Zobrazeno 1 - 10
of 209
pro vyhledávání: '"COL10A1"'
Publikováno v:
Renal Failure, Vol 46, Iss 1 (2024)
Acute kidney injury (AKI) can progress to renal fibrosis and chronic kidney disease (CKD), which reduces quality of life and increases the economic burden on patients. However, the molecular mechanisms underlying renal fibrosis following AKI remain u
Externí odkaz:
https://doaj.org/article/198aa8fe6e084ed18b5aca0d7aab66e7
Publikováno v:
BMC Gastroenterology, Vol 23, Iss 1, Pp 1-10 (2023)
Abstract Background Pancreatic adenocarcinoma (PAAD) is a lethal malignant tumour. Further study is needed to determine the molecular mechanism and identify novel biomarkers of PAAD. Methods Gene expression data from the GSE62165 microarray were anal
Externí odkaz:
https://doaj.org/article/4b0819a363854d8f9352c610ad58c3d0
Autor:
Jinnan Chen, Fangzhou Chen, Xuan Wu, Huiqin Bian, Chen Chen, Xiaojing Zhang, Ruoxuan Hei, XiaotongYang, Haochun Yuan, Qian Wang, Yaojuan Lu, Longwei Qiao, Qiping Zheng
Publikováno v:
Genes and Diseases, Vol 10, Iss 5, Pp 2097-2108 (2023)
Osteoarthritis (OA) has been considered non-reversible as articular cartilage wears down with limited repair capacity. Enhanced chondrocyte hypertrophy and increased type X collagen gene (COL10A1) expression have been associated with OA. Therefore, r
Externí odkaz:
https://doaj.org/article/a75b8d677be14a1bb95f982c9c99a0ce
Publikováno v:
陆军军医大学学报, Vol 45, Iss 8, Pp 842-846 (2023)
Objective Schmid type metaphyseal chondrodysplasia (SMCD) is an autosomal dominant chondrodysplasia characterized by abnormal gait and skeletal deformity of limbs. In the study, we analyzed the phenotype and genotype of SMCD in a family who were admi
Externí odkaz:
https://doaj.org/article/4113549d879149f7846574ff18c53a6b
Akademický článek
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Autor:
Xiaoming Wang, Yunjin Bai, Facai Zhang, Dengxiong Li, Kai Chen, Ruicheng Wu, Yin Tang, Xin Wei, Ping Han
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionBladder cancer (BLCA) is one of the most lethal diseases. COL10A1 is secreted small-chain collagen in the extracellular matrix associated with various tumors, including gastric, colon, breast, and lung cancer. However, the role of COL10A1
Externí odkaz:
https://doaj.org/article/0b2ce84ded2143c5bdfa346a8a1790b4
Autor:
Zhihui Wen, Jingbo Sun, Junjie Luo, Yun Fu, Yue Qiu, Yanyan Li, Yangwei Xu, Hongmei Wu, Qingling Zhang
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal malignant tumors with a poor prognosis. Type X collagen α 1 chain (COL10A1), a member of the collagen family, is a gene associated with the progression of a variety of human tumors, b
Externí odkaz:
https://doaj.org/article/f1df335d22314f919f0c01f346df2098
Akademický článek
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Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 9, Iss 10, Pp n/a-n/a (2021)
Abstract Background The collagen alpha‐1(X) chain gene (COL10A1) is a known causative gene for Schmid metaphyseal chondrodysplasia (SMCD). This study clinically examined a Chinese family (n = 42) for SMCD and inheritance pattern. Fifteen individual
Externí odkaz:
https://doaj.org/article/f3382b9a793d4a758843d73a1c83f42b
Autor:
Huiqin Bian, Ting Zhu, Yuting Liang, Ruoxuan Hei, Xiaojing Zhang, Xiaochen Li, Jinnan Chen, Yaojuan Lu, Junxia Gu, Longwei Qiao, Qiping Zheng
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Hypertrophic chondrocytes and their specific marker, the type X collagen gene (Col10a1), are critical components of endochondral bone formation during skeletal development. We previously found that Runx2 is an indispensable mouse Col10a1 gene regulat
Externí odkaz:
https://doaj.org/article/b1b34507dc274e6b9ba0a52d5f27e508