Zobrazeno 1 - 2
of 2
pro vyhledávání: '"COL1A1, collagen type I alpha 1 chain"'
Autor:
Philipp W. N. Schmid, Matthias Mörgelin, Jan M. Gebauer, Sinan Oecal, Ulrich Baumann, Johannes Buchner, Elena Theres Abraham
Publikováno v:
The Journal of Biological Chemistry
'Journal of Biological Chemistry ', vol: 297, pages: 101169-1-101169-13 (2021)
'Journal of Biological Chemistry ', vol: 297, pages: 101169-1-101169-13 (2021)
Collagens play important roles in development and homeostasis in most higher organisms. In order to function, collagens require the specific chaperone HSP47 for proper folding and secretion. HSP47 is known to bind to the collagen triple-helix but the
Autor:
Luca Miele, Erika Paolini, Miriam Longo, Valentina D'Oria, Annalisa Crudele, Marco Maggioni, Luca Valenti, Marica Meroni, Paola Dongiovanni, Emanuele Bellacchio, Anna Alisi, Nadia Panera, Anna Ludovica Fracanzani
Publikováno v:
EBioMedicine
EBioMedicine, Vol 65, Iss, Pp 103249-(2021)
EBioMedicine, Vol 65, Iss, Pp 103249-(2021)
Background The rs17618244 G>A β-Klotho (KLB) variant has been associated with increased risk of ballooning and inflammation in pediatric patients with metabolic associated fatty liver disease (MAFLD), by reducing KLB expression. In hepatocytes, KLB