Zobrazeno 1 - 10
of 368
pro vyhledávání: '"CHRISTOPHER A. DAWSON"'
Autor:
Jason K. W. Yap, Khalil Uddin, Rachel Pounds, Danielle O’Neill, Sean Kehoe, Raji Ganesan, Christopher W. Dawson
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Abstract In a previous study, we showed that the Hedgehog (Hh) signalling pathway is aberrantly activated in vulval squamous cell carcinoma (VSCC). In this study, we further validated our findings on a prospective cohort of primary VSCC cases, where
Externí odkaz:
https://doaj.org/article/05f946613f6a40b3894bfa1218318429
Autor:
Jeff P. Bruce, Ka-Fai To, Vivian W. Y. Lui, Grace T. Y. Chung, Yuk-Yu Chan, Chi Man Tsang, Kevin Y. Yip, Brigette B. Y. Ma, John K. S. Woo, Edwin P. Hui, Michael K. F. Mak, Sau-Dan Lee, Chit Chow, Sharmila Velapasamy, Yvonne Y. Y. Or, Pui Kei Siu, Samah El Ghamrasni, Stephenie Prokopec, Man Wu, Johnny S. H. Kwan, Yuchen Liu, Jason Y. K. Chan, C. Andrew van Hasselt, Lawrence S. Young, Christopher W. Dawson, Ian C. Paterson, Lee-Fah Yap, Sai-Wah Tsao, Fei-Fei Liu, Anthony T. C. Chan, Trevor J. Pugh, Kwok-Wai Lo
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
The genomic characterisation of nasopharyngeal carcinoma (NPC) remains crucial. Here, the authors perform whole-genome sequencing for 70 NPCs with EBV gene expression, report the somatic alterations and EBV-mediated effects converging on NF-κB activ
Externí odkaz:
https://doaj.org/article/84b65b92c11446b886dec64811b68199
Autor:
Talya S. Levitz, Gisele A. Andree, Rohan Jonnalagadda, Christopher D. Dawson, Rebekah E. Bjork, Catherine L. Drennan
Publikováno v:
PLoS ONE, Vol 17, Iss 6 (2022)
Ribonucleotide reductases (RNRs) use radical-based chemistry to catalyze the conversion of all four ribonucleotides to deoxyribonucleotides. The ubiquitous nature of RNRs necessitates multiple RNR classes that differ from each other in terms of the p
Externí odkaz:
https://doaj.org/article/52003eb3d4d54b7ea8f8b02ebfa4a81f
Autor:
Jeff P. Bruce, Ka-Fai To, Vivian W. Y. Lui, Grace T. Y. Chung, Yuk-Yu Chan, Chi Man Tsang, Kevin Y. Yip, Brigette B. Y. Ma, John K. S. Woo, Edwin P. Hui, Michael K. F. Mak, Sau-Dan Lee, Chit Chow, Sharmila Velapasamy, Yvonne Y. Y. Or, Pui Kei Siu, Samah El Ghamrasni, Stephenie Prokopec, Man Wu, Johnny S. H. Kwan, Yuchen Liu, Jason Y. K. Chan, C. Andrew van Hasselt, Lawrence S. Young, Christopher W. Dawson, Ian C. Paterson, Lee-Fah Yap, Sai-Wah Tsao, Fei-Fei Liu, Anthony T. C. Chan, Trevor J. Pugh, Kwok-Wai Lo
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/f4c5624de0d740c496d631d66856f4cf
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Nasopharyngeal carcinoma (NPC) is closely associated with Epstein-Barr virus (EBV) infection. It is also characterized by heavy infiltration with non-malignant leucocytes. The EBV-encoded latent membrane protein 1 (LMP1) is believed to play an import
Externí odkaz:
https://doaj.org/article/4850ee0319144e15be9bba972cb65b41
Publikováno v:
Pathogens, Vol 10, Iss 8, p 982 (2021)
Latent membrane protein 1 (LMP1), the major oncoprotein encoded by Epstein–Barr virus (EBV), is expressed at widely variable levels in undifferentiated nasopharyngeal carcinoma (NPC) biopsies, fueling intense debate in the field as to the importanc
Externí odkaz:
https://doaj.org/article/54bcc61173264b23a1c6febb51fccc33
Publikováno v:
Pathogens, Vol 10, Iss 4, p 459 (2021)
Epigallocatechin-3-gallate (EGCG), the primary bioactive polyphenol in green tea, has been shown to inhibit the growth of human papilloma virus (HPV)-transformed keratinocytes. Here, we set out to examine the consequences of EGCG treatment on the gro
Externí odkaz:
https://doaj.org/article/df76d9deb341473095fb378fbf7ac741
Autor:
Robert Z. Orlowski, Donna M. Weber, Jatin J. Shah, Christopher W. Dawson, Veerabhadran Baladandayuthapani, Heather C. Lin, Shannon C. Kenney, Janet E. Mertz, Hans C. Lee, Xiaobin Wang, Tawin Iempridee, Richard J. Jones
Combination indices of LEN, THAL or POM in combination with GCV.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26d480dcc2b4e12caf5ed191298bfd11
https://doi.org/10.1158/1078-0432.22461624
https://doi.org/10.1158/1078-0432.22461624
Autor:
Robert Z. Orlowski, Donna M. Weber, Jatin J. Shah, Christopher W. Dawson, Veerabhadran Baladandayuthapani, Heather C. Lin, Shannon C. Kenney, Janet E. Mertz, Hans C. Lee, Xiaobin Wang, Tawin Iempridee, Richard J. Jones
Purpose: Lenalidomide, thalidomide, and pomalidomide (LTP) are immunomodulatory agents approved for use in multiple myeloma, but in some settings, especially with alkylating agents, an increase in Hodgkin lymphoma and other secondary primary malignan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4817840270ac7f6eb10e74f00f8a0997
https://doi.org/10.1158/1078-0432.c.6524838
https://doi.org/10.1158/1078-0432.c.6524838
Autor:
Robert Z. Orlowski, Donna M. Weber, Jatin J. Shah, Christopher W. Dawson, Veerabhadran Baladandayuthapani, Heather C. Lin, Shannon C. Kenney, Janet E. Mertz, Hans C. Lee, Xiaobin Wang, Tawin Iempridee, Richard J. Jones
EBV viral loads in patient serum samples on a LEN, THAL, DEX combination.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::629461786c18bed956c74e5894a3616d
https://doi.org/10.1158/1078-0432.22461615
https://doi.org/10.1158/1078-0432.22461615