Sonic hedgehog signaling facilitates pyroptosis in mouse heart following ischemia/reperfusion via enhancing the formation of CARD10-BCL10-MALT1 complex.

Autor: Li MR; Department of Pharmacology, Xiangya School of Pharmaceutical Sciences, Central South University, Changsha, 410078, China; Hunan Provincial Key Laboratory of Cardiovascular Research, Xiangya School of Pharmaceutical Sciences, Central South University, Changsha, 410078, China., Lu LQ; Department of Pharmacology, Xiangya School of Pharmaceutical Sciences, Central South University, Changsha, 410078, China; Hunan Provincial Key Laboratory of Cardiovascular Research, Xiangya School of Pharmaceutical Sciences, Central South University, Changsha, 410078, China., Zhang YY; Department of Pharmacology, Xiangya School of Pharmaceutical Sciences, Central South University, Changsha, 410078, China; Hunan Provincial Key Laboratory of Cardiovascular Research, Xiangya School of Pharmaceutical Sciences, Central South University, Changsha, 410078, China., Yao BF; Department of Pharmacology, Xiangya School of Pharmaceutical Sciences, Central South University, Changsha, 410078, China; Hunan Provincial Key Laboratory of Cardiovascular Research, Xiangya School of Pharmaceutical Sciences, Central South University, Changsha, 410078, China., Tang C; Department of Pharmacology, Xiangya School of Pharmaceutical Sciences, Central South University, Changsha, 410078, China; Hunan Provincial Key Laboratory of Cardiovascular Research, Xiangya School of Pharmaceutical Sciences, Central South University, Changsha, 410078, China., Dai SY; Department of Pharmacology, Xiangya School of Pharmaceutical Sciences, Central South University, Changsha, 410078, China; Hunan Provincial Key Laboratory of Cardiovascular Research, Xiangya School of Pharmaceutical Sciences, Central South University, Changsha, 410078, China., Luo XJ; Department of Laboratory Medicine, The Third Xiangya Hospital of Central South University, Changsha, 410013, China. Electronic address: xjluo22@csu.edu.cn., Peng J; Department of Pharmacology, Xiangya School of Pharmaceutical Sciences, Central South University, Changsha, 410078, China; Hunan Provincial Key Laboratory of Cardiovascular Research, Xiangya School of Pharmaceutical Sciences, Central South University, Changsha, 410078, China. Electronic address: junpeng@csu.edu.cn.

Publikováno v: European journal of pharmacology [Eur J Pharmacol] 2024 Dec 05; Vol. 984, pp. 177019. Date of Electronic Publication: 2024 Sep 27.

Study of individual domains contributing to MALT1 dimerization in BCL10-independent and dependent assembly.

Autor: Kuo BJ; Department of Biotechnology and Bioindustry Sciences, College of Bioscience and Biotechnology, National Cheng Kung University, Tainan, 70101, Taiwan., Lin SC; Genomics Research Center, Academia Sinica, Taipei, Taiwan., Tu YF; Department of Biotechnology and Bioindustry Sciences, College of Bioscience and Biotechnology, National Cheng Kung University, Tainan, 70101, Taiwan; Genomics Research Center, Academia Sinica, Taipei, Taiwan., Huang PH; Department of Biotechnology and Bioindustry Sciences, College of Bioscience and Biotechnology, National Cheng Kung University, Tainan, 70101, Taiwan., Lo YC; Department of Biotechnology and Bioindustry Sciences, College of Bioscience and Biotechnology, National Cheng Kung University, Tainan, 70101, Taiwan. Electronic address: gracelo@ncku.edu.tw.

Publikováno v: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2024 Jul 12; Vol. 717, pp. 150029. Date of Electronic Publication: 2024 Apr 29.

USP9X-mediated deubiquitination of B-cell CLL/lymphoma 9 potentiates Wnt signaling and promotes breast carcinogenesis

Autor: Shang, Zesen, Zhao, Jiao, Zhang, Qi, Cao, Cheng, Tian, Shanshan, Zhang, Kai, Liu, Ling, Shi, Lei, Yu, Na, Yang, Shangda

Publikováno v: In Journal of Biological Chemistry 21 June 2019 294(25):9844-9857

Do genetic polymorphisms of B-cell CLL/lymphoma 2 confer susceptibility to anti-tuberculous therapy-associated drug-induced liver injury?

Autor: Mengyuan Lyu, Lin Jiao, Jian Zhou, Haijun Li, Zirui Meng, Wanhong Xie, Jing Ren, Qin Bian, Binwu Ying

Publikováno v: International Journal of Infectious Diseases, Vol 91, Iss , Pp 223-231 (2020)

Objectives: The aim of this study was to identify the relationship between B-cell CLL/lymphoma 2 (BCL2) polymorphisms and susceptibility to anti-tuberculous therapy-associated drug-induced liver injury (ATT-DILI). Methods: A total of 746 tuberculosis

Externí odkaz: https://doaj.org/article/937d2eec7f154320bcf504c9e26b501e

Bcl10 phosphorylation-dependent droplet-like condensation positively regulates DNA virus-induced innate immune signaling.

Autor: Yang D; Institute for Immunology, School of Medicine, Tsinghua University, Beijing, 100084, China., Pei G; Beijing Advanced Innovation Center for Structural Biology, School of Life Sciences, Tsinghua University, Beijing, 100084, China.; Tsinghua-Peking Center for Life Sciences, Beijing, 100084, China., Dong S; Beijing Advanced Innovation Center for Structural Biology, School of Life Sciences, Tsinghua University, Beijing, 100084, China.; Tsinghua-Peking Center for Life Sciences, Beijing, 100084, China., Zhang W; MOE Key Laboratory of Bioinformatics, School of Life Sciences, Tsinghua University, Beijing, 100084, China., Deng H; MOE Key Laboratory of Bioinformatics, School of Life Sciences, Tsinghua University, Beijing, 100084, China., Zhao X; Institute for Immunology, School of Medicine, Tsinghua University, Beijing, 100084, China., Li P; Beijing Advanced Innovation Center for Structural Biology, School of Life Sciences, Tsinghua University, Beijing, 100084, China.; Tsinghua-Peking Center for Life Sciences, Beijing, 100084, China., Lin X; Institute for Immunology, School of Medicine, Tsinghua University, Beijing, 100084, China. linxin307@mail.tsinghua.edu.cn.; Tsinghua-Peking Center for Life Sciences, Beijing, 100084, China. linxin307@mail.tsinghua.edu.cn.

Publikováno v: Science China. Life sciences [Sci China Life Sci] 2023 Feb; Vol. 66 (2), pp. 283-297. Date of Electronic Publication: 2022 Sep 15.