Zobrazeno 1 - 10
of 51
pro vyhledávání: '"CLEMENS GIESSEN-JUNG"'
Autor:
Annika Kurreck, Volker Heinemann, Ludwig Fischer von Weikersthal, Thomas Decker, Florian Kaiser, Jens Uhlig, Michael Schenk, Jens Freiberg-Richter, Bettina Peuser, Claudio Denzlinger, Ullrich Graeven, Kathrin Heinrich, Swantje Held, Arndt Stahler, Annabel Helga Sophie Alig, Ivan Jelas, Jobst C. von Einem, Sebastian Stintzing, Clemens Giessen-Jung, Dominik P. Modest
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
IntroductionEarly tumor shrinkage (ETS), depth of response (DpR), and time to DpR represent exploratory endpoints that may serve as early efficacy parameters and predictors of long-term outcome in metastatic colorectal cancer (mCRC). We analyzed thes
Externí odkaz:
https://doaj.org/article/02c58eab2dbe4e41985915f0822765da
Autor:
KLARA DORMAN, DANMEI ZHANG, WOLFGANG G. KUNZ, MARTIN ANGELE, JENS NEUMANN, ALEXANDER BURGES, MICHAEL VON BERGWELT-BAILDON, VOLKER HEINEMANN, STEFAN BOECK, CLEMENS GIESSEN-JUNG
Publikováno v:
Anticancer Research. 43:1857-1861
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3eeba7826cd0846a10a6c18484fb3d60
https://doi.org/10.21873/anticanres.16340
https://doi.org/10.21873/anticanres.16340
Autor:
Thilo Westhofen, Lennert Eismann, Alexander Buchner, Boris Schlenker, Clemens Giessen-Jung, Armin Becker, Christian G. Stief, Alexander Kretschmer
Publikováno v:
European Urology Focus. 8:1659-1665
It has been shown that baseline health-related quality of life (HRQOL) is a valuable prognostic indicator of survival outcomes for various metastatic cancers, but there is no evidence on the prognostic value of baseline HRQOL for patients with bladde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c9391d8af818b2521c91d883bc5ae73
https://doi.org/10.1016/j.euf.2022.02.001
https://doi.org/10.1016/j.euf.2022.02.001
Autor:
Michael Ruzicka, Sonja Wurm, Lars Lindner, Martin Dreyling, Michael von Bergwelt-Baildon, Stefan Boeck, Clemens Giessen-Jung, Valeria Milani, Joachim H. Stemmler, Marion Subklewe, Oliver Weigert, Karsten Spiekermann
Publikováno v:
Infection. 51:231-238
Purpose Following the emergency use authorization of BNT162b2 by the Food and Drug administration (FDA) in early December 2020, mRNA- and vector-based vaccines became an important means of reducing the spread and mortality of the COVID-19 pandemic. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f76f85961bba99b1eb21fd6efae399c
https://doi.org/10.1007/s15010-022-01909-5
https://doi.org/10.1007/s15010-022-01909-5
Autor:
Laura E. Fischer, Sebastian Stintzing, Ludwig Fischer von Weikersthal, Dominik P. Modest, Thomas Decker, Alexander Kiani, Florian Kaiser, Salah-Eddin Al-Batran, Tobias Heintges, Christian Lerchenmüller, Christoph Kahl, Gernot Seipelt, Frank Kullmann, Martina Stauch, Werner Scheithauer, Clemens Giessen-Jung, Jens Uhlig, Bettina Peuser, Claudio Denzlinger, Arndt Stahler, Lena Weiss, Kathrin Heinrich, Swantje Held, Andreas Jung, Thomas Kirchner, Volker Heinemann
Publikováno v:
British Journal of Cancer. 127:836-843
Summary Background The evidence on the efficacy of anticancer therapy is limited in older patients with metastatic colorectal cancer (mCRC). This retrospective analysis of phase III FIRE-3 trial assesses the efficacy of FOLFIRI plus either cetuximab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a68edabca01df58b33a3611c4acafc2
https://doi.org/10.1038/s41416-022-01854-y
https://doi.org/10.1038/s41416-022-01854-y
Autor:
Volker Heinemann, Andreas Jung, Thomas Kirchner, Jens Neumann, Markus Moehler, Thomas Decker, Swantje Held, Alexander Kiani, Martina Stauch, Andreas Schalhorn, Nicolas Moosmann, Ludwig Fischer von Weikersthal, Florian Kaiser, Boryana Ivanova, Christine Kapaun, Clemens Giessen-Jung, Ingrid Ricard, Dominik P. Modest, Sebastian Stintzing, Arndt Stahler
Normalized AREG expression according to baseline characteristics.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20a2910e5897433cb240746743a6d8e1
https://doi.org/10.1158/1078-0432.22476938
https://doi.org/10.1158/1078-0432.22476938
Autor:
Volker Heinemann, Andreas Jung, Thomas Kirchner, Jens Neumann, Markus Moehler, Thomas Decker, Swantje Held, Alexander Kiani, Martina Stauch, Andreas Schalhorn, Nicolas Moosmann, Ludwig Fischer von Weikersthal, Florian Kaiser, Boryana Ivanova, Christine Kapaun, Clemens Giessen-Jung, Ingrid Ricard, Dominik P. Modest, Sebastian Stintzing, Arndt Stahler
Outcome according to high vs. low unnormalized AREG expression in all patients and subgroups
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41829af0bb1ad893d90f8cb3597f0079
https://doi.org/10.1158/1078-0432.22476932
https://doi.org/10.1158/1078-0432.22476932
Autor:
Volker Heinemann, Andreas Jung, Thomas Kirchner, Jens Neumann, Markus Moehler, Thomas Decker, Swantje Held, Alexander Kiani, Martina Stauch, Andreas Schalhorn, Nicolas Moosmann, Ludwig Fischer von Weikersthal, Florian Kaiser, Boryana Ivanova, Christine Kapaun, Clemens Giessen-Jung, Ingrid Ricard, Dominik P. Modest, Sebastian Stintzing, Arndt Stahler
Purpose:Amphiregulin (AREG) and epiregulin (EREG) are ligands of EGFR. Predictive information for anti-EGFR treatment in metastatic colorectal cancer (mCRC) was observed, but data for other agents is limited.Experimental Design:Ligand mRNA expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52050a7f74cba65dfcd8f207d1d8d346
https://doi.org/10.1158/1078-0432.c.6529532.v1
https://doi.org/10.1158/1078-0432.c.6529532.v1
Autor:
Volker Heinemann, Andreas Jung, Thomas Kirchner, Jens Neumann, Markus Moehler, Thomas Decker, Swantje Held, Alexander Kiani, Martina Stauch, Andreas Schalhorn, Nicolas Moosmann, Ludwig Fischer von Weikersthal, Florian Kaiser, Boryana Ivanova, Christine Kapaun, Clemens Giessen-Jung, Ingrid Ricard, Dominik P. Modest, Sebastian Stintzing, Arndt Stahler
Univariate and multivariate Cox regression analyses for overall and progression-free survival in all patients.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29eeaf1c1ffd6093702b6991bb323397
https://doi.org/10.1158/1078-0432.22476935.v1
https://doi.org/10.1158/1078-0432.22476935.v1
Autor:
Volker Heinemann, Andreas Jung, Thomas Kirchner, Jens Neumann, Markus Moehler, Thomas Decker, Swantje Held, Alexander Kiani, Martina Stauch, Andreas Schalhorn, Nicolas Moosmann, Ludwig Fischer von Weikersthal, Florian Kaiser, Boryana Ivanova, Christine Kapaun, Clemens Giessen-Jung, Ingrid Ricard, Dominik P. Modest, Sebastian Stintzing, Arndt Stahler
Forest plot of individual trial analysis of high versus low amphiregulin (AREG) mRNA expression dichotomized by median and 3rd quartile showing (A) hazard ratios (HR) and 95% confidence interval (95% CI) for overall survival and (B) hazard ratios (HR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c98fb65c2d3910c8c90c66910d47394
https://doi.org/10.1158/1078-0432.22476941
https://doi.org/10.1158/1078-0432.22476941