadie R. Hallett, Gaia Nebbia, Isabella Huettner, Nathalia Almeida, Marie Jose Lista, Adela Alcolea-Medina, Thomas J. A. Maguire, Suzanne Pickering, Manu Shankar-Hari, Rahul Batra, Jonathan D. Edgeworth, Jose M. Jimenez-Guardeño, Katie J. Doores, Ruth E Dickenson, Jeffrey Seow, Themoula Charalampous, Harry Wilson, Blair Merrick
Publikováno v:
Nature Microbiology
Dupont, L, Snell, L B, Graham, C, Seow, J, Merrick, B, Lechmere, T, Maguire, T J A, Hallett, S R, Pickering, S, Charalampous, T, Alcolea-Medina, A, Huettner, I, Jimenez-Guardeño, J M, Acors, S, Almeida, N, Cox, D, Dickenson, R E, Galao, R P, Kouphou, N, Lista, M J, Ortega-Prieto, A M, Wilson, H, Winstone, H, Fairhead, C, Su, J Z, Nebbia, G, Batra, R, Neil, S, Shankar-Hari, M, Edgeworth, J D, Malim, M H & Doores, K J 2021, ' Neutralizing antibody activity in convalescent sera from infection in humans with SARS-CoV-2 and variants of concern ', Nature Microbiology, vol. 6, no. 11, pp. 1433-1442 . https://doi.org/10.1038/s41564-021-00974-0
Dupont, L, Snell, L B, Graham, C, Seow, J, Merrick, B, Lechmere, T, Maguire, T J A, Hallett, S R, Pickering, S, Charalampous, T, Alcolea-Medina, A, Huettner, I, Jimenez-Guardeño, J M, Acors, S, Almeida, N, Cox, D, Dickenson, R E, Galao, R P, Kouphou, N, Lista, M J, Ortega-Prieto, A M, Wilson, H, Winstone, H, Fairhead, C, Su, J Z, Nebbia, G, Batra, R, Neil, S, Shankar-Hari, M, Edgeworth, J D, Malim, M H & Doores, K J 2021, ' Neutralizing antibody activity in convalescent sera from infection in humans with SARS-CoV-2 and variants of concern ', Nature Microbiology, vol. 6, no. 11, pp. 1433-1442 . https://doi.org/10.1038/s41564-021-00974-0
COVID-19 vaccine design and vaccination rollout need to take into account a detailed understanding of antibody durability and cross-neutralizing potential against SARS-CoV-2 and emerging variants of concern (VOCs). Analyses of convalescent sera provi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5faf396a883d2efccb60cc07135362b
http://europepmc.org/articles/PMC8556155
http://europepmc.org/articles/PMC8556155
Autor:
Tanya Golubchik, Anthony C. Gordon, Rutger J. Ploeg, Ullrich Leuscher, Wendy Slack, Pat Tsang, Manu Shankar-Hari, David K. Menon, Paul R Mouncey, Sarah Williams, Lise J Estcourt, Sheba Ziyenge, Farah Al-Beidh, Heli Harvala, Nick A Ciccone, Peter Simmonds, David J. Roberts, Jeremy Ratcliff, Kathryn M Rowan, Abigail Lamikanra, Jennifer Rynne, Amy Evans, Dung Nguyen, Aislinn Jennings, Matthew Fish, Emma Laing, David Bonsall, Marta S Oliveira
Publikováno v:
2021, ' Virological Characterization of Critically Ill Patients With COVID-19 in the United Kingdom : Interactions of Viral Load, Antibody Status, and B.1.1.7 Infection ', The Journal of Infectious Diseases, vol. 224, no. 4, pp. 595-605 . https://doi.org/10.1093/infdis/jiab283
BackgroundConvalescent plasma containing neutralizing antibody to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is under investigation for coronavirus disease 2019 (COVID-19) treatment. We report diverse virological characteristics of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3935a99113299cb16abdecddfb35876e
https://doi.org/10.1093/infdis/jiab283
https://doi.org/10.1093/infdis/jiab283
Systems serology detects functionally distinct coronavirus antibody features in children and elderly
Autor:
Allen C. Cheng, Francesca L Mordant, Katherine Kedzierska, Keith J. Chappell, Daniel Watterson, Brendon Y. Chua, Hannah G. Kelly, Suzanne K. Shoffner, Jane Crowe, Carolien E. van de Sandt, Melissa M. Lemke, Naphak Modhiran, Bruce D. Wines, Fatima Amanat, Thi H. O. Nguyen, Adam K. Wheatley, Marios Koutsakos, Wen Shi Lee, Hyon-Xhi Tan, Luca Hensen, Kelly B. Arnold, David C. Jackson, Paul R. Young, Amy W. Chung, Paul V. Licciardi, Katie L. Flanagan, Shidan Tosif, Samantha K Davis, Louise C. Rowntree, Chinn Yi Wong, Jennifer A Juno, Stephen J. Kent, Nigel W Crawford, P. Mark Hogarth, Philip Sutton, Melanie R Neeland, Robyn Esterbauer, Kevin J. Selva, Florian Krammer, Denise L. Doolan, Christina Lee
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Nature Communications, 12(1):2037
Nature Communications
Nature communications, 12(1). Nature Publishing Group
Nature Communications, 12(1):2037
Nature Communications
Nature communications, 12(1). Nature Publishing Group
The hallmarks of COVID-19 are higher pathogenicity and mortality in the elderly compared to children. Examining baseline SARS-CoV-2 cross-reactive immunological responses, induced by circulating human coronaviruses (hCoVs), is needed to understand su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce261502baebcd38da10bcf6b67f9fcd
https://doaj.org/article/b3735969bc2442d3bede1a835ba02866
https://doaj.org/article/b3735969bc2442d3bede1a835ba02866
Autor:
Claus Bistrup, Ulrik Stenz Justesen, Rune Micha Pedersen, Thøger Gorm Jensen, Line L. Bang, Thomas Emil Andersen, Helene Kierkegaard, Ditte Sandfeld Tornby, Isik Somuncu Johansen, Anna Nilsson
Publikováno v:
Kidney International
Pedersen, R M, Bang, L L, Tornby, D S, Kierkegaard, H, Nilsson, A C, Johansen, I S, Bistrup, C, Jensen, T G, Justesen, U S & Andersen, T E 2021, ' The SARS-CoV-2–neutralizing capacity of kidney transplant recipients 4 weeks after receiving a second dose of the BNT162b2 vaccine ', Kidney International, vol. 100, no. 5, pp. 1129-1131 . https://doi.org/10.1016/j.kint.2021.09.006
Pedersen, R M, Bang, L L, Tornby, D S, Kierkegaard, H, Nilsson, A C, Johansen, I S, Bistrup, C, Jensen, T G, Justesen, U S & Andersen, T E 2021, ' The SARS-CoV-2–neutralizing capacity of kidney transplant recipients 4 weeks after receiving a second dose of the BNT162b2 vaccine ', Kidney International, vol. 100, no. 5, pp. 1129-1131 . https://doi.org/10.1016/j.kint.2021.09.006
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d221a9f29944aa52ae0b314ebbf14a63
https://doi.org/10.1016/j.kint.2021.09.006
https://doi.org/10.1016/j.kint.2021.09.006
Autor:
Crommelin, Daan J A, Volkin, David B, Hoogendoorn, Karin H, Lubiniecki, Anthony S, Jiskoot, Wim, Afd Pharmaceutics, Pharmaceutics
Publikováno v:
Journal of Pharmaceutical Sciences, 110(2), 627. John Wiley and Sons Inc.
Journal of Pharmaceutical Sciences
Journal of Pharmaceutical Sciences, 110(2), 627-634. ELSEVIER SCIENCE INC
Journal of Pharmaceutical Sciences
Journal of Pharmaceutical Sciences, 110(2), 627-634. ELSEVIER SCIENCE INC
Once Covid-19 vaccines become available, 5-10 billion vaccine doses should be globally distributed, stored and administered. In this commentary, we discuss how this enormous challenge could be addressed for viral vector-based Covid-19 vaccines by lea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe583dd69c79521def0e1b8a0547e571
https://doi.org/10.1016/j.xphs.2020.11.015
https://doi.org/10.1016/j.xphs.2020.11.015
Autor:
Renée M van der Sluis, Lamin B Cham, Albert Gris‐Oliver, Kristine R Gammelgaard, Jesper G Pedersen, Manja Idorn, Ulvi Ahmadov, Sabina Sanches Hernandez, Ena Cémalovic, Stine H Godsk, Jacob Thyrsted, Jesper D Gunst, Silke D Nielsen, Janni J Jørgensen, Tobias Wang Bjerg, Anders Laustsen, Line S Reinert, David Olagnier, Rasmus O Bak, Mads Kjolby, Christian K Holm, Martin Tolstrup, Søren R Paludan, Lasse S Kristensen, Ole S Søgaard, Martin R Jakobsen
Publikováno v:
van der Sluis, R M, Cham, L B, Gris-Oliver, A, Gammelgaard, K R, Pedersen, J G, Idorn, M, Ahmadov, U, Sanches Hernandez, S, Cémalovic, E, Godsk, S H, Thyrsted, J, Gunst, J D, Nielsen, S D, Jørgensen, J J, Wang Bjerg, T, Laustsen, A, Reinert, L S, Olagnier, D, Bak, R O, Kjolby, M, Holm, C K, Tolstrup, M, Paludan, S R, Kristensen, L S, Søgaard, O S & Jakobsen, M R 2022, ' TLR2 and TLR7 mediate distinct immunopathological and antiviral plasmacytoid dendritic cell responses to SARS-CoV-2 infection ', The EMBO Journal, pp. e109622 . https://doi.org/10.15252/embj.2021109622
van der Sluis, R M, Cham, L B, Gris-Oliver, A, Gammelgaard, K R, Pedersen, J G, Idorn, M, Ahmadov, U, Hernandez, S S, Cémalovic, E, Godsk, S H, Thyrsted, J, Gunst, J D, Nielsen, S D, Jørgensen, J J, Bjerg, T W, Laustsen, A, Reinert, L S, Olagnier, D, Bak, R O, Kjolby, M, Holm, C K, Tolstrup, M, Paludan, S R, Kristensen, L S, Søgaard, O S & Jakobsen, M R 2022, ' TLR2 and TLR7 mediate distinct immunopathological and antiviral plasmacytoid dendritic cell responses to SARS-CoV-2 infection ', EMBO Journal, vol. 41, no. 10, e109622 . https://doi.org/10.15252/embj.2021109622
van der Sluis, R M, Cham, L B, Gris-Oliver, A, Gammelgaard, K R, Pedersen, J G, Idorn, M, Ahmadov, U, Hernandez, S S, Cémalovic, E, Godsk, S H, Thyrsted, J, Gunst, J D, Nielsen, S D, Jørgensen, J J, Bjerg, T W, Laustsen, A, Reinert, L S, Olagnier, D, Bak, R O, Kjolby, M, Holm, C K, Tolstrup, M, Paludan, S R, Kristensen, L S, Søgaard, O S & Jakobsen, M R 2022, ' TLR2 and TLR7 mediate distinct immunopathological and antiviral plasmacytoid dendritic cell responses to SARS-CoV-2 infection ', EMBO Journal, vol. 41, no. 10, e109622 . https://doi.org/10.15252/embj.2021109622
Understanding the molecular pathways driving the acute antiviral and inflammatory response to SARS-CoV-2 infection is critical for developing treatments for severe COVID-19. Here, we find decreasing number of circulating plasmacytoid dendritic cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1fd30736af2a491a85fdee063fc4b93
https://doi.org/10.15252/embj.2021109622
https://doi.org/10.15252/embj.2021109622
Autor:
Angela Genchi, Aurora Semerano, Ghil Schwarz, Beatrice Dell’Acqua, Giorgia Serena Gullotta, Michela Sampaolo, Enzo Boeri, Angelo Quattrini, Francesca Sanvito, Susanna Diamanti, Andrea Bergamaschi, Stefano Grassi, Paola Podini, Pietro Panni, Caterina Michelozzi, Franco Simionato, Francesco Scomazzoni, Paolo Remida, Luca Valvassori, Andrea Falini, Carlo Ferrarese, Patrik Michel, Guillaume Saliou, Steven Hajdu, Simone Beretta, Luisa Roveri, Massimo Filippi, Davide Strambo, Gianvito Martino, Marco Bacigaluppi
Publikováno v:
Acta Neuropathologica Communications
Acta neuropathologica communications, vol. 10, no. 1, pp. 14
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-13 (2022)
Acta neuropathologica communications, vol. 10, no. 1, pp. 14
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-13 (2022)
Coronavirus disease 2019 (COVID-19) is associated with an increased risk of thrombotic events. Ischemic stroke in COVID-19 patients entails high severity and mortality rates. Here we aimed to analyze cerebral thrombi of COVID-19 patients with large v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::021f006ea1f12848d828feb76b14eed1
Autor:
Christopher M Rice, Philip Lewis, Fernando M Ponce-Garcia, Willem Gibbs, Sarah Groves, Drinalda Cela, Fergus Hamilton, David Arnold, Catherine Hyams, Elizabeth Oliver, Rachael Barr, Anu Goenka, Andrew Davidson, Linda Wooldridge, Adam Finn, Laura Rivino, Borko Amulic
Publikováno v:
Rice, C M, Lewis, P, Ponce-Garcia, F M, Gibbs, W, Groves, S, Cela, D, Hamilton, F, Arnold, D, Hyams, C, Oliver, E, Barr, R, Goenka, A, Davidson, A, Wooldridge, L, Finn, A, Rivino, L & Amulic, B 2022, ' Hyperactive immature state and differential CXCR2 expression of neutrophils in severe COVID-19 ', Life Science Alliance, vol. 6, no. 2, e202201658, pp. 1-13 . https://doi.org/10.26508/lsa.202201658
Neutrophils are vital in defence against pathogens, but excessive neutrophil activity can lead to tissue damage and promote acute respiratory distress syndrome. COVID-19 is associated with systemic expansion of immature neutrophils, but the functiona
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::101394793974f4e503b9f284a6d03748
https://doi.org/10.26508/lsa.202201658
https://doi.org/10.26508/lsa.202201658
Autor:
Bombaci, Giuseppe, Sarangdhar, Mayuresh Anant, Andina, Nicola, Tardivel, Aubry, Yu, Eric Chi-Wang, Mackie, Gillian M, Pugh, Matthew, Ozan, Vedat Burak, Banz, Yara, Spinetti, Thibaud, Hirzel, Cedric, Youd, Esther, Schefold, Joerg C, Taylor, Graham, Gazdhar, Amiq, Bonadies, Nicolas, Angelillo-Scherrer, Anne, Schneider, Pascal, Maslowski, Kendle M, Allam, Ramanjaneyulu
Publikováno v:
Life science alliance, vol. 5, no. 6, pp. e202101226
Bombaci, Giuseppe; Sarangdhar, Mayuresh Anant; Andina, Nicola; Tardivel, Aubry; Yu, Eric Chi-Wang; Mackie, Gillian M; Pugh, Matthew; Ozan, Vedat Burak; Banz, Yara; Spinetti, Thibaud; Hirzel, Cédric; Youd, Esther; Schefold, Joerg C; Taylor, Graham; Gazdhar, Amiq; Bonadies, Nicolas; Angelillo-Scherrer, Anne; Schneider, Pascal; Maslowski, Kendle M and Allam, Ramanjaneyulu (2022). LRR-protein RNH1 dampens the inflammasome activation and is associated with COVID-19 severity. Life science alliance, 5(6) EMBO Press 10.26508/lsa.202101226
Bombaci, Giuseppe; Sarangdhar, Mayuresh Anant; Andina, Nicola; Tardivel, Aubry; Yu, Eric Chi-Wang; Mackie, Gillian M; Pugh, Matthew; Ozan, Vedat Burak; Banz, Yara; Spinetti, Thibaud; Hirzel, Cédric; Youd, Esther; Schefold, Joerg C; Taylor, Graham; Gazdhar, Amiq; Bonadies, Nicolas; Angelillo-Scherrer, Anne; Schneider, Pascal; Maslowski, Kendle M and Allam, Ramanjaneyulu (2022). LRR-protein RNH1 dampens the inflammasome activation and is associated with COVID-19 severity. Life science alliance, 5(6) EMBO Press 10.26508/lsa.202101226
Inflammasomes are cytosolic innate immune sensors of pathogen infection and cellular damage that induce caspase-1-mediated inflammation upon activation. Although inflammation is protective, uncontrolled excessive inflammation can cause inflammatory d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::488bbd9efd7f819f11109a566511bb94
https://pubmed.ncbi.nlm.nih.gov/35256513
https://pubmed.ncbi.nlm.nih.gov/35256513