Zobrazeno 1 - 10
of 154
pro vyhledávání: '"CLEC9A"'
Akademický článek
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Autor:
M. H. Lahoud, K. J. Radford
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 18, Iss 1 (2022)
Dendritic cell (DC) vaccines are a safe and effective means of inducing tumor immune responses, however, a better understanding of DC biology is required in order to realize their full potential. Recent advances in DC biology have identified a crucia
Externí odkaz:
https://doaj.org/article/022a2850a236451f99387f1d4bde5834
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
PurposeAbnormal CLEC9A expression is concerned with carcinogenesis. However, the role of CLEC9A in lung adenocarcinoma (LUAD) remains unknown. The goal of this study was to reveal the role of CLEC9A in LUAD based on bioinformatics and cellular functi
Externí odkaz:
https://doaj.org/article/0e34f00744e34f14a2dc4dbf41c126d9
Publikováno v:
Frontiers in Immunology, Vol 10 (2020)
DNGR-1 (encoded by CLEC9A) is a C-type lectin receptor (CLR) with an expression profile that is mainly restricted to type 1 conventional dendritic cells (cDC1s) both in mice and humans. This delimited expression pattern makes it appropriate for defin
Externí odkaz:
https://doaj.org/article/801d0af43fa7413fb144877f2dc2d16b
Autor:
Frances E Pearson, Kirsteen M Tullett, Ingrid M Leal‐Rojas, Oscar L Haigh, Kelly‐Anne Masterman, Carina Walpole, John S Bridgeman, James E McLaren, Kristin Ladell, Kelly Miners, Sian Llewellyn‐Lacey, David A Price, Antje Tunger, Marc Schmitz, John J Miles, Mireille H Lahoud, Kristen J Radford
Publikováno v:
Clinical & Translational Immunology, Vol 9, Iss 6, Pp n/a-n/a (2020)
Abstract Objectives Vaccines that prime Wilms' tumor 1 (WT1)‐specific CD8+ T cells are attractive cancer immunotherapies. However, immunogenicity and clinical response rates may be enhanced by delivering WT1 to CD141+ dendritic cells (DCs). The C
Externí odkaz:
https://doaj.org/article/d7716a6649ca41f9a6290ec9da9eae79
Autor:
Jack D Chan, Bianca vonScheidt, Bijun Zeng, Amanda J Oliver, Ashleigh S Davey, Aesha I Ali, Ranjeny Thomas, Joseph A Trapani, Phillip K Darcy, Michael H Kershaw, Riccardo Dolcetti, Clare Y Slaney
Publikováno v:
Clinical & Translational Immunology, Vol 9, Iss 7, Pp n/a-n/a (2020)
Abstract Objectives Adoptive transfer of chimeric antigen receptor (CAR)‐modified T cells is a form of cancer immunotherapy that has achieved remarkable efficacy in patients with some haematological cancers. However, challenges remain in CAR T‐ce
Externí odkaz:
https://doaj.org/article/fcf8f427b57d41fd96ae5a6361cd0f8b
Autor:
Emily Gwyer Findlay, Andrew J. Currie, Ailiang Zhang, Jana Ovciarikova, Lisa Young, Holly Stevens, Brian J. McHugh, Marta Canel, Mohini Gray, Simon W.F. Milling, John D.M. Campbell, John Savill, Alan Serrels, Donald J. Davidson
Publikováno v:
OncoImmunology, Vol 8, Iss 8 (2019)
Immunization of patients with autologous, ex vivo matured dendritic cell (DC) preparations, in order to prime antitumor T-cell responses, is the focus of intense research. Despite progress and approval of clinical approaches, significant enhancement
Externí odkaz:
https://doaj.org/article/8c619a0ba3fa49a6a60740bf5be1c638
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
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Autor:
Raphaël Mattiuz, Christian Wohn, Sonia Ghilas, Marc Ambrosini, Yannick O. Alexandre, Cindy Sanchez, Anissa Fries, Thien-Phong Vu Manh, Bernard Malissen, Marc Dalod, Karine Crozat
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Type 1 conventional DCs (cDC1) excel in the cross-priming of CD8+ T cells, which is crucial for orchestrating efficient immune responses against viruses or tumors. However, our understanding of their physiological functions and molecular regulation h
Externí odkaz:
https://doaj.org/article/b273b8922beb47cebccd18fc34d7b35e
Autor:
Robert Winchester, Alexis Boneparth, Mark Gorelik, Samantha B. Gaines, Peter S. Dayan, Mateo L. Amezcua, Janice J. Huang, Tamar R. Lubell, Marissa Dale, Mark D. Hicar
Publikováno v:
The Journal of Allergy and Clinical Immunology
Background Multisystem inflammatory syndrome in children (MIS-C) is an acute, febrile, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-associated syndrome, often with cardiohemodynamic dysfunction. Insight into mechanism of disease is st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af006b9289f4e815206538a729abacc2
https://doi.org/10.1016/j.jaci.2021.10.015
https://doi.org/10.1016/j.jaci.2021.10.015