Abstract P1-16-03: Phase II randomized clinical trial (RCT) of metformin (MET) vs placebo (PLAC) in combination with chemotherapy (CXT) in refractory locally advanced (LABC) or metastatic breast cancer (MBC)

Autor: CM Hamm, Ana Elisa Lohmann, Marguerite Ennis, Rashida Haq, Martin C. Chang, Vuk Stambolic, David W. Cescon, Isabel Pimentel, Christine Elser, PJ Goodwin, Rjo Dowling

Publikováno v: Cancer Research. 79:P1-16

Background: MET treatment of diabetes is associated with improved BC outcomes. Hirsch et al (Cancer Res 2009;69:7505-7511) suggested MET may act synergistically with CXT in BC rodent models. We conducted a double-blind Phase II RCT of CXT plus MET vs

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3eeec087554ceba419005c6138e9212f
https://doi.org/10.1158/1538-7445.sabcs18-p1-16-03

Role of B1 and B2 lymphocytes in placental ischemia-induced hypertension.

Autor: Laule CF; Department of Biomedical Sciences, University of Minnesota Medical School, Duluth Campus, Duluth, Minnesota., Odean EJ; Department of Biomedical Sciences, University of Minnesota Medical School, Duluth Campus, Duluth, Minnesota., Wing CR; Department of Biomedical Sciences, University of Minnesota Medical School, Duluth Campus, Duluth, Minnesota., Root KM; Department of Biomedical Sciences, University of Minnesota Medical School, Duluth Campus, Duluth, Minnesota., Towner KJ; Department of Biomedical Sciences, University of Minnesota Medical School, Duluth Campus, Duluth, Minnesota., Hamm CM; Department of Biomedical Sciences, University of Minnesota Medical School, Duluth Campus, Duluth, Minnesota., Gilbert JS; Department of Biomedical Sciences, University of Minnesota Medical School, Duluth Campus, Duluth, Minnesota., Fleming SD; Division of Biology, Kansas State University, Manhattan, Kansas., Regal JF; Department of Biomedical Sciences, University of Minnesota Medical School, Duluth Campus, Duluth, Minnesota.

Publikováno v: American journal of physiology. Heart and circulatory physiology [Am J Physiol Heart Circ Physiol] 2019 Oct 01; Vol. 317 (4), pp. H732-H742. Date of Electronic Publication: 2019 Aug 09.

Disease phenotype and genotype are associated with shifts in intestinal-associated microbiota in inflammatory bowel diseases.

Autor: Frank DN; Department of Molecular, Cellular and Developmental Biology, University of Colorado, Boulder, Colorado 80045, USA. Daniel.Frank@Colorado.edu, Robertson CE, Hamm CM, Kpadeh Z, Zhang T, Chen H, Zhu W, Sartor RB, Boedeker EC, Harpaz N, Pace NR, Li E

Publikováno v: Inflammatory bowel diseases [Inflamm Bowel Dis] 2011 Jan; Vol. 17 (1), pp. 179-84. Date of Electronic Publication: 2010 Sep 13.

Carcinoembryonic antigen in metastatic colorectal cancer.

Autor: Hamm CM; Ottawa Regional Cancer Centre, Ont., Cripps C

Publikováno v: Clinical and investigative medicine. Medecine clinique et experimentale [Clin Invest Med] 1998 Aug-Oct; Vol. 21 (4-5), pp. 186-91.