Zobrazeno 1 - 8
of 8
pro vyhledávání: '"CONRAD REIHSMANN"'
Autor:
Yicheng Tao, Fan Feng, Xin Luo, Conrad Reihsmann, Alexander Hopkirk, Diane Saunders, Marcela Brissova, Stephen Parker, Jie Liu
Recent studies show that cellular neighborhoods play an important role in evolving biological events such as cancer and diabetes. Therefore, it is critical to accurately and efficiently identify cellular neighborhoods from spatially-resolved single-c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::abf08a0eeb43a1c1a08fdd7bae8a3446
https://doi.org/10.21203/rs.3.rs-2212129/v1
https://doi.org/10.21203/rs.3.rs-2212129/v1
Autor:
MARCELA BRISSOVA, HEATHER H. DURAI, SHAOJUN MEI, ANASTASIA COLDREN, COREY DAVIS, CONRAD REIHSMANN, ALEXANDER L. HOPKIRK, DANNIELLE GIBSON, RADHIKA ARAMANDLA, GREG POFFENBERGER, DIANE C. SAUNDERS, ALVIN C. POWERS, JOYCE C. NILAND, CARMELLA EVANS-MOLINA
Publikováno v:
Diabetes. 71
The Integrated Islet Distribution Program (IIDP) is currently the largest source of human islets for research in the U.S. The IIDP Human Islet Phenotyping Program (HIPP) provides standardized islet assessment and makes these data available to researc
Autor:
TIFFANY M. RICHARDSON, CHUNHUA DAI, RADHIKA ARAMANDLA, HEATHER H. DURAI, CONRAD REIHSMANN, COREY DAVIS, SHAOJUN MEI, DANNIELLE GIBSON, SHRISTI SHRESTHA, DIANE C. SAUNDERS, KATIE C. COATE, SIMON C. ROBSON, ALVIN C. POWERS, MARCELA BRISSOVA
Publikováno v:
Diabetes. 71
ATP release from β cell secretory vesicles during insulin exocytosis is postulated to modulate islet hormone secretion via purinergic signaling in an autocrine or paracrine manner. Ecto-enzymes, including a family of ectonucleotidases (NTPDase) , co
This protocol describes the imaging workflow currently in use by the Vanderbilt Diabetes Research Center Islet & Pancreas Analysis (IPA) Core and Powers/Brissova Research Group for CO-Detection by indEXing (CODEX®, now PhenoCycler™; Akoya Bioscien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::117f442959a8d002853c63dc9c8312f9
https://doi.org/10.17504/protocols.io.e6nvwke6zvmk/v1
https://doi.org/10.17504/protocols.io.e6nvwke6zvmk/v1
This protocol describes the staining and pre-imaging preparation currently in use by the Vanderbilt Diabetes Research Center Islet & Pancreas Analysis (IPA) Core and Powers/Brissova Research Group prior to performing multiplexed imaging of the human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16593d41309d9f1a35cb1489d82b64b0
https://doi.org/10.17504/protocols.io.n92ldzro9v5b/v1
https://doi.org/10.17504/protocols.io.n92ldzro9v5b/v1
This protocol describes the antibody conjugation and validation processes for the CODEX® (now PhenoCycler™) system by Akoya Biosciences. For the comprehensive multiplexed imaging workflow currently in use at the Vanderbilt Diabetes Research Center
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a74424e91133acd99fa58dd85c54ed4
https://doi.org/10.17504/protocols.io.kxygxzwmzv8j/v1
https://doi.org/10.17504/protocols.io.kxygxzwmzv8j/v1
Autor:
Robert A. Hegele, Rita Bottino, Nripesh Prasad, Greg Poffenberger, John T. Walker, Marcela Brissova, Shristi Shrestha, Alvin C. Powers, Jenny Aurielle B. Babon, May Sanyoura, Andrea H. Ramirez, Conrad Reihsmann, Louis H. Philipson, Rachana Haliyur, Sally C. Kent, Sambra D. Redick, David M. Harlan, Radhika Aramandla
Publikováno v:
Journal of the Endocrine Society
Clinical and pathologic heterogeneity in type 1 diabetes is increasingly being recognized. Findings in the islets and pancreas of a 22-year-old male with 8 years of type 1 diabetes were discordant with expected results and clinical history (islet aut
Autor:
John T. Walker, Radhika Aramandla, Alvin C. Powers, Marcela Brissova, Gregory Poffenberger, Matthew Ishahak, Ashutosh Agarwal, Rachana Haliyur, Adolfo Garcia-Ocaña, Conrad Reihsmann, Peng Wang, Joseph R. Luchsinger, Heather A. Nelson, Rita Bottino, Diane C. Saunders
SUMMARYG-protein-coupled-receptors (GPCRs) modulate insulin secretion from β cells and glucagon secretion from α cells. Here, we developed an integrated approach to study the function of primary human islet cells using genetically modified pseudois
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bbb728f63f59c7bd958e490a5ea3863