Zobrazeno 1 - 2
of 2
pro vyhledávání: '"CM Sheckler"'
Autor:
Peter J. Prince, Wei-Jian Pan, Larry C. Wienkers, XZ Xia, CM Sheckler, Hailing Hsu, C D Krill, Dominique C. Borie, AA Anderson, Ian Foltz, Palaniswami Rathanaswami, SP Lear, William A. Rees, Sonal K. Patel, F Lee, Kathy Manchulenko, BJ Harder, Doherty, JL Brandvig, JL Lynch, Brian Mingtung Chan, M Zhang, John A. Wisler, Kaz O Reynhardt
Publikováno v:
British Journal of Pharmacology. 169:51-68
Background and Purpose AMG 181 is a human anti-α4β7 antibody currently in phase 1 and 2 trials in subjects with inflammatory bowel diseases. AMG 181 specifically targets the α4β7 integrin heterodimer, blocking its interaction with mucosal address
Autor:
Pan WJ; Department of Pharmacokinetics and Drug Metabolism, Amgen Inc., Seattle, WA 98119-3105, USA. wpan@amgen.com, Hsu H, Rees WA, Lear SP, Lee F, Foltz IN, Rathanaswami P, Manchulenko K, Chan BM, Zhang M, Xia XZ, Patel SK, Prince PJ, Doherty DR, Sheckler CM, Reynhardt KO, Krill CD, Harder BJ, Wisler JA, Brandvig JL, Lynch JL, Anderson AA, Wienkers LC, Borie DC
Publikováno v:
British journal of pharmacology [Br J Pharmacol] 2013 May; Vol. 169 (1), pp. 51-68.