Zobrazeno 1 - 3
of 3
pro vyhledávání: '"CMS, consensus molecular subtype"'
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 10, Iss 2, Pp 391-418 (2020)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims The miR-34a gene is a direct target of p53 and is commonly silenced in colorectal cancer (CRC). Here we identified the receptor tyrosine kinase CSF1R as a direct miR-34a target and characterized CSF1R as an effector of p53/miR-34a-m
Autor:
David J. Papke, Tomotaka Ugai, Shanshan Shi, Jeffrey A. Meyerhardt, Melissa Zhao, Annacarolina da Silva, Hongmei Nan, Jonathan A. Nowak, Marios Giannakis, Shuji Ogino, Naohiko Akimoto, Tyler S. Twombly, Andrew T. Chan, Xuehong Zhang, Mai Chan Lau, Mingyang Song, Koichiro Haruki, Simeng Gu, Juha P. Väyrynen, Kenji Fujiyoshi, Kota Arima, Jennifer Borowsky, Kana Wu, Jochen K. Lennerz, Junko Kishikawa, Charles S. Fuchs
Publikováno v:
EBioMedicine
EBioMedicine, Vol 57, Iss, Pp 102860-(2020)
EBioMedicine, Vol 57, Iss, Pp 102860-(2020)
Background/Objectives: Tumour budding and poorly differentiated clusters (PDC) represent forms of tumour invasion. We hypothesised that T-cell densities (reflecting adaptive anti-tumour immunity) might be inversely associated with tumour budding and
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 7, Iss 4, Pp 783-802 (2019)
Cellular and Molecular Gastroenterology and Hepatology, Vol 7, Iss 4, Pp 783-802 (2019)
Background & Aims Intratumor heterogeneity is a common feature of colorectal cancer (CRC). Here, we analyzed whether mesenchymal-like CRC cells promote the progression of epithelial-like CRC cells via paracrine mechanisms. Methods Six CRC cell lines