Zobrazeno 1 - 10
of 145
pro vyhledávání: '"CLAUDIA SISSI"'
Publikováno v:
Photonics, Vol 11, Iss 11, p 1061 (2024)
The analysis of nucleic acid structures, topologies, nano-mechanics and interactions with ligands and other biomacromolecules (most notably proteins) at the single molecule level has become a fundamental topic in molecular biophysics over the last tw
Externí odkaz:
https://doaj.org/article/87be74e746854d0991534e5dddf12a1b
Publikováno v:
Frontiers in Chemistry, Vol 10 (2022)
G-quadruplexes (G4s) are nucleic acid secondary structures detected within human chromosomes, that cluster at gene promoters and enhancers. This suggests that G4s may play specific roles in the regulation of gene expression. Within a distinct subgrou
Externí odkaz:
https://doaj.org/article/1fe8e29107d04ed9b4b871c6a61fa80d
Autor:
Benedetta Fois, Simona Distinto, Rita Meleddu, Serenella Deplano, Elias Maccioni, Costantino Floris, Antonella Rosa, Mariella Nieddu, Pierluigi Caboni, Claudia Sissi, Andrea Angeli, Claudiu T. Supuran, Filippo Cottiglia
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 35, Iss 1, Pp 539-548 (2020)
In an in vitro screening for human carbonic anhydrase (hCA) inhibiting agents from higher plants, the petroleum ether and ethyl acetate extracts of Magydaris pastinacea seeds selectively inhibited hCA IX and hCA XII isoforms. The phytochemical invest
Externí odkaz:
https://doaj.org/article/ba38eeee14924a808934f20776c11ded
Publikováno v:
Pharmaceuticals, Vol 15, Iss 3, p 373 (2022)
In the past two decades, significant efforts have been put into designing small molecules to target selected genomic sites where DNA conformational rearrangements control gene expression. G-rich sequences at oncogene promoters are considered good poi
Externí odkaz:
https://doaj.org/article/be7b308e7f6145ed85ce118636e2c203
Publikováno v:
ARKIVOC, Vol 2004, Iss 5, Pp 204-218 (2004)
Externí odkaz:
https://doaj.org/article/0ed6353e8cb84d809351025d9599f5e4
Autor:
Silvia Da Ros, Eleonora Zorzan, Mery Giantin, Lara Zorro Shahidian, Manlio Palumbo, Mauro Dacasto, Claudia Sissi
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e103876 (2014)
Downregulation of gene expression by induction of non-canonical DNA structures at promotorial level is a novel attractive anticancer strategy. In human, two guanine-rich sequences (h_kit1 and h_kit2) were identified in the promotorial region of oncog
Externí odkaz:
https://doaj.org/article/c047fd252dd2497d96aa64573b5c85dc
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e58529 (2013)
The physiological role(s) played by G-quadruplexes renders these 'non-canonical' DNA secondary structures interesting new targets for therapeutic intervention. In particular, the search for ligands for selective recognition and stabilization of G-qua
Externí odkaz:
https://doaj.org/article/cdb5d662e5814e3ba7389f1523df69bd
Autor:
Michele Ghezzo, Claudia Sissi
Publikováno v:
Journal of Thermal Analysis and Calorimetry. 148:5375-5385
I-motifs are tetra-helixes that may form in cytosine-rich strands. They are based on cytosine–cytosine+ base pairs that require the N3 hemi-protonation of the nucleobases, and therefore, the stability of these non-canonical DNA arrangements depends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2745f8c8509cadbbfe41f80d98f15d4a
https://doi.org/10.1007/s10973-023-12060-0
https://doi.org/10.1007/s10973-023-12060-0
Autor:
Manlio Palumbo, Claudia Sissi
Publikováno v:
Nucleic Acids in Medicinal Chemistry and Chemical Biology. :483-510
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a0fc043ad135da24fb0fee5d697d0d3
https://doi.org/10.1002/9781119692799.ch14
https://doi.org/10.1002/9781119692799.ch14
Autor:
Manlio Palumbo, Claudia Sissi
Publikováno v:
Handbook of Chemical Biology of Nucleic Acids ISBN: 9789811613135
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e80c434d279730806a9f3c27835d4c93
https://doi.org/10.1007/978-981-16-1313-5_39-1
https://doi.org/10.1007/978-981-16-1313-5_39-1
