Zobrazeno 1 - 10
of 221
pro vyhledávání: '"CM Deane"'
Autor:
E Richardson, Š Binter, M Kosmac, M Ghraichy, V von Niederhausern, A Kovaltsuk, J Galson, J Trück, DF Kelly, CM Deane, P Kellam, SJ Watson
Publikováno v:
eLife. 12
Immunoglobulin loci-transgenic animals are widely used in antibody discovery and increasingly in vaccine response modelling. In this study, we phenotypically characterised B-cell populations from the Intelliselect® Transgenic mouse (Kymouse) demonst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ae9cec0a6c403228f88dc2a3dcf9bfd
https://doi.org/10.7554/elife.81629
https://doi.org/10.7554/elife.81629
Autor:
Huhn A; Sir William Dunn School of Pathology, University of Oxford, Oxford, UK., Nissley D; Oxford Protein Informatics Group, Department of Statistics, University of Oxford, Oxford, UK., Wilson DB; Sir William Dunn School of Pathology, University of Oxford, Oxford, UK.; Department of Mathematics and Statistics, Boston University, Boston, Massachusetts, USA.; Kirby Institute, University of New South Wales, Sydney, New South Wales, Australia., Kutuzov MA; Sir William Dunn School of Pathology, University of Oxford, Oxford, UK., Donat R; MRC Translate Immune Discovery Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK., Tan TK; MRC Translate Immune Discovery Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK., Zhang Y; Department of Mathematics and Statistics, Boston University, Boston, Massachusetts, USA.; Department of Mathematics and Department of Biology, Northeastern University, Boston, Massachusetts, USA., Barton MI; Sir William Dunn School of Pathology, University of Oxford, Oxford, UK., Liu C; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Chinese Academy of Medical Science Oxford Institute, University of Oxford, Oxford, UK., Dejnirattisai W; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Division of Emerging Infectious Disease, Research Department, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkoknoi, Bangkok, Thailand., Supasa P; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Mongkolsapaya J; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Townsend A; MRC Translate Immune Discovery Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.; Chinese Academy of Medical Science Oxford Institute, University of Oxford, Oxford, UK., James W; James & Lillian Martin Centre, Sir William Dunn School of Pathology, University of Oxford, Oxford, UK., Screaton G; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Chinese Academy of Medical Science Oxford Institute, University of Oxford, Oxford, UK.; Oxford University Hospitals NHS Foundation Trust, Oxford, Oxford, UK., van der Merwe PA; Sir William Dunn School of Pathology, University of Oxford, Oxford, UK., Deane CM; Oxford Protein Informatics Group, Department of Statistics, University of Oxford, Oxford, UK. deane@stats.ox.ac.uk., Isaacson SA; Department of Mathematics and Statistics, Boston University, Boston, Massachusetts, USA. isaacsas@bu.edu., Dushek O; Sir William Dunn School of Pathology, University of Oxford, Oxford, UK. omer.dushek@path.ox.ac.uk.
Publikováno v:
Nature communications [Nat Commun] 2025 Jan 02; Vol. 16 (1), pp. 338. Date of Electronic Publication: 2025 Jan 02.
Autor:
Ellmen I; Department of Statistics, University of Oxford, Oxford, UK., Raybould MIJ; Department of Statistics, University of Oxford, Oxford, UK., Deane CM; Department of Statistics, University of Oxford, Oxford, UK. deane@stats.ox.ac.uk.
Publikováno v:
Nature chemical biology [Nat Chem Biol] 2025 Jan; Vol. 21 (1), pp. 27-28.
Autor:
Cutting D; Exscientia, Oxford Science Park, Oxford, UK., Dreyer FA; Exscientia, Oxford Science Park, Oxford, UK., Errington D; Exscientia, Oxford Science Park, Oxford, UK., Schneider C; Exscientia, Oxford Science Park, Oxford, UK., Deane CM; Exscientia, Oxford Science Park, Oxford, UK.; Department of Statistics, University of Oxford, Oxford, UK.
Publikováno v:
Journal of computational biology : a journal of computational molecular cell biology [J Comput Biol] 2024 Dec 27. Date of Electronic Publication: 2024 Dec 27.
Autor:
Kenlay H; Exscientia, Oxford Science Park, Oxford, United Kingdom., Dreyer FA; Exscientia, Oxford Science Park, Oxford, United Kingdom., Kovaltsuk A; Exscientia, Oxford Science Park, Oxford, United Kingdom., Miketa D; Exscientia, Oxford Science Park, Oxford, United Kingdom., Pires D; Exscientia, Oxford Science Park, Oxford, United Kingdom., Deane CM; Exscientia, Oxford Science Park, Oxford, United Kingdom.; Department of Statistics, University of Oxford, Oxford, United Kingdom.
Publikováno v:
PLoS computational biology [PLoS Comput Biol] 2024 Dec 06; Vol. 20 (12), pp. e1012646. Date of Electronic Publication: 2024 Dec 06 (Print Publication: 2024).
Autor:
McMaster B; Koohy Lab, Medical Research Council Translational Immune Discovery Unit (MRC TIDU), Weatherall Institute of Molecular Medicine (WIMM), Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom.; Oxford Protein Informatics Group, Department of Statistics, University of Oxford, Oxford, United Kingdom., Thorpe CJ; Open Targets, Wellcome Genome Campus, Hinxton, United Kingdom.; European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, United Kingdom., Rossjohn J; Rossjohn Lab, Infection and Immunity Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Melbourne, VIC, Australia.; Rossjohn Lab, Institute of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, United Kingdom., Deane CM; Oxford Protein Informatics Group, Department of Statistics, University of Oxford, Oxford, United Kingdom., Koohy H; Koohy Lab, Medical Research Council Translational Immune Discovery Unit (MRC TIDU), Weatherall Institute of Molecular Medicine (WIMM), Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom.
Publikováno v:
Frontiers in immunology [Front Immunol] 2024 Dec 02; Vol. 15, pp. 1491656. Date of Electronic Publication: 2024 Dec 02 (Print Publication: 2024).
Autor:
Riccabona JR; Center for Molecular Biosciences Innsbruck, Department of General, Inorganic and Theoretical Chemistry, University of Innsbruck, Innsbruck, Austria., Spoendlin FC; Oxford Protein Informatics Group, Department of Statistics, University of Oxford, Oxford OX1 3LB, UK., Fischer AM; Center for Molecular Biosciences Innsbruck, Department of General, Inorganic and Theoretical Chemistry, University of Innsbruck, Innsbruck, Austria., Loeffler JR; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA., Quoika PK; Center for Functional Protein Assemblies, Technical University of Munich, Ernst-Otto-Fischer-Str. 8, 85748 Garching, Germany., Jenkins TP; Department of Biotechnology and Biomedicine, Technical University of Denmark, DK-2800 Kongens Lyngby, Denmark., Ferguson JA; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA., Smorodina E; Department of Immunology, University of Oslo, Oslo, Norway., Laustsen AH; Department of Biotechnology and Biomedicine, Technical University of Denmark, DK-2800 Kongens Lyngby, Denmark., Greiff V; Department of Immunology, University of Oslo, Oslo, Norway., Forli S; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA., Ward AB; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA. Electronic address: andrew@scripps.edu., Deane CM; Oxford Protein Informatics Group, Department of Statistics, University of Oxford, Oxford OX1 3LB, UK. Electronic address: deane@stats.ox.ac.uk., Fernández-Quintero ML; Center for Molecular Biosciences Innsbruck, Department of General, Inorganic and Theoretical Chemistry, University of Innsbruck, Innsbruck, Austria; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA; Department of Biotechnology and Biomedicine, Technical University of Denmark, DK-2800 Kongens Lyngby, Denmark. Electronic address: mfernandez@scripps.edu.
Publikováno v:
Structure (London, England : 1993) [Structure] 2024 Nov 07; Vol. 32 (11), pp. 2147-2159.e2. Date of Electronic Publication: 2024 Sep 26.
Autor:
Turnbull OM; Department of Statistics, University of Oxford, Oxford, OX1 3LB, United Kingdom., Oglic D; Centre for AI, Biopharmaceuticals R&D, AstraZeneca, Cambridge, CB2 0AA, United Kingdom., Croasdale-Wood R; Biologics Engineering, Oncology R&D, AstraZeneca, Cambridge, CB2 0AA, United Kingdom., Deane CM; Department of Statistics, University of Oxford, Oxford, OX1 3LB, United Kingdom.
Publikováno v:
Bioinformatics (Oxford, England) [Bioinformatics] 2024 Nov 01; Vol. 40 (11).
Autor:
Erasmus MF; Specifica LLC, an IQVIA business, Santa Fe, USA. mfrank.erasmus@iqvia.com., Spector L; Specifica LLC, an IQVIA business, Santa Fe, USA., Ferrara F; Specifica LLC, an IQVIA business, Santa Fe, USA., DiNiro R; Specifica LLC, an IQVIA business, Santa Fe, USA., Pohl TJ; Specifica LLC, an IQVIA business, Santa Fe, USA., Perea-Schmittle K; Specifica LLC, an IQVIA business, Santa Fe, USA., Wang W; University of California, San Diego, USA., Tessier PM; University of Michigan, Ann Arbor, USA., Richardson C; GENEWIZ from Azenta Life Sciences, South Plainfield, USA., Turner L; GENEWIZ from Azenta Life Sciences, South Plainfield, USA., Kumar S; GENEWIZ from Azenta Life Sciences, South Plainfield, USA., Bedinger D; Carterra, Salt Lake City, USA., Sormanni P; University of Cambridge, Cambridge, UK., Fernández-Quintero ML; Scripps Research Institute, San Diego, CA, USA., Ward AB; Scripps Research Institute, San Diego, CA, USA., Loeffler JR; Scripps Research Institute, San Diego, CA, USA., Swanson OM; Scripps Research Institute, San Diego, CA, USA., Deane CM; University of Oxford, Oxford, UK., Raybould MIJ; University of Oxford, Oxford, UK., Evers A; Merck KGaA, Darmstadt, Germany., Sellmann C; Merck KGaA, Darmstadt, Germany., Bachas S; Evolutionary Scale, San Francisco, USA., Ruffolo J; Profluent Bio, Berkeley, USA., Nastri HG; Incyte, Inc, Wilmington, USA., Ramesh K; Incyte, Inc, Wilmington, USA., Sørensen J; OpenEye, Cadence Molecular Sciences, Santa Fe, USA., Croasdale-Wood R; Astrazeneca, Cambridge, UK., Hijano O; Sanofi, Inc, Cambridge, USA., Leal-Lopes C; Sanofi, Inc, Cambridge, USA., Shahsavarian M; Eli Lilly, San Diego, USA., Qiu Y; Sanofi, Inc, Cambridge, USA., Marcatili P; Novo Nordisk, A/S, Bagsværd, Denmark., Vernet E; Novo Nordisk, A/S, Bagsværd, Denmark., Akbar R; Novo Nordisk, A/S, Bagsværd, Denmark., Friedensohn S; Alloy Therapeutics, Basel, Switzerland., Wagner R; Bonito Biosciences, Waltham, USA., Kurella VB; Takeda, Inc, Cambridge, USA., Malhotra S; Takeda, Inc, Cambridge, USA., Kumar S; Takeda, Inc, Cambridge, USA., Kidger P; Cradle Bio, Zürich, Switzerland., Almagro JC; GlobalBio, Inc., Cambridge, MA, USA., Furfine E; Mosaic Biosciences, Boulder, USA., Stanton M; Mosaic Biosciences, Boulder, USA., Graff CP; Mosaic Biosciences, Boulder, USA., Villalba SD; Bayer AG, Leverkusen, Germany., Tomszak F; Bayer AG, Leverkusen, Germany., Teixeira AAR; Institute for Protein Innovation, Boston, USA., Hopkins E; Sapidyne Instruments, Inc. & GmbH, Boise, USA., Dovner M; Sapidyne Instruments, Inc. & GmbH, Boise, USA., D'Angelo S; Specifica LLC, an IQVIA business, Santa Fe, USA., Bradbury ARM; Specifica LLC, an IQVIA business, Santa Fe, USA. andrew.bradbury@iqvia.com.
Publikováno v:
Nature biotechnology [Nat Biotechnol] 2024 Nov; Vol. 42 (11), pp. 1637-1642.
Autor:
Olsen TH; Department of Statistics, University of Oxford, Oxford OX1 3LB, United Kingdom.; GSK Medicines Research Centre, GSK, Stevenage SG1 2NY, United Kingdom., Moal IH; GSK Medicines Research Centre, GSK, Stevenage SG1 2NY, United Kingdom., Deane CM; Department of Statistics, University of Oxford, Oxford OX1 3LB, United Kingdom.
Publikováno v:
Bioinformatics (Oxford, England) [Bioinformatics] 2024 Nov 01; Vol. 40 (11).