Zobrazeno 1 - 10
of 62
pro vyhledávání: '"CM, conditioned medium"'
Autor:
Harsh Maan, Tatyana L. Povolotsky, Ziv Porat, Maxim Itkin, Sergey Malitsky, Ilana Kolodkin-Gal
Publikováno v:
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 20, Iss, Pp 15-25 (2022)
Computational and Structural Biotechnology Journal, Vol 20, Iss, Pp 15-25 (2022)
Graphical abstract
In nature, bacteria frequently reside in differentiated communities or biofilms. These multicellular communities are held together by self-produced polymers that allow the community members to adhere to the surface as well as
In nature, bacteria frequently reside in differentiated communities or biofilms. These multicellular communities are held together by self-produced polymers that allow the community members to adhere to the surface as well as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb0476cabf974802547e035f5d18c5d0
http://europepmc.org/articles/PMC8666610
http://europepmc.org/articles/PMC8666610
Autor:
Kenji Izumi, Nyein Nyein Chan, Jun-ichi Tanuma, Satoshi Maruyama, Kenta Haga, Masami Kawaharada, Manabu Yamazaki, Ayako Suzuki, Toshihiko Mikami, Tadaharu Kobayashi, Emi Hoshikawa, Akinori Funayama
Publikováno v:
Translational Oncology, Vol 14, Iss 12, Pp 101236-(2021)
Translational Oncology
Translational Oncology
Highlights • TGF-β1 secreted from CAFs promote the migration and invasion of OSCC cells. • CAFs upregulate SOX9 expression of OSCC cells, possibly through inducing EMT. • The presence of CAFs is correlated with SOX9 expression in the invasive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f37e513d06f9e4f0bfec369f2e664e8f
http://www.sciencedirect.com/science/article/pii/S193652332100228X
http://www.sciencedirect.com/science/article/pii/S193652332100228X
Publikováno v:
Translational Oncology, Vol 14, Iss 12, Pp 101231-(2021)
Translational Oncology
Translational Oncology
Highlights • EVs mediate the interaction between tumor and stromal cells in the TME. • Tumors mediate CAF-like activation of stromal cells through EVs. • CAF-derived EVs promote tumor proliferation, metastasis and therapeutic resistance.
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Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc5dbb220f9849b850d3378d75eced1b
http://www.sciencedirect.com/science/article/pii/S1936523321002230
http://www.sciencedirect.com/science/article/pii/S1936523321002230
Autor:
Wang, Chunying, Xu, Siran, Tian, Yang, Ju, Anji, Hou, Qiaoyun, Liu, Jie, Fu, Yan, Luo, Yongzhang
Publikováno v:
Neoplasia (New York, N.Y.)
Tumor lymphangiogenesis has been previously documented to predict regional lymph node metastasis and promote the spread to distant organs. However, the underlying mechanism initiating tumor lymphangiogenesis remains unclear. Here we described a novel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a6243be948ab41d95728cee452c7f99d
http://europepmc.org/articles/PMC6439287
http://europepmc.org/articles/PMC6439287
Autor:
Shengbing Yang, Hanjun Li, Jingtian Mei, Han Qiao, Feng Zhou, Minqi Wang, Linyang Chu, Tingting Tang, Xiuguo Han
Publikováno v:
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 9, Iss 5, Pp 973-985 (2019)
Acta Pharmaceutica Sinica B, Vol 9, Iss 5, Pp 973-985 (2019)
The objective was to investigate the effect of kinsenoside (Kin) treatments on macrophage polarity and evaluate the resulting protection of chondrocytes to attenuate osteoarthritis (OA) progression. RAW264.7 macrophages were polarized to M1/M2 subtyp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::657da9eb0531d9727733222372f40b72
http://europepmc.org/articles/PMC6804452
http://europepmc.org/articles/PMC6804452
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 7, Iss 4, Pp 783-802 (2019)
Cellular and Molecular Gastroenterology and Hepatology, Vol 7, Iss 4, Pp 783-802 (2019)
Background & Aims Intratumor heterogeneity is a common feature of colorectal cancer (CRC). Here, we analyzed whether mesenchymal-like CRC cells promote the progression of epithelial-like CRC cells via paracrine mechanisms. Methods Six CRC cell lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7d68c66508b0f4fbdd52651a7e4ecc9
https://doi.org/10.1016/j.jcmgh.2019.02.003
https://doi.org/10.1016/j.jcmgh.2019.02.003
Publikováno v:
JID Innovations
JID Innovations, Vol 1, Iss 2, Pp 100017-(2021)
JID Innovations, Vol 1, Iss 2, Pp 100017-(2021)
As the major cell surface receptors for the extracellular matrix, integrins regulate adhesion and migration and have been shown to drive tumor growth and progression. Previous studies showed that mice lacking integrin α3β1 in the epidermis fail to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3c6bde38423be27b5db85ec7b184beb
http://europepmc.org/articles/PMC8659409
http://europepmc.org/articles/PMC8659409
Publikováno v:
Cytokine & Growth Factor Reviews
Highlights • SARS-CoV-2 can infect multiple organs leading to their dysfunction, so a pleiotropic therapy would be advantageous. • MSC: MSC can simultaneously address injuries in multiple organs and promote their repair. • MSC, immunomodulators
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9255591c844c585ae46eaffae5402fbe
Autor:
Masahiro Hiasa, Tatsuo Okui, Toshiyuki Yoneda, Shoji Ryumon, Yuki Kunisada, Akira Sasaki, Fletcher A. White, Kisho Ono, Soichiro Ibaragi, G. David Roodman
Publikováno v:
Journal of Bone Oncology
Journal of Bone Oncology, Vol 26, Iss, Pp 100330-(2021)
Journal of Bone Oncology, Vol 26, Iss, Pp 100330-(2021)
Graphical abstract
Highlights • The 4T1 mouse breast cancer injected in tibiae induced bone pain. • The 4T1 breast cancer secreted high mobility group box 1 (HMGB1) that promotes axogenesis of sensory neurons. • Bone pain was reduced by HM
Highlights • The 4T1 mouse breast cancer injected in tibiae induced bone pain. • The 4T1 breast cancer secreted high mobility group box 1 (HMGB1) that promotes axogenesis of sensory neurons. • Bone pain was reduced by HM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f17a393c06015aa4d42c1408b903e0bb
http://ir.lib.shimane-u.ac.jp/54137
http://ir.lib.shimane-u.ac.jp/54137
Macrophage MerTK promotes profibrogenic cross-talk with hepatic stellate cells via soluble mediators
Autor:
Mirella Pastore, Alessandra Caligiuri, Chiara Raggi, Nadia Navari, Benedetta Piombanti, Giovanni Di Maira, Elisabetta Rovida, Marie-Pierre Piccinni, Letizia Lombardelli, Federica Logiodice, Krista Rombouts, Salvatore Petta, Fabio Marra
Publikováno v:
JHEP Reports. 4:100444
Background & aims: Activation of Kupffer cells and recruitment of monocytes are key events in fibrogenesis. These cells release soluble mediators which induce the activation of hepatic stellate cells (HSCs), the main fibrogenic cell type within the l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4426fd2abba675fb27730b5800bb5cc
https://doi.org/10.1016/j.jhepr.2022.100444
https://doi.org/10.1016/j.jhepr.2022.100444