S81 Chronic diseases and TB risk factors among TB household contacts in Southern Africa

Autor: CJ Calderwood, E Marambire, D Banze, C Nhamuave, A Mfinanga, LT Minja, C Khosa, J Mutsvanga, N Heinrich, K Kranzer

Publikováno v: ‘Die Hard I’ – Resistance, screening and best management in TB.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::21da770961c37f77da3761cd35e01cbb
https://doi.org/10.1136/thorax-2022-btsabstracts.87

HIV, malnutrition, and noncommunicable disease epidemics among tuberculosis-affected households in east and southern Africa: A cross-sectional analysis of the ERASE-TB cohort.

Autor: Calderwood CJ; Clinical Research Department, London School of Hygiene & Tropical Medicine, London, United Kingdom.; The Health Research Unit Zimbabwe, Biomedical Research and Training Institute, Harare, Zimbabwe., Marambire ET; The Health Research Unit Zimbabwe, Biomedical Research and Training Institute, Harare, Zimbabwe.; CIHLMU Center for International Health, University Hospital, LMU Munich, Munich, Germany., Larsson L; The Health Research Unit Zimbabwe, Biomedical Research and Training Institute, Harare, Zimbabwe.; Division of Infectious Diseases and Tropical Medicine, University Hospital, LMU Munich, Munich, Germany., Banze D; CIHLMU Center for International Health, University Hospital, LMU Munich, Munich, Germany.; Instituto Nacional de Saúde (INS), Marracuene, Mozambique., Mfinanga A; CIHLMU Center for International Health, University Hospital, LMU Munich, Munich, Germany.; National Institute for Medical Research-Mbeya Medical Research Centre, Mbeya, Tanzania., Nhamuave C; Instituto Nacional de Saúde (INS), Marracuene, Mozambique., Appalarowthu T; Division of Infectious Diseases and Tropical Medicine, University Hospital, LMU Munich, Munich, Germany., Mugava M; The Health Research Unit Zimbabwe, Biomedical Research and Training Institute, Harare, Zimbabwe., Ribeiro J; Instituto Nacional de Saúde (INS), Marracuene, Mozambique., Towo PE; National Institute for Medical Research-Mbeya Medical Research Centre, Mbeya, Tanzania., Madziva K; The Health Research Unit Zimbabwe, Biomedical Research and Training Institute, Harare, Zimbabwe., Dixon J; Department of Global Health and Development, London School of Hygiene & Tropical Medicine, London, United Kingdom., Held K; Division of Infectious Diseases and Tropical Medicine, University Hospital, LMU Munich, Munich, Germany.; German Centre for Infection Research (DZIF), partner site Munich, Germany.; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Immunology, Infection and Pandemic Research, Munich, Germany., Minja LT; National Institute for Medical Research-Mbeya Medical Research Centre, Mbeya, Tanzania., Mutsvangwa J; Biomedical Research and Training Institute, Harare, Zimbabwe., Khosa C; Instituto Nacional de Saúde (INS), Marracuene, Mozambique., Heinrich N; Division of Infectious Diseases and Tropical Medicine, University Hospital, LMU Munich, Munich, Germany.; German Centre for Infection Research (DZIF), partner site Munich, Germany.; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Immunology, Infection and Pandemic Research, Munich, Germany., Fielding K; TB Centre, London School of Hygiene & Tropical Medicine, London, United Kingdom., Kranzer K; Clinical Research Department, London School of Hygiene & Tropical Medicine, London, United Kingdom.; The Health Research Unit Zimbabwe, Biomedical Research and Training Institute, Harare, Zimbabwe.; Division of Infectious Diseases and Tropical Medicine, University Hospital, LMU Munich, Munich, Germany.; German Centre for Infection Research (DZIF), partner site Munich, Germany.

Publikováno v: PLoS medicine [PLoS Med] 2024 Sep 16; Vol. 21 (9), pp. e1004452. Date of Electronic Publication: 2024 Sep 16 (Print Publication: 2024).

Resolution of tuberculosis blood RNA signatures fails to discriminate persistent sputum culture positivity after eight weeks of anti-tuberculous treatment.

Autor: Calderwood CJ; Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK.; Contributed equally., Sanchez Martinez A; Division of Infection and Immunity, University College London, London, UK.; Contributed equally., Greenan-Barrett J; Department of Respiratory Medicine, University College London Hospitals NHS Foundation Trust, London, UK., Turner CT; Division of Infection and Immunity, University College London, London, UK., Oguti B; Division of Infection and Immunity, University College London, London, UK., Roe JK; Division of Infection and Immunity, University College London, London, UK., Gupta R; Institute of Health Informatics, University College London, London, UK., Martineau AR; Blizard Institute, Queen Mary University of London, London, UK.; Co-senior authors., Noursadeghi M; Division of Infection and Immunity, University College London, London, UK m.noursadeghi@ucl.ac.uk a.martineau@qmul.ac.uk.; Co-senior authors.

Publikováno v: The European respiratory journal [Eur Respir J] 2024 Aug 01. Date of Electronic Publication: 2024 Aug 01.

Blood RNA signatures outperform CRP triage of tuberculosis lymphadenitis and pericarditis.

Autor: Mann T, Minnies S, Gupta RK, Reeve BW, Nyawo G, Palmer Z, Naidoo C, Doubell A, Pecararo A, John TJ, Schubert P, Calderwood CJ, Chandran A, Theron G, Noursadeghi M

Publikováno v: MedRxiv : the preprint server for health sciences [medRxiv] 2024 Jul 03. Date of Electronic Publication: 2024 Jul 03.

Blood RNA biomarkers for tuberculosis screening in people living with HIV before antiretroviral therapy initiation: a diagnostic accuracy study.

Autor: Mann T; Division of Infection and Immunity, University College London, London, UK., Gupta RK; Institute of Health Informatics, University College London, London, UK., Reeve BWP; DSI-NRF Centre of Excellence for Biomedical Tuberculosis Research, South African Medical Research Council Centre for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa., Ndlangalavu G; DSI-NRF Centre of Excellence for Biomedical Tuberculosis Research, South African Medical Research Council Centre for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa., Chandran A; Division of Infection and Immunity, University College London, London, UK., Krishna AP; Division of Infection and Immunity, University College London, London, UK., Calderwood CJ; Department of Clinical Research, Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, UK., Tshivhula H; DSI-NRF Centre of Excellence for Biomedical Tuberculosis Research, South African Medical Research Council Centre for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa., Palmer Z; DSI-NRF Centre of Excellence for Biomedical Tuberculosis Research, South African Medical Research Council Centre for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa., Naidoo S; DSI-NRF Centre of Excellence for Biomedical Tuberculosis Research, South African Medical Research Council Centre for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa., Mbu DL; DSI-NRF Centre of Excellence for Biomedical Tuberculosis Research, South African Medical Research Council Centre for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa., Theron G; DSI-NRF Centre of Excellence for Biomedical Tuberculosis Research, South African Medical Research Council Centre for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa., Noursadeghi M; Division of Infection and Immunity, University College London, London, UK. Electronic address: m.noursadeghi@ucl.ac.uk.

Publikováno v: The Lancet. Global health [Lancet Glob Health] 2024 May; Vol. 12 (5), pp. e783-e792. Date of Electronic Publication: 2024 Apr 04.