Midregional Proatrial Natriuretic Peptide (MRproANP) is associated with vertebral fractures and low bone density in patients with chronic obstructive pulmonary disease (COPD)

Autor: Franziska C. Trudzinski, Rudolf A. Jörres, Peter Alter, Henrik Watz, Claus F. Vogelmeier, Hans-Ulrich Kauczor, Subasini Thangamani, Manuel Debic, Tobias Welte, Jürgen Behr, Kathrin Kahnert, Robert Bals, Christian Herr, Claus Peter Heußel, Jürgen Biederer, Oyunbileg von Stackelberg, Sebastian Fähndrich, Emiel F. M. Wouters, Benjamin Waschki, Klaus F. Rabe, Felix J. F. Herth, Viktoria Palm, COSYCONET study group

Publikováno v: Respiratory Research, Vol 25, Iss 1, Pp 1-11 (2024)

Abstract Background Patients with COPD are often affected by loss of bone mineral density (BMD) and osteoporotic fractures. Natriuretic peptides (NP) are known as cardiac markers, but have also been linked to fragility-associated fractures in the eld

Externí odkaz: https://doaj.org/article/adadd9ca5c334e58ae95cbe9771279f4

Sex-specific associations of comorbidome and pulmorbidome with mortality in chronic obstructive pulmonary disease: results from COSYCONET

Autor: Franziska C. Trudzinski, Rudolf A. Jörres, Peter Alter, Julia Walter, Henrik Watz, Andrea Koch, Matthias John, Marek Lommatzsch, Claus F. Vogelmeier, Hans-Ulrich Kauczor, Tobias Welte, Jürgen Behr, Amanda Tufman, Robert Bals, Felix J. F. Herth, Kathrin Kahnert, The COSYCONET Study Group

Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)

Abstract In patients with COPD, it has not been comprehensively assessed whether the predictive value of comorbidities for mortality differs between men and women. We therefore aimed to examine sex differences of COPD comorbidities in regard with pro

Externí odkaz: https://doaj.org/article/51c621bd8e324fefa23aea0da7193a99

Reduced decline of lung diffusing capacity in COPD patients with diabetes and metformin treatment

Autor: Kathrin Kahnert, Stefan Andreas, Christina Kellerer, Johanna I. Lutter, Tanja Lucke, Önder Yildirim, Mareike Lehmann, Jochen Seissler, Jürgen Behr, Marion Frankenberger, Robert Bals, Henrik Watz, Tobias Welte, Franziska C. Trudzinski, Claus F. Vogelmeier, Peter Alter, Rudolf A. Jörres, COSYCONET Study Group

Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)

Abstract We studied whether in patients with COPD the use of metformin for diabetes treatment was linked to a pattern of lung function decline consistent with the hypothesis of anti-aging effects of metformin. Patients of GOLD grades 1–4 of the COS

Externí odkaz: https://doaj.org/article/2d066f4a1cea4521a09eea5714232b57

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GOLD-Grade Specific Disease Characterization and Phenotyping of COPD Using Quantitative Computed Tomography in the Nationwide COSYCONET Multicenter Trial in Germany.

Autor: Konietzke P; Department of Diagnostic and Interventional Radiology, University Hospital of Heidelberg, Heidelberg, Germany.; Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), University of Heidelberg, Heidelberg, Germany.; Department of Diagnostic and Interventional Radiology with Nuclear Medicine, Thorax Clinic at University of Heidelberg, Heidelberg, Germany., Weinheimer O; Department of Diagnostic and Interventional Radiology, University Hospital of Heidelberg, Heidelberg, Germany.; Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), University of Heidelberg, Heidelberg, Germany.; Department of Diagnostic and Interventional Radiology with Nuclear Medicine, Thorax Clinic at University of Heidelberg, Heidelberg, Germany., Triphan SMF; Department of Diagnostic and Interventional Radiology, University Hospital of Heidelberg, Heidelberg, Germany.; Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), University of Heidelberg, Heidelberg, Germany.; Department of Diagnostic and Interventional Radiology with Nuclear Medicine, Thorax Clinic at University of Heidelberg, Heidelberg, Germany., Nauck S; Department of Diagnostic and Interventional Radiology, University Hospital of Heidelberg, Heidelberg, Germany.; Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), University of Heidelberg, Heidelberg, Germany.; Department of Diagnostic and Interventional Radiology with Nuclear Medicine, Thorax Clinic at University of Heidelberg, Heidelberg, Germany., Wuennemann F; Department of Diagnostic and Interventional Radiology, University Hospital of Heidelberg, Heidelberg, Germany.; Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), University of Heidelberg, Heidelberg, Germany.; Department of Diagnostic and Interventional Radiology with Nuclear Medicine, Thorax Clinic at University of Heidelberg, Heidelberg, Germany., Konietzke M; Department of Diagnostic and Interventional Radiology, University Hospital of Heidelberg, Heidelberg, Germany.; Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), University of Heidelberg, Heidelberg, Germany.; Department of Diagnostic and Interventional Radiology with Nuclear Medicine, Thorax Clinic at University of Heidelberg, Heidelberg, Germany., Jobst BJ; Department of Diagnostic and Interventional Radiology, University Hospital of Heidelberg, Heidelberg, Germany.; Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), University of Heidelberg, Heidelberg, Germany.; Department of Diagnostic and Interventional Radiology with Nuclear Medicine, Thorax Clinic at University of Heidelberg, Heidelberg, Germany., Jörres RA; Institute and Outpatient Clinic for Occupational, Social and Environmental Medicine, Ludwig Maximilians University, Munich, Germany.; Comprehensive Pneumology Center Munich (CPC-M), Munich, Germany., Vogelmeier CF; Department of Medicine, Pulmonary and Critical Care Medicine, German Center for Lung Research (DZL), University Medical Center Giessen and Marburg, Giessen, Germany., Heussel CP; Department of Diagnostic and Interventional Radiology, University Hospital of Heidelberg, Heidelberg, Germany.; Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), University of Heidelberg, Heidelberg, Germany.; Department of Diagnostic and Interventional Radiology with Nuclear Medicine, Thorax Clinic at University of Heidelberg, Heidelberg, Germany., Kauczor HU; Department of Diagnostic and Interventional Radiology, University Hospital of Heidelberg, Heidelberg, Germany.; Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), University of Heidelberg, Heidelberg, Germany.; Department of Diagnostic and Interventional Radiology with Nuclear Medicine, Thorax Clinic at University of Heidelberg, Heidelberg, Germany., Biederer J; Department of Diagnostic and Interventional Radiology, University Hospital of Heidelberg, Heidelberg, Germany.; Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), University of Heidelberg, Heidelberg, Germany.; Faculty of Medicine, University of Latvia, Riga, Latvia.; Faculty of Medicine, Christian-Albrechts-University of Kiel, Kiel, Germany., Wielpütz MO; Department of Diagnostic and Interventional Radiology, University Hospital of Heidelberg, Heidelberg, Germany.; Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), University of Heidelberg, Heidelberg, Germany.; Department of Diagnostic and Interventional Radiology with Nuclear Medicine, Thorax Clinic at University of Heidelberg, Heidelberg, Germany.

Publikováno v: Respiration; international review of thoracic diseases [Respiration] 2024 Aug 22, pp. 1-17. Date of Electronic Publication: 2024 Aug 22.