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pro vyhledávání: '"CONJUGATE EXPORT PUMP"'
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Akademický článek
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Akademický článek
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Autor:
Elisabeth G.E. de Vries, Willem Vaalburg, Folkert Kuipers, Charles M. A. Bijleveld, Rick Havinga, N. Harry Hendrikse, Winette T. A. van der Graaf, Coby Meijer
Publikováno v:
Hendrikse, N H, Kuipers, F, Meijer, C, Havinga, R, Bijleveld, C M A, Van Der Graaf, W T A, Vaalburg, W & De Vries, E G E 2004, ' In vivo imaging of hepatobiliary transport function mediated by multidrug resistance associated protein and P-glycoprotein ', Cancer Chemotherapy and Pharmacology, vol. 54, no. 2, pp. 131-138 . https://doi.org/10.1007/s00280-004-0793-2
Cancer Chemotherapy and Pharmacology, 54(2), 131-138. SPRINGER
Cancer Chemotherapy and Pharmacology, 54(2), 131-138. Springer Verlag
Cancer Chemotherapy and Pharmacology, 54(2), 131-138. SPRINGER
Cancer Chemotherapy and Pharmacology, 54(2), 131-138. Springer Verlag
Multidrug resistance associated proteins (MRPs) and P-glycoprotein (P-gp) are involved in hepatobiliary transport of various compounds. Our aim was (1) to define transporter specificity of the cholescintigraphic agents 99mTc-HIDA and 99mTc-MIBI, whic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7b04e202ad730df01a39a7e7e225a07
https://doi.org/10.1007/s00280-004-0793-2
https://doi.org/10.1007/s00280-004-0793-2
Publikováno v:
Molecular Pharmacology. 64(1):154-159
Phenobarbital (PB) treatment impairs the biliary excretion of some organic anions. One mechanism may involve direct competition for biliary excretion by PB and/or a PB metabolite. Alternatively, PB may alter the expression and/or function of hepatic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dris___00893::26609fce4e865aad022501d22f88ecfa
https://hdl.handle.net/11370/af888198-7e9b-4501-86e3-31cd32884c4b
https://hdl.handle.net/11370/af888198-7e9b-4501-86e3-31cd32884c4b
Publikováno v:
European Journal of Pharmaceutical Sciences. 12(1):13-30
Hepatobiliary transport of endogenous and exogenous compounds is mediated by the coordinated action of multiple transport systems present at the sinusoidal (basolateral) and canalicular (apical) membrane domains of hepatocytes. During the last few ye
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dris___01423::9a1e26ebf64986739e4dfb8abdcee104
https://research.rug.nl/en/publications/8ad4d161-cdfe-49d0-a229-658eb597406e
https://research.rug.nl/en/publications/8ad4d161-cdfe-49d0-a229-658eb597406e
Publikováno v:
Current Pharmaceutical Design. 6(16):1653-1668
Chemotherapeutic treatment of cancer patients is often unsuccessful, due to the involvement of various mechanisms, leading to multidrug resistance (MDR). In this review, I describe the mechanisms involved in MDR. Furthermore, results obtained by imag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dris___01423::e7a59bdf650d4d461a4c584e55255371
https://research.rug.nl/en/publications/e5acd49a-6d4e-459f-9647-7846956bbccb
https://research.rug.nl/en/publications/e5acd49a-6d4e-459f-9647-7846956bbccb
Publikováno v:
Gut. 47(1):1-5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dris___01423::eae5e7761a3784a5bff0d52f6561b412
https://research.rug.nl/en/publications/2883782e-de81-4d4a-aeea-3d48a4ce9c76
https://research.rug.nl/en/publications/2883782e-de81-4d4a-aeea-3d48a4ce9c76
Publikováno v:
Seminars in liver disease. 20(3):323-337
Transport processes for larger organic solutes at the canalicular membrane are mainly driven by members of the superfamily of ATP-binding cassette (ABC) transporters. The funct ions of these transporters range from bile component secretion to xenobio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dris___01423::7e2ecd6df979c32e1adbe9e3b2e630a5
https://doi.org/10.1055/s-2000-9387
https://doi.org/10.1055/s-2000-9387
Autor:
Michael Müller, Plm Jansen
Publikováno v:
Gut, 47(1), 1-5. BMJ Publishing Group
Gut, 47(1), 1-5. BMJ PUBLISHING GROUP
Gut, 47(1), 1-5. BMJ PUBLISHING GROUP
There is a growing list of genetic diseases caused by defects of one of the members of the ATP binding cassette (ABC) transporter superfamily.1 ABC transporters mediate the energy dependent transport of peptides, steroid hormones, and drugs and their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93de79948a6193f16829329bae63e564
https://doi.org/10.1136/gut.47.1.1
https://doi.org/10.1136/gut.47.1.1