Zobrazeno 1 - 10 of 59 pro vyhledávání: '"CJD (Creutzfeldt-Jakob disease)"'
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Akademický článek
Understanding Intra-Species and Inter-Species Prion Conversion and Zoonotic Potential Using Protein Misfolding Cyclic Amplification
Autor: Alexander H. Peden, Suzanne Suleiman, Marcelo A. Barria
Publikováno v: Frontiers in Aging Neuroscience, Vol 13 (2021)
Prion diseases are fatal neurodegenerative disorders that affect humans and animals, and can also be transmitted from animals to humans. A fundamental event in prion disease pathogenesis is the conversion of normal host prion protein (PrPC) to a dise
Externí odkaz: https://doaj.org/article/60f9455d840646e99e671e8b05351369
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The integrity of chemically treated plasmid DNA as a chemical-based choice for prion clearance
Autor: Akifumi Matsuyama, Yasuharu Niwa, Hanayuki Okura, Tomoaki Teshigawara, Nozomi Takada, Kazue Isogai
Publikováno v: Regenerative Therapy
Regenerative Therapy, Vol 15, Iss, Pp 112-120 (2020)
In regenerative medical products for clinical applications, a major concern is the risk of ruminant-derived materials developing transmissible spongiform encephalopathy (TSE) in the manufacturing process. Because of the risk of TSE causing prion dise
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36aa35b8521a0cf7ee5f1f6315b87951
https://doi.org/10.1016/j.reth.2020.05.005
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A new model for sensitive detection of zoonotic prions by PrP transgenic Drosophila
Autor: Raymond Bujdoso, John Spiropoulos, Olivier Andreoletti, Alana M. Thackray
Publikováno v: The Journal of Biological Chemistry
Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2021, 297 (2), pp.100878. ⟨10.1016/j.jbc.2021.100878⟩
International audience; Prions are transmissible protein pathogens most reliably detected by a bioassay in a suitable host, typically mice. However, the mouse bioassay is slow and cumbersome, and relatively insensitive to low titers of prion infectiv
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d07e7894706e3ed17baa099100710dce
https://www.repository.cam.ac.uk/handle/1810/323904
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Detection and characterization of proteinase K-sensitive disease-related prion protein with thermolysin
Autor: Sabrina Cronier, Anthony R. Clarke, John Collinge, Graham S. Jackson, Jonathan D. F. Wadsworth, M. Howard Tattum, Nathalie Gros
Publikováno v: UK Funders’ TSE Workshop
UK Funders’ TSE Workshop, Labo/service de l'auteur, Ville service., Oct 1999, Warwick, United Kingdom. pp.Inconnu
Biochemical Journal
Disease-related PrP(Sc) [pathogenic PrP (prion protein)] is classically distinguished from its normal cellular precursor, PrP(C)(cellular PrP) by its detergent insolubility and partial resistance to proteolysis. Although molecular diagnosis of prion
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4111cf3755a12dc833b8d1db20cb7ed5
https://hal.inrae.fr/hal-02812714
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5
Review of diffuse cortical injury on diffusion-weighted imaging in acutely encephalopathic patients with an acronym: 'CRUMPLED'
Autor: John C. Benson, Alexander M. McKinney, Mehmet Gencturk, Haitao Huang, Yasemin Koksel
Publikováno v: European Journal of Radiology Open
European Journal of Radiology Open, Vol 5, Iss, Pp 194-201 (2018)
Highlights • Reduced diffusion is an early and important imaging to evaluate patients with acute encephalopathic syndromes. • The presence of diffuse cortical injury (DCI) on diffusion-weighted imaging (DWI) can help narrow the differential diagn
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53f85468d170c476f68e20e11d172897
https://doi.org/10.1016/j.ejro.2018.10.004
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Modulation of proteostasis by transcription factor NRF2 and impact in neurodegenerative diseases
Autor: Antonio Cuadrado, Marta Pajares, Ana I. Rojo
Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname
Redox Biology, Vol 11, Iss, Pp 543-553 (2017)
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Redox Biology
Neurodegenerative diseases are linked to the accumulation of specific protein aggregates, suggesting an intimate connection between injured brain and loss of proteostasis. Proteostasis refers to all the processes by which cells control the abundance
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f92176ef6df1b38f56b20a10b5b1ad8
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Exploratory study on the spatial relationship between emerging infectious diseases and urban characteristics: Cases from Korea
Autor: Dong-Hyun Kim
Publikováno v: Sustainable Cities and Society
Highlights • Spatial correlations of emerging infectious diseases were examined. • Urban characteristics factors differently affected each EID group. • Socio-economic status, environment, and government response are important factors. • Facto
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::154a53e3e1ac142976cea9dee1c63f9c
http://europepmc.org/articles/PMC7828747
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Unsung hero: Donald Darrow Matson’s legacy in pediatric neurosurgery
Autor: Alan R. Cohen, Roberta Rehder, Subash Lohani
Publikováno v: Journal of Neurosurgery: Pediatrics. 16:483-494
Donald Darrow Matson made seminal contributions to the field of pediatric neurosurgery. Born in 1913 in Fort Hamilton, New York, Matson was the youngest of four sons of an army colonel. He graduated from Cornell University and, years later, from Harv
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bb2a5e253302a3669e7e75e9d6c8a21
https://doi.org/10.3171/2015.4.peds156
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