Výsledky vyhledávání - "COENEGRACHT, PMJ"

Multivariate quality assessment of aged RP-HPLC columns

Autor: Bolck, A, Smilde, AK, Duineveld, KAA, Coenegracht, PMJ

Publikováno v: Journal of Chemometrics, 10(5-6), 351-370

The inner structure of RP-HPLC columns can change ('age') during routine use. The columns may be monitored to check the magnitude and type of the changes. One approach is to investigate, besides the chromatograms, the retention behaviour of a few sel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::5222df1894f50eada600e6df35c2c613
https://research.rug.nl/en/publications/34cd57b0-9719-4a78-85e2-1e6fce1fff0f

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ARTIFICIAL NEURAL-NETWORK PREDICTIONS OF URINARY CALCULUS COMPOSITIONS ANALYZED WITH INFRARED-SPECTROSCOPY

Autor: VOLMER, M, WOLTHERS, BG, METTING, HJ, DEHAAN, THY, COENEGRACHT, PMJ, VANDERSLIK, W

Publikováno v: Clinical Chemistry, 40(9), 1692-1697. AMER ASSOC CLINICAL CHEMISTRY

Infrared (IR) spectroscopy is used to analyze urinary calculus (renal stone) constituents. However, interpretation of IR spectra for quantifying urinary calculus constituents in mixtures is difficult, requiring expert knowledge by trained technicians

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::3cd4abf1ce378a8a5314bc5b3ed0a3ec
https://research.rug.nl/en/publications/05b4014b-09a7-47d1-b0c1-41a0191ee499

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ROBUSTNESS TESTING OF AN OPTIMIZED REVERSED-PHASE HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC SYSTEM FOR THE SEPARATION OF 6 SULFONAMIDES USING THE RULES OF ERROR PROPAGATION

Autor: WIELING, J, COENEGRACHT, PMJ, DOORNBOS, DA, JONKMAN, JHG

Publikováno v: Journal of Chromatography A, 635(2), 195-202. ELSEVIER SCIENCE BV

In a previous investigation, the composition of the mobile phase for the reversed-phase HPLC separation of twelve sulphonamides was optimized. The predicted chromatogram showed great similarity with a chromatogram measured under optimum conditions. F

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::2dbf4a2564c8319d65c1eda2731e2f97
https://research.rug.nl/en/publications/95c127c0-3c9f-4e05-8011-0ff6aa0ae172

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CHEMOMETRICS IN BIOANALYTICAL SAMPLE PREPARATION - A FRACTIONATED COMBINED MIXTURE AND FACTORIAL DESIGN FOR THE MODELING OF THE RECOVERY OF 5 TRICYCLIC AMINES FROM PLASMA AFTER LIQUID-LIQUID-EXTRACTION PRIOR TO HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY

Autor: WIELING, J, MENSINK, CK, JONKMAN, JHG, COENEGRACHT, PMJ, DUINEVELD, CAA, DOORNBOS, DA

Publikováno v: Journal of Chromatography A, 629(2), 181-199. ELSEVIER SCIENCE BV

A general systematic approach is described for the chemometric modelling of liquid-liquid extraction data of drugs from biological fluids. Extraction solvents were selected from Snyder's solvent selectivity triangle: methyl tert.-butyl ether, methyle

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::75230c903d984b4c85faa7385b5ed140
https://research.rug.nl/en/publications/907fc4bf-b238-49ac-bf61-0ba8422107ac

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SELECTION OF ROBUST COMBINATIONS OF EXTRACTION LIQUID COMPOSITION AND INTERNAL STANDARD - MONTE-CARLO SIMULATION OF IMPROVEMENT OF ASSAY-METHODS WITH LIQUID-LIQUID-EXTRACTION PRIOR TO HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY

Autor: WIELING, J, COENEGRACHT, PMJ, MENSINK, CK, JONKMAN, JHG, DOORNBOS, DA

Publikováno v: Journal of Chromatography A, 594(1-2), 45-64. ELSEVIER SCIENCE BV

The liquid-liquid extraction of a mixture of sulphonamides was achieved to examine the correlation between the experimental errors in the recoveries. Also, the impact of the composition of the extraction liquid was investigated. Six sulphonamides wer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::893097d7496a51314e930370c907bcef
https://research.rug.nl/en/publications/cf736b7f-83cf-4784-9dd5-a3717b96cc34

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A NEW QUATERNARY MOBILE PHASE SYSTEM FOR OPTIMIZATION OF TLC SEPARATIONS OF ALKALOIDS USING MIXTURE DESIGNS AND RESPONSE-SURFACE MODELING

Autor: COENEGRACHT, PMJ, DIJKMAN, M, DUINEVELD, CAA, METTING, HJ, ELEMA, ET, MALINGRE, TM

Publikováno v: Journal of Liquid Chromatography, 14(16-17), 3213-3239

A new combination of four organic solvents is proposed for the optimization of TLC separations of basic drugs and alkaloids. The solvents are diethylamine (DEA), methanol (MeOH), chloroform (CHCl3) and ethylacetate (EtAc). They were selected from a c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::1d0dc91f981c3d22584727b600b545dc
https://research.rug.nl/en/publications/a3cc789c-218b-4948-9d2c-64789b950b96

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DEVELOPMENT OF A LABORATORY ROBOTIC SYSTEM FOR AUTOMATED BIOANALYTICAL METHODS .2. A ROBOT COMPUTER-PROGRAM FOR GUARDING TOTALLY AUTOMATED BIOANALYTICAL METHODS

Autor: WIELING, J, HEMPENIUS, J, JEURING, HJ, JONKMAN, JHG, COENEGRACHT, PMJ, DOORNBOS, DA

Publikováno v: Journal of Pharmaceutical and Biomedical Analysis, 8(7), 577-582. ELSEVIER SCIENCE BV

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::e781c37ca94b5c9efbf1f01fb975d64b
https://research.rug.nl/en/publications/f937f081-564e-4f08-85f8-4b6312ae4370

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DEVELOPMENT OF A LABORATORY ROBOTIC SYSTEM FOR AUTOMATED BIOANALYTICAL METHODS .1. THE DETERMINATION OF THEOPHYLLINE IN HUMAN PLASMA - A COMPARISON BETWEEN THE ROBOTIZED AND MANUAL METHOD

Autor: HEMPENIUS, J, WIELING, J, JONKMAN, JHG, DENOORD, OE, COENEGRACHT, PMJ, DOORNBOS, DA

Publikováno v: Journal of Pharmaceutical and Biomedical Analysis, 8(4), 313-320. ELSEVIER SCIENCE BV

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::7b887dbb11cbda8aafa3170846b624a3
https://research.rug.nl/en/publications/f5150a2f-9c9c-4e15-9306-bded51bf7f91

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