Zobrazeno 1 - 10
of 226
pro vyhledávání: '"CHRISTOPH M. TANG"'
Publikováno v:
mSphere, Vol 8, Iss 6 (2023)
ABSTRACTNeisseria gonorrhoeae causes sexually transmitted infection (STI) gonorrhoea and is on the WHO critical list due to increasing antimicrobial resistance (AMR). The bacterium can carry a conjugative plasmid, pConj, which prevents the use of tet
Externí odkaz:
https://doaj.org/article/bcc701fab6974d8299d2c069174a4a61
Publikováno v:
PLoS Genetics, Vol 19, Iss 5, p e1010743 (2023)
Plasmids are diverse extrachromosomal elements significantly that contribute to interspecies dissemination of antimicrobial resistance (AMR) genes. However, within clinically important bacteria, plasmids can exhibit unexpected narrow host ranges, a p
Externí odkaz:
https://doaj.org/article/40f3ec4adcdd4292ab94a0c56d1e67ac
Publikováno v:
Military Medical Research, Vol 9, Iss 1, Pp 1-11 (2022)
Abstract Bacteria can evolve rapidly by acquiring new traits such as virulence, metabolic properties, and most importantly, antimicrobial resistance, through horizontal gene transfer (HGT). Multidrug resistance in bacteria, especially in Gram-negativ
Externí odkaz:
https://doaj.org/article/d5134c4c31ad4284b79cb6dbaa5a1daf
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Neisseria meningitidis and Neisseria gonorrhoeae are two obligate human pathogens that have evolved to be uniquely adapted to their host. The meningococcus is frequently carried asymptomatically in the nasopharynx, while gonococcal infection of the u
Externí odkaz:
https://doaj.org/article/bc051f35d43341d4acbd2c7109ef12c0
Autor:
Yang Su, Jianhui Li, Wenting Zhang, Jinjing Ni, Rui Huang, Zuoqiang Wang, Sen Cheng, Yue Wang, Zhixin Tian, Qiuxiang Zhou, Donghai Lin, Wenjuan Wu, Christoph M. Tang, Xiaoyun Liu, Jie Lu, Yu-Feng Yao
Publikováno v:
mBio, Vol 12, Iss 5 (2021)
Posttranslational modifications (PTMs) play an important role in regulating enzyme activities, protein-protein interactions, or DNA-protein recognition and, consequently, modulate many biological functions. We demonstrated that PhoP, the response reg
Externí odkaz:
https://doaj.org/article/19f014700315414cbc5144d4ac08ed96
Autor:
Sarah G Earle, Mariya Lobanovska, Hayley Lavender, Changyan Tang, Rachel M Exley, Elisa Ramos-Sevillano, Douglas F Browning, Vasiliki Kostiou, Odile B Harrison, Holly B Bratcher, Gabriele Varani, Christoph M Tang, Daniel J Wilson, Martin C J Maiden
Publikováno v:
PLoS Pathogens, Vol 17, Iss 10, p e1009992 (2021)
Many invasive bacterial diseases are caused by organisms that are ordinarily harmless components of the human microbiome. Effective interventions against these microbes require an understanding of the processes whereby symbiotic or commensal relation
Externí odkaz:
https://doaj.org/article/0b6f3dfc4de74b43a1339c59c7591f44
Autor:
Rafael Custodio, Rhian M Ford, Cara J Ellison, Guangyu Liu, Gerda Mickute, Christoph M Tang, Rachel M Exley
Publikováno v:
eLife, Vol 10 (2021)
Type VI Secretion Systems (T6SSs) are widespread in bacteria and can dictate the development and organisation of polymicrobial ecosystems by mediating contact dependent killing. In Neisseria species, including Neisseria cinerea a commensal of the hum
Externí odkaz:
https://doaj.org/article/166cfad48bbd41369d9889d0d64efae5
Publikováno v:
PLoS Pathogens, Vol 16, Iss 3, p e1008372 (2020)
It is increasingly being recognised that the interplay between commensal and pathogenic bacteria can dictate the outcome of infection. Consequently, there is a need to understand how commensals interact with their human host and influence pathogen be
Externí odkaz:
https://doaj.org/article/3c5f8ce28d814eac934e4a4d11f68d78
Autor:
Emeline Lawarée, Gytis Jankevicius, Charles Cooper, Ivan Ahel, Stephan Uphoff, Christoph M. Tang
Publikováno v:
Cell Reports, Vol 30, Iss 5, Pp 1373-1384.e4 (2020)
Summary: ADP-ribosylation of proteins is crucial for fundamental cellular processes. Despite increasing examples of DNA ADP-ribosylation, the impact of this modification on DNA metabolism and cell physiology is unknown. Here, we show that the DarTG t
Externí odkaz:
https://doaj.org/article/3e3003a16285442cb7ec8d952a71ba36
Autor:
Giulia Pilla, Tao Wu, Christen Grassel, Jonathan Moon, Jennifer Foulke-Abel, Christoph M. Tang, Eileen M. Barry
Publikováno v:
Pathogens, Vol 10, Iss 9, p 1079 (2021)
Shigella is a leading cause of bacillary dysentery worldwide, responsible for high death rates especially among children under five in low–middle income countries. Shigella sonnei prevails in high-income countries and is becoming prevalent in indus
Externí odkaz:
https://doaj.org/article/c79461ec0421489d93f1b7bed99aaaa9