Construction of an immunotoxin, D2C7-(scdsFv)-PE38KDEL, targeting EGFRwt and EGFRvIII for brain tumor therapy.

Autor: Chandramohan V; Preston Robert Tisch Brain Tumor Center at Duke and Department of Pathology, Duke University Medical Center, Durham, North Carolina 27710, USA., Bao X, Keir ST, Pegram CN, Szafranski SE, Piao H, Wikstrand CJ, McLendon RE, Kuan CT, Pastan IH, Bigner DD

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2013 Sep 01; Vol. 19 (17), pp. 4717-27. Date of Electronic Publication: 2013 Jul 15.

MRP3: a molecular target for human glioblastoma multiforme immunotherapy.

Autor: Kuan CT; Department of Pathology, Duke University Medical Center, Durham, North Carolina 27710, USA. kuan@duke.edu, Wakiya K, Herndon JE 2nd, Lipp ES, Pegram CN, Riggins GJ, Rasheed A, Szafranski SE, McLendon RE, Wikstrand CJ, Bigner DD

Publikováno v: BMC cancer [BMC Cancer] 2010 Sep 01; Vol. 10, pp. 468. Date of Electronic Publication: 2010 Sep 01.

Convection enhanced delivery of boronated EGF as a molecular targeting agent for neutron capture therapy of brain tumors.

Autor: Yang W; Department of Pathology, The Ohio State University, 165 Hamilton Hall, 1645 Neil Avenue, Columbus, OH, 43210, USA., Barth RF; Department of Pathology, The Ohio State University, 165 Hamilton Hall, 1645 Neil Avenue, Columbus, OH, 43210, USA. rolf.barth@osumc.edu., Wu G; Department of Pathology, The Ohio State University, 165 Hamilton Hall, 1645 Neil Avenue, Columbus, OH, 43210, USA., Huo T; Department of Pathology, The Ohio State University, 165 Hamilton Hall, 1645 Neil Avenue, Columbus, OH, 43210, USA., Tjarks W; Colleges of Pharmacy, The Ohio State University, Columbus, OH, USA., Ciesielski M; Department of Neurosurgery, Roswell Park Memorial Institute, Buffalo, NY, USA., Fenstermaker RA; Department of Neurosurgery, Roswell Park Memorial Institute, Buffalo, NY, USA., Ross BD; Department of Radiology, University of Michigan, Ann Arbor, MI, USA., Wikstrand CJ; Department of Microbiology, Saba University School of Medicine, Saba, Netherlands Antilles.; Department of Pathology, Duke University, Durham, NC, USA., Riley KJ; The Nuclear Reactor Laboratory, Massachusetts Institute of Technology, Cambridge, MA, USA.; Radiation Monitoring Devices, Inc, Watertown, MA, 02172, USA., Binns PJ; The Nuclear Reactor Laboratory, Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Radiology, Mount Auburn Hospital, Cambridge, MA, USA.

Publikováno v: Journal of neuro-oncology [J Neurooncol] 2009 Dec; Vol. 95 (3), pp. 355-365. Date of Electronic Publication: 2009 Jul 09.

Mutant epidermal growth factor receptor (EGFRvIII) contributes to head and neck cancer growth and resistance to EGFR targeting.

Autor: Sok JC; Department of Otolaryngology, and University of Pittsburgh Cancer Institute Biostatistics, University of Pittsburgh, Pennsylvania 15213, USA., Coppelli FM, Thomas SM, Lango MN, Xi S, Hunt JL, Freilino ML, Graner MW, Wikstrand CJ, Bigner DD, Gooding WE, Furnari FB, Grandis JR

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2006 Sep 01; Vol. 12 (17), pp. 5064-73.

Glycoprotein nonmetastatic melanoma protein B, a potential molecular therapeutic target in patients with glioblastoma multiforme.

Autor: Kuan CT; Preston Robert Tisch Brain Tumor Center at Duke, Department of Pathology, Duke University Medical Center, Durham, North Carolina, USA., Wakiya K, Dowell JM, Herndon JE 2nd, Reardon DA, Graner MW, Riggins GJ, Wikstrand CJ, Bigner DD

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2006 Apr 01; Vol. 12 (7 Pt 1), pp. 1970-82.