Zobrazeno 1 - 10
of 1 475
pro vyhledávání: '"CNS injury"'
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Oligodendrocyte precursor cells (OPCs) have long been regarded as progenitors of oligodendrocytes, yet recent advances have illuminated their multifaceted nature including their emerging immune functions. This review seeks to shed light on the immune
Externí odkaz:
https://doaj.org/article/dceff4fe4aaa49c9b4d0427e392b2a79
Autor:
Olivia J. Kalimon, Hemendra J. Vekaria, Gopal V. Velmurugan, W. Brad Hubbard, Patrick G. Sullivan
Publikováno v:
Neurotrauma Reports, Vol 4, Iss 1, Pp 627-642 (2023)
Traumatic brain injury (TBI) is caused by an impact or penetrating injury to the head resulting in abnormal brain function. Mitochondrial dysfunction is an important hallmark of TBI and has been thoroughly studied in male rodent models of brain injur
Externí odkaz:
https://doaj.org/article/546dfda817774a33880b1afc465a2a50
Autor:
Brittney R. Lins, Chidozie C. Anyaegbu, Sarah C. Hellewell, Melissa Papini, Terence McGonigle, Luca De Prato, Matthew Shales, Melinda Fitzgerald
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-21 (2023)
Abstract Traumatic brain injury is common, and often results in debilitating consequences. Even mild traumatic brain injury leaves approximately 20% of patients with symptoms that persist for months. Despite great clinical need there are currently no
Externí odkaz:
https://doaj.org/article/644dd3a87c694826842c19ca5d8a5e5e
Akademický článek
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Autor:
David P. Stonko, Michael J. Richmond, Joseph Edwards, Hossam Abdou, Rebecca Treffalls, Noha Elansary, Neerav Patel, Neeraj Badjatia, Kyle Jewhurst, Michaelina Dupnik, Kristian DiMatteo, Ryan Myers, Jonathan J Morrison
Publikováno v:
Surgery in Practice and Science, Vol 12, Iss , Pp 100154- (2023)
Introduction: Targeted temperature management plays an important role in the treatment of myriad critical illnesses. Non-invasive, quick-onset options for isolated brain temperature control remain lacking. The goal of this study was to assess the saf
Externí odkaz:
https://doaj.org/article/44b3e24e743a4e288b523c39f4d91504
Publikováno v:
Inflammation and Regeneration, Vol 42, Iss 1, Pp 1-10 (2022)
Abstract Neuropathic pain is often chronic and can persist after overt tissue damage heals, suggesting that its underlying mechanism involves the alteration of neuronal function. Such an alteration can be a direct consequence of nerve damage or a res
Externí odkaz:
https://doaj.org/article/c49e89bf5ed54afa8d3264962f2e18e5
Publikováno v:
Neural Regeneration Research, Vol 17, Iss 10, Pp 2157-2165 (2022)
Injuries to the central nervous system (CNS) such as stroke, brain, and spinal cord trauma often result in permanent disabilities because adult CNS neurons only exhibit limited axon regeneration. The brain has a surprising intrinsic capability of rec
Externí odkaz:
https://doaj.org/article/37560992380146a9a0c83f42eedeb169
Autor:
María Portela-Lomba, Diana Simón, David Fernández de Sevilla, Mª Teresa Moreno-Flores, Javier Sierra
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
An approach to generate new neurons after central nervous system injury or disease is direct reprogramming of the individual's own somatic cells into differentiated neurons. This can be achieved either by transduction of viral vectors that express ne
Externí odkaz:
https://doaj.org/article/8add2b1e57b647c6b4dd150d5303f65a
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 18, Iss 5 (2022)
Background After trauma and central nervous system (CNS) injury, trauma-induced immune deficiency syndrome (TIDS) and CNS injury-induced immune deficiency syndrome (CIDS) may negatively affect responses to T-cell-dependent vaccines, such as pneumococ
Externí odkaz:
https://doaj.org/article/2c6162623ef8406da4f7118e60eb24c0
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The central nervous system is the most important nervous system in vertebrates, which is responsible for transmitting information to the peripheral nervous system and controlling the body’s activities. It mainly consists of the brain and spinal cor
Externí odkaz:
https://doaj.org/article/bc5e70e8311742a88f38f3e3ced939f2