Activation of Nrf2/HO-1 signaling: An important molecular mechanism of herbal medicine in the treatment of atherosclerosis

Autor: Qing, Zhang, Jia, Liu, Huxinyue, Duan, Ruolan, Li, Wei, Peng, Chunjie, Wu

Publikováno v: Journal of Advanced Research

Graphical abstract
Introduction Recently, Nrf2/HO-1 has received extensive attention as the main regulatory pathway of intracellular defense against oxidative stress and is considered an ideal target for alleviating endothelial cell (EC) injury.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9de6be7acea23fd93887832ef07452a1
https://pubmed.ncbi.nlm.nih.gov/35024180

Arginine methylation of SKN-1 promotes oxidative stress resistance in Caenorhabditis elegans

Autor: Baiqu Huang, Dan Wang, Hongyuan Li, Yu Zhang, Xin Liu, Hongmei Li, Jun Lu, Liangping Su, Xin Su, Xiaoxue Li, Xueqing Ba

Publikováno v: Redox Biology, Vol 21, Iss, Pp-(2019)
Redox Biology

Caenorhabditis elegans NRF (NF-E2-related factor)/CNC (Cap'n'collar) transcription factor, Skinhead-1 (SKN-1), is conservatively critical for promoting phase II detoxification gene expressions in response to oxidative stress. SKN-1 activity is contro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b090703b70a8ef0725d226851957646
https://doi.org/10.1016/j.redox.2019.101111

Ferroptosis model system by the re-expression of BACH1.

Autor: Irikura R; Department of Biochemistry, Tohoku University Graduate School of Medicine, 2-1 Seiryo-machi, Aoba-ku, Sendai 980-8575, Japan., Nishizawa H; Department of Biochemistry, Tohoku University Graduate School of Medicine, 2-1 Seiryo-machi, Aoba-ku, Sendai 980-8575, Japan., Nakajima K; Department of Biochemistry, Tohoku University Graduate School of Medicine, 2-1 Seiryo-machi, Aoba-ku, Sendai 980-8575, Japan., Yamanaka M; Department of Biochemistry, Tohoku University Graduate School of Medicine, 2-1 Seiryo-machi, Aoba-ku, Sendai 980-8575, Japan.; Gladstone Institute of Neurological Disease, Gladstone Institutes, 1650 Owens Street, San Francisco, CA 94158, USA., Chen G; Department of Molecular Oncology, Institute of Development, Aging and Cancer (IDAC), Tohoku University, 4-1 Seiryo-machi, Aoba-ku, Sendai 980-8575, Japan., Tanaka K; Department of Molecular Oncology, Institute of Development, Aging and Cancer (IDAC), Tohoku University, 4-1 Seiryo-machi, Aoba-ku, Sendai 980-8575, Japan., Onodera M; Gene & Cell Therapy Promotion Center, National Center for Child Health and Development, 2-10-1 Okura, Setagaya-ku, Tokyo 157-8535, Japan., Matsumoto M; Department of Biochemistry, Tohoku University Graduate School of Medicine, 2-1 Seiryo-machi, Aoba-ku, Sendai 980-8575, Japan.; Center for Regulatory Epigenome and Diseases, Tohoku University Graduate School of Medicine, 2-1 Seiryo-machi, Aoba-ku, Sendai 980-8575, Japan., Igarashi K; Department of Biochemistry, Tohoku University Graduate School of Medicine, 2-1 Seiryo-machi, Aoba-ku, Sendai 980-8575, Japan.; Center for Regulatory Epigenome and Diseases, Tohoku University Graduate School of Medicine, 2-1 Seiryo-machi, Aoba-ku, Sendai 980-8575, Japan.

Publikováno v: Journal of biochemistry [J Biochem] 2023 Jul 31; Vol. 174 (3), pp. 239-252.

Whole-exome mutational landscape of metastasis in patient-derived hepatocellular carcinoma cells.

Autor: Zhou Q; Key Laboratory of Molecular Biology on Infectious Diseases, Ministry of Education, Chongqing, China.; Institute for Viral Hepatitis, Chongqing Medical University, Chongqing, China.; Department of Infectious Diseases, Second Affiliated Hospital, Chongqing Medical University, Chongqing, China., Li Z; Key Laboratory of Molecular Biology on Infectious Diseases, Ministry of Education, Chongqing, China.; Institute for Viral Hepatitis, Chongqing Medical University, Chongqing, China.; Department of Infectious Diseases, Second Affiliated Hospital, Chongqing Medical University, Chongqing, China., Song L; Key Laboratory of Molecular Biology on Infectious Diseases, Ministry of Education, Chongqing, China.; Institute for Viral Hepatitis, Chongqing Medical University, Chongqing, China.; Department of Infectious Diseases, Second Affiliated Hospital, Chongqing Medical University, Chongqing, China., Mu D; Key Laboratory of Molecular Biology on Infectious Diseases, Ministry of Education, Chongqing, China.; Institute for Viral Hepatitis, Chongqing Medical University, Chongqing, China.; Department of Infectious Diseases, Second Affiliated Hospital, Chongqing Medical University, Chongqing, China., Wang J; Key Laboratory of Molecular Biology on Infectious Diseases, Ministry of Education, Chongqing, China.; Institute for Viral Hepatitis, Chongqing Medical University, Chongqing, China.; Department of Infectious Diseases, Second Affiliated Hospital, Chongqing Medical University, Chongqing, China., Tian L; Key Laboratory of Molecular Biology on Infectious Diseases, Ministry of Education, Chongqing, China.; Institute for Viral Hepatitis, Chongqing Medical University, Chongqing, China.; Department of Infectious Diseases, Second Affiliated Hospital, Chongqing Medical University, Chongqing, China., Liao Y; Key Laboratory of Molecular Biology on Infectious Diseases, Ministry of Education, Chongqing, China.; Institute for Viral Hepatitis, Chongqing Medical University, Chongqing, China.; Department of Infectious Diseases, Second Affiliated Hospital, Chongqing Medical University, Chongqing, China.

Publikováno v: Genes & diseases [Genes Dis] 2020 May 15; Vol. 7 (3), pp. 380-391. Date of Electronic Publication: 2020 May 15 (Print Publication: 2020).