Zobrazeno 1 - 10
of 99
pro vyhledávání: '"CIARA M SHAVER"'
Autor:
Jamie E Meegan, Ciara M Shaver, Nathan D Putz, Jordan J Jesse, Stuart R Landstreet, Han Noo Ri Lee, Tatiana N Sidorova, J Brennan McNeil, James L Wynn, Joyce Cheung-Flynn, Padmini Komalavilas, Colleen M Brophy, Lorraine B Ware, Julie A Bastarache
Publikováno v:
PLoS ONE, Vol 15, Iss 2, p e0228727 (2020)
Increased endothelial permeability is central to the pathogenesis of sepsis and leads to organ dysfunction and death but the endogenous mechanisms that drive increased endothelial permeability are not completely understood. We previously reported tha
Externí odkaz:
https://doaj.org/article/e068d1cb04d84396b01306e30f41f480
Autor:
Kaitlyn C. Chapin, Alexander G. Dragnich, Whitney D. Gannon, Abigail K. Martel, Matthew Bacchetta, David B. Erasmus, Ciara M. Shaver, Anil J. Trindade
Publikováno v:
JHLT Open, Vol 4, Iss , Pp 100046- (2024)
Background: Prolonged intubation following lung transplantation is thought to delay recovery, yet a paucity of data exists regarding risk factors and outcomes related to extubation failure. Methods: We performed a single-center, retrospective analysi
Externí odkaz:
https://doaj.org/article/06631d60118943b2b23f98a61a90e469
Autor:
Ciara M. Shaver, Jinyuan Liu, Ke Xu, Gong Yang, Madeline C. Morrison, Alexis Goree, Heather O’Dell, Roman Perri, Matthew Bacchetta, Loren Lipworth, Anil J. Trindade
Publikováno v:
JHLT Open, Vol 3, Iss , Pp 100029- (2024)
Transplantation of lungs from donors with active hepatitis C viremia with early initiation of antiviral therapy has been shown to have similar short- and medium-term outcomes compared to transplantation of lungs from nonviremic donors. Consideration
Externí odkaz:
https://doaj.org/article/c7285fd52c284fd0813523d18391f7b2
Autor:
Anil J. Trindade, MD, Kaitlyn C. Chapin, AGNP-C, CCTC, Jennifer N. Gray, PharmD, Yuka Furuya, MD, MSCI, Amy Mullican, RN, Haley Hoy, ACNP, PhD, Caitlin T. Demarest, MD, PhD, Ivan M. Robbins, MD, Matthew Bacchetta, MD, MBA, David B. Erasmus, MD, Ciara M. Shaver, MD, PhD
Publikováno v:
Transplantation Direct, Vol 9, Iss 6, p e1487 (2023)
Background. Donor-derived cell-free DNA (dd-cfDNA%) is a biomarker of early acute lung allograft dysfunction (ALAD), with a value of ≥1.0% indicating injury. Whether dd-cfDNA% is a useful biomarker in patients >2 y posttransplant is unknown. Our gr
Externí odkaz:
https://doaj.org/article/711fae669f77454abf6c75532b107e48
Autor:
Anil J. Trindade, MD, Kaitlyn C. Chapin, AGNP, Amy Mullican, RN, Jennifer N. Gray, PharmD, Haley Hoy, AGNP, PhD, Caitlin T. Demarest, MD, PhD, Eric S. Lambright, MD, Katie A. McPherson, MD, Stephanie G. Norfolk, MD, Ivan M. Robbins, MD, Matthew Bacchetta, MD, MBA, David B. Erasmus, MD, Ciara M. Shaver, MD, PhD
Publikováno v:
Transplantation Direct, Vol 8, Iss 12, p e1411 (2022)
Background. Donor-derived cell-free DNA (dd-cfDNA) is a useful biomarker for the diagnosis of acute allograft injury within the first 1 to 2 y after lung transplant, but its utility for diagnosing chronic lung allograft dysfunction (CLAD) has not yet
Externí odkaz:
https://doaj.org/article/f0292f4e8b434720bba0eed3fe2670f5
Autor:
Anil J. Trindade, MD, Whitney D. Gannon, MS, MSN, John W. Stokes, MD, Eric S. Lambright, MD, Katie A. McPherson, MD, Stephanie G. Norfolk, MD, Ivan M. Robbins, MD, Ciara M. Shaver, MD, PhD, Matthew Bacchetta, MD, MBA
Publikováno v:
Transplantation Direct, Vol 8, Iss 10, p e1371 (2022)
Externí odkaz:
https://doaj.org/article/b8473b33ef7d4668b64675b21b711cc8
Autor:
Jamie E. Meegan, Padmini Komalavilas, Joyce Cheung‐Flynn, Tsz Wing Yim, Nathan D. Putz, Jordan J. Jesse, Kyle D. Smith, Tatiana N. Sidorova, Han Noo Ri Lee, Toria Tomasek, Ciara M. Shaver, Lorraine B. Ware, Colleen M. Brophy, Julie A. Bastarache
Publikováno v:
Physiological Reports, Vol 10, Iss 11, Pp n/a-n/a (2022)
Abstract Sepsis is a devastating disease with high morbidity and mortality and no specific treatments. The pathophysiology of sepsis involves a hyperinflammatory response and release of damage‐associated molecular patterns (DAMPs), including adenos
Externí odkaz:
https://doaj.org/article/c442a96d140a4867a2a4fce0591bff3d
Autor:
Magdalene K. Ameka, William N. Beavers, Ciara M. Shaver, Lorraine B. Ware, Vern Eric Kerchberger, Kelly Q. Schoenfelt, Lili Sun, Tatsuki Koyama, Eric P. Skaar, Lev Becker, Alyssa H. Hasty
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 13, p 7417 (2022)
Adipocyte iron overload is a maladaptation associated with obesity and insulin resistance. The objective of the current study was to determine whether and how adipose tissue macrophages (ATMs) regulate adipocyte iron concentrations and whether this i
Externí odkaz:
https://doaj.org/article/cf5795b7a636402bbc78af73b675760b
Autor:
Wen-Kuang Yu, J. Brennan McNeil, Nancy E. Wickersham, Ciara M. Shaver, Julie A. Bastarache, Lorraine B. Ware
Publikováno v:
Critical Care, Vol 23, Iss 1, Pp 1-9 (2019)
Abstract Background Vascular endothelial cadherin (VE-cadherin) is a membrane protein that is the major component of adherens junctions between endothelial cells. It is crucial for regulating vascular integrity, endothelial permeability, and angiogen
Externí odkaz:
https://doaj.org/article/3a19087c659c49a39cfa52932fb0c1c0
Autor:
Ciara M. Shaver, Stuart R. Landstreet, Sangamithra Pugazenthi, Fiona Scott, Nathan Putz, Lorraine B. Ware, Julie A. Bastarache
Publikováno v:
Physiological Reports, Vol 8, Iss 21, Pp n/a-n/a (2020)
Abstract Cell‐free hemoglobin (CFH) is associated with severe lung injury in human patients and is sufficient to induce airspace inflammation and alveolar–capillary barrier dysfunction in an experimental model of acute lung injury. The mechanisms
Externí odkaz:
https://doaj.org/article/38bde6fc94dd4153850cee25b801e450