Zobrazeno 1 - 10
of 767
pro vyhledávání: '"CNTNAP2"'
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-20 (2024)
Abstract Microglial abnormality and heterogeneity are observed in autism spectrum disorder (ASD) patients and animal models of ASD. Microglial depletion by colony stimulating factor 1-receptor (CSF1R) inhibition has been proved to improve autism-like
Externí odkaz:
https://doaj.org/article/77b7a0f9f4b2458a913ab3f6913bb31c
Autor:
Paolina Crocco, Francesco De Rango, Francesco Bruno, Antonio Malvaso, Raffaele Maletta, Amalia C. Bruni, Giuseppe Passarino, Giuseppina Rose, Serena Dato
Publikováno v:
Heliyon, Vol 10, Iss 11, Pp e31624- (2024)
The Forkhead box P2 (FOXP2) is an evolutionary conserved transcription factor involved in the maintenance of neuronal networks, implicated in language disorders. Some evidence suggests a possible link between FOXP2 genetic variability and frontotempo
Externí odkaz:
https://doaj.org/article/e972a711805442169ef3c2c55539b42d
Autor:
Norman Panza, Claudia Bianchini, Valentina Cetica, Simona Balestrini, Carmen Barba, Anna Rita Ferrari, Davide Mei, Lucio Parmeggiani, Elena Parrini, Renzo Guerrini
Publikováno v:
Epilepsia Open, Vol 9, Iss 1, Pp 417-423 (2024)
Abstract Biallelic CNTNAP2 variants have been associated with Pitt‐Hopkins‐like syndrome. We describe six novel and one previously reported patients from six independent families and review the literature including 64 patients carrying biallelic
Externí odkaz:
https://doaj.org/article/7902d28e2bec4967aa4ee69bd3219bff
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Mojgan Rastegar
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 17 (2024)
Externí odkaz:
https://doaj.org/article/ed0d7cef255d4b3d93135cab1c0e5bcf
Publikováno v:
Journal of Integrative Neuroscience, Vol 23, Iss 3, p 63 (2024)
Background: Rats with a loss-of-function mutation in the contactin-associated protein-like 2 (Cntnap2) gene have been validated as an animal model of autism spectrum disorder (ASD). Similar to many autistic individuals, Cntnap2 knock-out rats (Cntnap
Externí odkaz:
https://doaj.org/article/0e9ede3f3b734b5c9179b0f4994e3745
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
Gastrointestinal (GI) symptoms are highly prevalent among individuals with autism spectrum disorder (ASD), but the molecular link between ASD and GI dysfunction remains poorly understood. The enteric nervous system (ENS) is critical for normal GI mot
Externí odkaz:
https://doaj.org/article/2c6f9baaadec443fb45f22ee7c58dbf2
Autor:
Yuka Shiota, Tetsu Hirosawa, Yuko Yoshimura, Sanae Tanaka, Chiaki Hasegawa, Sumie Iwasaki, Masuhiko Sano, Kyung‐min An, Shigeru Yokoyama, Mitsuru Kikuchi
Publikováno v:
Neuropsychopharmacology Reports, Vol 42, Iss 3, Pp 352-355 (2022)
Abstract Aim The receptive language ability of individuals with autism spectrum disorder (ASD) seems to lag behind expressive language ability. Several autism‐related genes may influence this developmental delay. Polymorphism of one such gene, name
Externí odkaz:
https://doaj.org/article/131075c2104543628a5d0309a90578a4
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
IntroductionHypoxia is an environmental risk factor for many disorders throughout life. Perinatal hypoxia contributes to autism spectrum disorder (ASD), while hypoxic conditions in the elderly facilitate memory deficits. However, the effects of hypox
Externí odkaz:
https://doaj.org/article/ba49dc8e2b31407ca60def5732705574