Zobrazeno 1 - 10
of 18
pro vyhledávání: '"CK19, cytokeratin 19"'
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 4, Pp 973-997 (2021)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims The functions of the liver and the intestine are closely tied in both physiological and pathologic conditions. The gut microbiota (GM) often cause deleterious effects during hepatic pathogenesis. Autophagy is essential for liver hom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5847c5c25a4c55b7146f469ae9e2e369
http://www.sciencedirect.com/science/article/pii/S2352345X20301740
http://www.sciencedirect.com/science/article/pii/S2352345X20301740
Autor:
Megan T. Hoffman, Samantha B. Kemp, Daniel J. Salas-Escabillas, Yaqing Zhang, Nina G. Steele, Stephanie The, Daniel Long, Simone Benitz, Wei Yan, Robert F. Margolskee, Filip Bednar, Marina Pasca di Magliano, Hui-Ju Wen, Howard C. Crawford
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims Pancreatic ductal adenocarcinoma (PDA) initiation and progression are accompanied by an immunosuppressive inflammatory response. Here, we evaluated the immunomodulatory role of chemosensory signaling in metaplastic tuft cells (MTCs)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::686c6a10eefc99372b1badab6334bce4
https://doi.org/10.1016/j.jcmgh.2020.08.011
https://doi.org/10.1016/j.jcmgh.2020.08.011
Autor:
Rumei, Li, Anna, Palmiotti, Hilde D, de Vries, Milaine V, Hovingh, Martijn, Koehorst, Niels L, Mulder, Yue, Zhang, Kim, Kats, Vincent W, Bloks, Jingyuan, Fu, Henkjan J, Verkade, Jan Freark, de Boer, Folkert, Kuipers
Publikováno v:
Journal of Lipid Research
Bile acids (BAs) play important roles in lipid homeostasis, and BA signaling pathways serve as therapeutic targets for nonalcoholic fatty liver disease (NAFLD). Recently, we generated cytochrome P450, family 2, subfamily C, polypeptide 70 (Cyp2c70−
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::df7ace3578bb12b2e9c95e117c5632a6
https://pubmed.ncbi.nlm.nih.gov/34626589
https://pubmed.ncbi.nlm.nih.gov/34626589
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 7, Iss 4, Pp 841-856 (2019)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims The Onecut 1 transcription factor (Oc1, a.k.a. HNF6) promotes differentiation of endocrine and duct cells of the pancreas; however, it has no known role in acinar cell differentiation. We sought to better understand the role of Oc1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8340f4db90d84f348eeb0763345455be
http://www.sciencedirect.com/science/article/pii/S2352345X19300207
http://www.sciencedirect.com/science/article/pii/S2352345X19300207
Autor:
Michelle M. Cooley, Guy E. Groblewski
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 10, Iss 1, Pp 199-200 (2020)
Cellular and Molecular Gastroenterology and Hepatology, Vol 10, Iss 1, Pp 199-200 (2020)
Background & Aims Alcohol abuse is the major cause of experimental and human pancreatitis but the molecular mechanisms remain largely unknown. We investigated the role of transcription factor EB (TFEB), a master regulator of lysosomal biogenesis, in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da83a92c019314da616a48a249cd63ec
http://europepmc.org/articles/PMC7296224
http://europepmc.org/articles/PMC7296224
Autor:
Vanessa T. Garrido, Sulagna Banerjee
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims E-cadherin (Cdh1) is a key molecule for adherence required for maintenance of structural homeostasis. Loss of E-cadherin leads to poor prognosis and the development of resistance to chemotherapy in pancreatic cancer. Here, we evalua
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4e4aeeff55f00c8e44e1d524a68574c
https://doi.org/10.1016/j.jcmgh.2019.10.004
https://doi.org/10.1016/j.jcmgh.2019.10.004
Autor:
Anna L. Means
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims Identification and validation of new functionally relevant and pharmacologically actionable targets for pancreatic ductal adenocarcinoma (PDAC) remains a great challenge. Premalignant acinar cell reprogramming (acinar-to-ductal meta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a74de94d1c1ea932bbea8b4fa1374c44
http://europepmc.org/articles/PMC6889775
http://europepmc.org/articles/PMC6889775
Publikováno v:
Biochemical Journal
Stem cells are undifferentiated cells that can self-renew and generate specialized (functional) cell types. The remarkable ability of stem cells to differentiate towards functional cells makes them suitable modalities in cellular therapy (which means
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35c206efd777635d9376f9ffa9f769ea
https://doi.org/10.1042/bj20070167
https://doi.org/10.1042/bj20070167
Publikováno v:
Cell Biology International Reports
EMT (epithelial–mesenchymal transition) is a key process in the development of liver fibrosis. This process is also essential for liver morphogenesis in embryonic development. To study the cellular and molecular basis of EMT, we established two phe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2ecf7cb13e999f83a1c7d647e42e663
http://europepmc.org/articles/PMC3475435
http://europepmc.org/articles/PMC3475435
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