Impact of aerobic exercise type on blood flow, muscle energy metabolism, and mitochondrial biogenesis in experimental lower extremity artery disease

Autor: Karima Bouzourene, Lucia Mazzolai, Christelle Bielmann, Nathalie Rosenblatt-Velin, Rolf Gruetter, Jean-François Aubert, Maxime Pellegrin, Carole Poitry-Yamate

Publikováno v: Scientific reports, vol. 10, no. 1, pp. 14048
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)

Exercise training (ET) is recommended for lower extremity artery disease (LEAD) management. However, there is still little information on the hemodynamic and metabolic adaptations by skeletal muscle with ET. We examined whether hindlimb perfusion/vas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1906a0b43f44fe05c16a762798fe1cc1
https://serval.unil.ch/notice/serval:BIB_4E558217EFB1

Experimental peripheral arterial disease: new insights into muscle glucose uptake, macrophage, and T-cell polarization during early and late stages

Autor: Carole Poitry-Yamate, Maxime Pellegrin, Vladimir Mlynarik, Lucia Mazzolai, François Feihl, Jean-François Aubert, Rolf Gruetter, Karima Bouzourene

Publikováno v: Physiological Reports, Vol. 2, No 2 (2014) P. e00234
Physiological Reports
Physiological Reports, vol. 2, no. 2, pp. e00234

Peripheral arterial disease (PAD) is a common disease with increasing prevalence, presenting with impaired walking ability affecting patient's quality of life. PAD epidemiology is known, however, mechanisms underlying functional muscle impairment rem

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eff2a54e78b6c988a0e1f6ba527beae7
https://archive-ouverte.unige.ch/unige:44991

Feasibility of direct mapping of cerebral fluorodeoxy-D-glucose metabolism in situ at subcellular resolution using soft X-ray fluorescence

Autor: Poitry-Yamate, Carole, Gianoncelli, Alessandra, Kaulich, Burkhard, Kourousias, George, Magill, Arthur W., Lepore, Mario, Gajdosik, Vincent, Gruetter, Rolf

Publikováno v: Journal of Neuroscience Research, Vol. 91, No 8 (2013) pp. 1050-1058
Journal of neuroscience research

Glucose metabolism is difficult to image with cellular resolution in mammalian brain tissue, particularly with (18) fluorodeoxy-D-glucose (FDG) positron emission tomography (PET). To this end, we explored the potential of synchrotron-based low-energy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::3ee15488f390fc3160fad3da132bfc6f
https://archive-ouverte.unige.ch/unige:33034

9.4–14.1T small-animal PET-MR imaging: Feasibility analysis of LYSO APD readout via long signal lines

Autor: Joao Varela, Catarina Ortigao, R. Bugalho, Rolf Gruetter, Arthur W. Magill, J.A. Neves, Rui Silva, José C. Da Silva

Publikováno v: Nuclear Instruments and Methods in Physics Research. A, Vol. 702 (2013) pp. 98-100

In the present work we intend to assess the readout feasibility of Avalanche Photodiode (APD) detectors via long signal lines for the development of a combined small-animal PET-MR prototype based on the ClearPEM technology. The detection performance

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56d8799b116db1039ee7e80294571da5
https://archive-ouverte.unige.ch/unige:33036

Hepatic glucose sensing is required to preserve β cell glucose competence

Autor: Seyer Pascal, Vallois David, Poitry-Yamate Carole, Schütz Frédéric, Metref Salima, Tarussio David, Maechler Pierre, Staels Bart, Lanz Bernard, Grueter Rolf, Decaris Julie, Turner Scott, Da Costa Anabela, Preitner Frédéric, Minehira Kaori, Foretz Marc, Thorens Bernard

Publikováno v: Journal of Clinical Investigation, Vol. 123, No 4 (2013) pp. 1662-76
Journal of Clinical Investigation, vol. 123, no. 4, pp. 1662-1676
Journal of Clinical Investigation

Liver glucose metabolism plays a central role in glucose homeostasis and may also regulate feeding and energy expenditure. Here we assessed the impact of glucose transporter 2 (Glut2) gene inactivation in adult mouse liver (LG2KO mice). Loss of Glut2

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15358b3f631566e869bb768f4696dfe8
https://archive-ouverte.unige.ch/unige:28233