Zobrazeno 1 - 10
of 1 955
pro vyhledávání: '"CIRCULATING DNA"'
Autor:
Alexia Mirandola, Andrei Kudriavtsev, Catalina Isabel Cofre Muñoz, Raquel Comas Navarro, Marco Macagno, Saidi Daoud, Cynthia Sanchez, Brice Pastor, Ekaterina Pisareva, Mireia Sanchis Marin, Javier Gonzalo Ruiz, Alejandro Piris, Ariadna Garcia Rodriguez, Nadia Saoudi Gonzalez, Ana Vivancos, Virginia Quarà, Alfredo Mellano, Felice Borghi, Giorgio Corti, Caterina Marchiò, Anna Sapino, Alice Bartolini, Giovanni Crisafulli, Alberto Bardelli, Massimo Di Maio, Gerald Lossaint, Florence Frayssinoux, Evelyne Crapez, Marc Ychou, Ramon Salazar Soler, Elisabetta Fenocchio, Paula X. Fernandez Calotti, Thibault Mazard, Cristina Santos Vivas, Elena Elez, Federica Di Nicolantonio, Alain R. Thierry
Publikováno v:
EBioMedicine, Vol 108, Iss , Pp 105352- (2024)
Summary: Background: We studied the poorly-known dynamics of circulating DNA (cir-nDNA), as monitored prospectively over an extended post-surgery period, in patients with cancer. Methods: On patients with stage III colon cancer (N = 120), using perso
Externí odkaz:
https://doaj.org/article/00bd9725b0694cf5a6a8cd91ec3b094f
Autor:
Ludivine Beaussire-Trouvay, Orianne Duhamel, Anne Perdrix, Emilie Lévêque, Roman Vion, Anne Rovelet-Lecrux, Nasrin Sarafan-Vasseur, Frédéric Di Fiore, Agathe Crouzet, Marianne Leheurteur, Florian Clatot
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundCervical cancers are mainly caused by an oncogenic HPV. For locally advanced stages, the standard treatment is radio-chemotherapy (RTCT) followed by brachytherapy. Nevertheless, the prognosis remains highly heterogeneous between patients.Ob
Externí odkaz:
https://doaj.org/article/d35a4a82fcae4764b1becf6a438cc466
Autor:
Anna Citarella, Zein Mersini Besharat, Sofia Trocchianesi, Tanja Milena Autilio, Antonella Verrienti, Giuseppina Catanzaro, Elena Splendiani, Zaira Spinello, Silvia Cantara, Patrizia Zavattari, Eleonora Loi, Cristina Romei, Raffaele Ciampi, Luciano Pezzullo, Maria Grazia Castagna, Antonio Angeloni, Rosella Elisei, Cosimo Durante, Agnese Po, Elisabetta Ferretti
Publikováno v:
Biomarker Research, Vol 11, Iss 1, Pp 1-5 (2023)
Abstract Medullary Thyroid Carcinoma (MTC) is a rare neuroendocrine tumour whose diagnosis includes evaluating calcitonin serum levels, which can present fluctuations unrelated to MTC. Here, we investigated circulating DNA fragmentation and methylati
Externí odkaz:
https://doaj.org/article/5d194c6b6274431c8479e3b83625ff68
Autor:
Julieta E. Rodriguez, Damien Vasseur, Mohamed Amine Bani, Odile Cabaret, Sophie Cotteret, Martine Muleris, Veronica Golbarg, David Malka, Thomas Pudlarz, Olivier Caron, Cristina Smolenschi
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
IntroductionMicrosatellite instability (MSI) is a genetic marker that is useful in the detection and treatment of Lynch syndrome (Sd). Although conventional techniques such as immunohistochemistry (IHC) and polymerase chain reaction (PCR) are the sta
Externí odkaz:
https://doaj.org/article/54fec50bb2b942a79241dc0f02c735e2
Autor:
Valérie M. Schwitzgebel, Jean-Louis Blouin, Barbara Dehos, Bettina Köhler-Ballan, Jardena J. Puder, Claudine Rieubland, Maria Triantafyllidou, Anne Zanchi, Marc Abramowicz, Thierry Nouspikel
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
BackgroundMutations in the GCK gene cause Maturity Onset Diabetes of the Young (GCK-MODY) by impairing glucose-sensing in pancreatic beta cells. During pregnancy, managing this type of diabetes varies based on fetal genotype. Fetuses carrying a GCK m
Externí odkaz:
https://doaj.org/article/e4add68890ec4c8bb0e802631da0d9d9
Autor:
Shai Rosenberg, Gil Ben Cohen, Shumei Kato, Ryosuke Okamura, Scott M. Lippman, Razelle Kurzrock
Publikováno v:
Molecular Oncology, Vol 17, Iss 9, Pp 1844-1856 (2023)
Genomic analysis, performed on tumoral tissue DNA and on circulating tumor DNA (ctDNA) from blood, is the cornerstone of precision cancer medicine. Herein, we characterized the clinical prognostic implications of the concordance of alterations in maj
Externí odkaz:
https://doaj.org/article/d082f4cb7f7c40e2bbf553988eea8236
Autor:
Angeline Ginzac, Marie-Céleste Ferreira, Anne Cayre, Clément Bouvet, Julian Biau, Ioana Molnar, Nicolas Saroul, Nathalie Pham-Dang, Xavier Durando, Maureen Bernadach
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-7 (2023)
Abstract Background Sensitive and reproducible detection of residual disease after treatment is a major challenge for patients with locally advanced head and neck cancer. Indeed, the current imaging techniques are not always reliable enough to determ
Externí odkaz:
https://doaj.org/article/f7eeed07e8554ecf923644de1f90a6d1
Autor:
Jean-Paul Cristol, Alain R. Thierry, Anne-Sophie Bargnoux, Marion Morena-Carrere, Bernard Canaud
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
Externí odkaz:
https://doaj.org/article/7b1a4f1b4ff24f0980deca69bd1aa9ae
Publikováno v:
Genes and Diseases, Vol 10, Iss 3, Pp 948-959 (2023)
Pathological cardiac damage during heart failure is associated with cell death and damage associated molecular patterns (DAMPs) release which triggers a viscous cycle of sterile inflammation to mediate maladaptive cardiac tissue remodelling during th
Externí odkaz:
https://doaj.org/article/7db1482d3a184e12a218f2bc3adcc834
Autor:
Jean-Paul Cristol, Alain R. Thierry, Anne-Sophie Bargnoux, Marion Morena-Carrere, Bernard Canaud
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
Despite significant progress in dialysis modalities, intermittent renal replacement therapy remains an “unphysiological” treatment that imperfectly corrects uremic disorders and may lead to low-grade chronic inflammation, neutrophil activation, a
Externí odkaz:
https://doaj.org/article/2bc22d3f851c4b73a4c59dae35c9c76a