Antinociceptive antibiotics-loaded into solid lipid nanoparticles of prolonged release: Measuring pharmacological efficiency and time span on chronic monoarthritis rats.

Autor: Carlos Valdes, Gonzalo Bustos, Jose L Martinez, Claudio Laurido

Publikováno v: PLoS ONE, Vol 13, Iss 4, p e0187473 (2018)

Pain is a sensory experience of a complex physiological nature in which is not only involved the nervous system. Among its many features is the development of chronic pain that is more complicated to treat because of the central somatization processe

Externí odkaz: https://doaj.org/article/4e200b3917424b46bcc739725e464912

Antinociceptive Effect of Rat D-Serine Racemase Inhibitors, L-Serine-O-Sulfate, and L-Erythro-3-Hydroxyaspartate in an Arthritic Pain Model

Autor: Claudio Laurido, Alejandro Hernández, Teresa Pelissier, Luis Constandil

Publikováno v: The Scientific World Journal, Vol 2012 (2012)

N-methyl-D-aspartic acid receptor (NMDAr) activation requires the presence of D-serine, synthesized from L-serine by a pyridoxal 5′-phosphate-dependent serine racemase (SR). D-serine levels can be lowered by inhibiting the racemization of L-serine.

Externí odkaz: https://doaj.org/article/5092270c8bb84daba95054dba148e160

Complete essential oils of Laurus nobilis inducing antinociceptive action by opioid mechanism in C-Reflex and spinal Wind-Up model in rat

Autor: Claudio Laurido, Bernardo Morales, Carlos Valdes, Luisauris Jaimes, José Luis Martínez, Raúl Vinet

Publikováno v: Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas. 19:420-427

The essential oil of Laurus nobilis L. was used to test their antinociceptive efficacy. It was applied intraperitoneally (i.p.) to rats subjected to a nociception test (C reflex and spinal wind-up). The results showed that the essential oil applied a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e57f734f3bb8bf122739d38282672de4
https://doi.org/10.37360/blacpma.20.19.4.29

A Review of the Actions of Endogenous and Exogenous Vasoactive Substances during the Estrous Cycle and Pregnancy in Rats

Autor: Raúl Vinet, Bernardo Morales, José L. Martínez, Luisauris Jaimes, Marcela Knox, Claudio Laurido, Julio Benites

Publikováno v: Animals : an Open Access Journal from MDPI
Animals, Vol 9, Iss 6, p 288 (2019)

Simple Summary The vascular endothelium plays an essential role in regulating cardiovascular homeostasis by controlling the vascular tone. However, it is known that variations of sex hormones in the female during the reproductive cycle have a signifi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d2e56511a3648148239eb4f9bbb2bf8
https://pubmed.ncbi.nlm.nih.gov/31146394

Effects of two bisbenzylisoquinoline alkaloids, Antioquine and Tetrandrine, compared to Verapamil in Rat Thoracic Aorta

Autor: José L. Martínez, Raúl Vinet, Harold Gomez, Claudio Laurido, Luisauris Jaimes, Julio Benites, Silvia Vargas-Rueda

Publikováno v: Anais da Academia Brasileira de Ciências, Volume: 90, Issue: 2, Pages: 1459-1463, Published: APR 2018
Anais da Academia Brasileira de Ciências v.90 n.2 2018
Anais da Academia Brasileira de Ciências
Academia Brasileira de Ciências (ABC)
instacron:ABC
Anais da Academia Brasileira de Ciências, Vol 90, Iss 2, Pp 1459-1463

The objective of this study was to compare two alkaloids (antioquine and tetrandrine) with verapamil; knowing that the smooth muscle respond to KCl and relationships with calcium. The effects of antioquine and tetrandrine, was studied in adults Wista

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00a884e8d371dd264687f727829169f5
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652018000401459&lng=en&tlng=en