Zobrazeno 1 - 10
of 387
pro vyhledávání: '"CHRISTOPHER J. MURPHY"'
Autor:
Sangwan Park, M. Isabel Casanova, Danika L. Bannasch, Nicole L. Daley, Soohyun Kim, John Kuchtey, Filipe Espinheira Gomes, Brian C. Leonard, Kathryn L. Good, Bianca da C. Martins, Christopher J. Murphy, Sara M. Thomasy
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract Acute primary angle closure glaucoma is a potentially blinding ophthalmic emergency requiring prompt treatment to lower the elevated intraocular pressure in humans and dogs. The PACG in most of canine breeds is epidemiologically similar to h
Externí odkaz:
https://doaj.org/article/f050ae50c7b7467fbed621402c5b9467
Autor:
Sangwan Park, Lionel Sebbag, Bret A. Moore, M. Isabel Casanova, Brian C. Leonard, Nicole L. Daley, Kirsten A. Steele, Jennifer Y. Li, Christopher J. Murphy, Sara M. Thomasy
Publikováno v:
BMC Veterinary Research, Vol 18, Iss 1, Pp 1-7 (2022)
Abstract Background Imaging features obtained with Fourier-domain optical coherence tomography (FD-OCT) and in vivo confocal microscopy (IVCM) for corneal stromal disorders have been sparsely reported in dogs. This case report is a compilation of ima
Externí odkaz:
https://doaj.org/article/fb17b4e768e54d3cb7d7989c62c9a97c
Autor:
Andy Shao, Antonio Jacobo Lopez, JiaJia Chen, Addy Tham, Seanne Javier, Alejandra Quiroz, Sonia Frick, Edward M. Levine, K. C. Kent Lloyd, Brian C. Leonard, Christopher J. Murphy, Thomas M. Glaser, Ala Moshiri
Publikováno v:
Disease Models & Mechanisms, Vol 15, Iss 7 (2022)
Retinitis pigmentosa (RP), a retinal degenerative disease, is the leading cause of heritable blindness. Previously, we described that Arap1−/− mice develop a similar pattern of photoreceptor degeneration. Arap1 is an Arf-directed GTPase-activatin
Externí odkaz:
https://doaj.org/article/1e0ef4641f5c422b9cd28293ca0d8764
Autor:
Allison H. Shannon, Sara A. Adelman, Erin A. Hisey, Sanskruti S. Potnis, Vanessa Rozo, Madeline W. Yung, Jennifer Y. Li, Christopher J. Murphy, Sara M. Thomasy, Brian C. Leonard
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Microbial keratitis is a common cause of ocular pain and visual impairment worldwide. The ocular surface has a relatively paucicellular microbial community, mostly found in the conjunctiva, while the cornea would be considered relatively sterile. How
Externí odkaz:
https://doaj.org/article/8789fda5743b43a08495ec708a850fee
Autor:
Soohyun Kim, Sara M. Thomasy, Vijay Krishna Raghunathan, Leandro B.C. Teixeira, Ala Moshiri, Paul FitzGerald, Christopher J. Murphy
Publikováno v:
Molecular Vision, Vol 25, Iss 1, Pp 129-142 (2019)
Purpose: To identify the effects of a single copy deletion of Yap1 (Yap1+/−) in the mouse eye, the ocular phenotypic consequences of Yap1+/− were determined in detail. Methods: Complete ophthalmic examinations, as well as corneal esthesiometry
Externí odkaz:
https://doaj.org/article/73faeb97487541e49b549242e9e69cb3
Autor:
Ulrike Meister, Christiane Görig, Christopher J. Murphy, Hubertus Haan, Bernhard Ohnesorge, Michael H. Boevé
Publikováno v:
BMC Veterinary Research, Vol 14, Iss 1, Pp 1-8 (2018)
Abstract Background Phacoemulsification and intraocular lens (IOL) implantation during cataract surgery in horses occur with increasing frequency. To reduce the postoperative refractive error it is necessary to determine the proper IOL power. In the
Externí odkaz:
https://doaj.org/article/0ce77d2646084df586595d3590638f64
Publikováno v:
BMC Biology, Vol 15, Iss 1, Pp 1-3 (2017)
Abstract The first report of multiple, blind, wild birds in good health suggests vision is not necessary for the survival of kiwi.
Externí odkaz:
https://doaj.org/article/68568c72c82c4f7686a5a2a03a5821be
Autor:
Bret A. Moore, Brian C. Leonard, Lionel Sebbag, Sydney G. Edwards, Ann Cooper, Denise M. Imai, Ewan Straiton, Luis Santos, Christopher Reilly, Stephen M. Griffey, Lynette Bower, David Clary, Jeremy Mason, Michel J. Roux, Hamid Meziane, Yann Herault, International Mouse Phenotyping Consortium, Colin McKerlie, Ann M. Flenniken, Lauryl M. J. Nutter, Zorana Berberovic, Celeste Owen, Susan Newbigging, Hibret Adissu, Mohammed Eskandarian, Chih-Wei Hsu, Sowmya Kalaga, Uchechukwu Udensi, Chinwe Asomugha, Ritu Bohat, Juan J. Gallegos, John R. Seavitt, Jason D. Heaney, Arthur L. Beaudet, Mary E. Dickinson, Monica J. Justice, Vivek Philip, Vivek Kumar, Karen L. Svenson, Robert E. Braun, Sara Wells, Heather Cater, Michelle Stewart, Sharon Clementson-Mobbs, Russell Joynson, Xiang Gao, Tomohiro Suzuki, Shigeharu Wakana, Damian Smedley, J. K. Seong, Glauco Tocchini-Valentini, Mark Moore, Colin Fletcher, Natasha Karp, Ramiro Ramirez-Solis, Jacqueline K. White, Martin Hrabe de Angelis, Wolfgang Wurst, Sara M. Thomasy, Paul Flicek, Helen Parkinson, Steve D. M. Brown, Terrence F. Meehan, Patsy M. Nishina, Stephen A. Murray, Mark P. Krebs, Ann-Marie Mallon, K. C. Kent Lloyd, Christopher J. Murphy, Ala Moshiri
Publikováno v:
Communications Biology, Vol 2, Iss 1, Pp 1-2 (2019)
In the original published version of the article, Valerie Vancollie was mistakenly omitted from the list of members of the International Mouse Phenotyping Consortium. In addition, recognition of funding from Wellcome Trust grant WT098051 was mistaken
Externí odkaz:
https://doaj.org/article/8d8550fc215047fe947e147fb5638498
Autor:
Brian C. Leonard, Krista Cosert, Moritz Winkler, Ariana Marangakis, Sara M. Thomasy, Christopher J. Murphy, James V. Jester, Vijay Krishna Raghunathan
Publikováno v:
Bioengineering, Vol 7, Iss 1, p 4 (2019)
The cornea is the most external layer of the eye and serves two important roles in (1) the refraction of light and (2) protection from the outside environment, both of which are highly dependent on the collagen assembly of the corneal stroma. This st
Externí odkaz:
https://doaj.org/article/025ddb90905c4a919f2ebdd161ffd8e1
Publikováno v:
Endoscopy International Open, Vol 04, Iss 03, Pp E292-E295 (2016)
Background and study aims: Pneumoperitoneum following PEG placement has been reported in up to 60 % of cases, and while usually benign and self-limited, it can lead to evaluation for suspected perforation. This study was designed to determine whether
Externí odkaz:
https://doaj.org/article/e9d12c9f23ad4e9fa566159ba103ce04