Výsledky vyhledávání - "COPANI AGATA"

Akademický článek

Hyperalgesic activity of kisspeptin in mice

Autor: Spampinato Simona, Trabucco Angela, Biasiotta Antonella, Biagioni Francesca, Cruccu Giorgio, Copani Agata, Colledge William H, Sortino Maria, Nicoletti Ferdinando, Chiechio Santina

Publikováno v: Molecular Pain, Vol 7, Iss 1, p 90 (2011)

Abstract Background Kisspeptin is a neuropeptide known for its role in the hypothalamic regulation of the reproductive axis. Following the recent description of kisspeptin and its 7-TM receptor, GPR54, in the dorsal root ganglia and dorsal horns of t

Externí odkaz: https://doaj.org/article/2f298c0f6cd0405d9160ba9820027105

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Akademický článek

mGlu2 metabotropic glutamate receptors restrain inflammatory pain and mediate the analgesic activity of dual mGlu2/mGlu3 receptor agonists

Autor: Copani Agata, Traficante Anna, Montana Michael C, Chiechio Santina, Zammataro Magda, Nicoletti Ferdinando, Gereau Robert W

Publikováno v: Molecular Pain, Vol 7, Iss 1, p 6 (2011)

Abstract Group II metabotropic glutamate receptors (mGluRs) couple to the inhibitory G-protein Gi. The group II mGluRs include two subtypes, mGlu2 and mGlu3, and their pharmacological activation produces analgesic effects in inflammatory and neuropat

Externí odkaz: https://doaj.org/article/79ca6a4259ff400aa762f0a2d50b290f

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Akademický článek

Transcriptional regulation of metabotropic glutamate receptor 2/3 expression by the NF-κB pathway in primary dorsal root ganglia neurons: a possible mechanism for the analgesic effect of L-acetylcarnitine

Autor: Nicoletti Ferdinando, Morales Maria Elena P, De Petris Laura, Copani Agata, Chiechio Santina, Gereau Robert W

Publikováno v: Molecular Pain, Vol 2, Iss 1, p 20 (2006)

Abstract L-acetylcarnitine (LAC), a drug utilized for the treatment of neuropathic pain in humans, has been shown to induce analgesia in rodents by up-regulating the expression of metabotropic glutamate receptor 2 (mGlu2) in dorsal root ganglia (DRG)

Externí odkaz: https://doaj.org/article/da8eab8d7c074443b2519a5e979d344b

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Akademický článek

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Molecular Connections between DNA Replication and Cell Death in β-Amyloid-Treated Neurons

Autor: Caraci, Filippo, Fidilio, Annamaria, Rosa, Santangelo, Giuseppe, Caruso, Giuffrida, MARIA LAURA, Marianna Flora Tomasello, Ferdinando, Nicoletti, Copani, Agata Graziella

Publikováno v: Current Neuropharmacology. 21:2006-2018

Background: Ectopic cell cycle reactivation in neurons is associated with neuronal death in Alzheimer’s disease. In cultured rodent neurons, synthetic β-amyloid (Aβ) reproduces the neuronal cell cycle re-entry observed in the Alzheimer’s brain,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fcf6beadb5df130936a3050b8244bf2
https://doi.org/10.2174/1570159x21666230404121903

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