Zobrazeno 1 - 10
of 21
pro vyhledávání: '"CHRISTINE M. BOYLE"'
Autor:
S. M. Shahjahan Miah, Sandra Lelias, Andres H. Gutierrez, Mitchell McAllister, Christine M. Boyle, Lenny Moise, Anne S. De Groot
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Pathogens escape host defenses by T-cell epitope mutation or deletion (immune escape) and by simulating the appearance of human T cell epitopes (immune camouflage). We identified a highly conserved, human-like T cell epitope in non-structural protein
Externí odkaz:
https://doaj.org/article/b15d41c0df4c413b9ef411ccc4ae045f
Autor:
Leonard Moise, Lauren M. Meyers, Hyesun Jang, Mayara Grizotte-Lake, Christine M. Boyle, Bethany McGonnigal, Pan Ge, Ted M. Ross, Anne S. De Groot
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 18, Iss 4 (2022)
Strategies that improve influenza vaccine immunogenicity are critical for the development of vaccines for pandemic preparedness. Hemagglutinin (HA)-specific CD4+ T cell epitopes support protective B cell responses against seasonal influenza. However,
Externí odkaz:
https://doaj.org/article/c0c0dd6971c34458b782b56c5cbec279
Autor:
Lauren M. Meyers, Andres H. Gutiérrez, Christine M. Boyle, Frances Terry, Bethany G. McGonnigal, Andres Salazar, Michael F. Princiotta, Wiliam D. Martin, Anne S. De Groot, Leonard Moise
Publikováno v:
npj Vaccines, Vol 6, Iss 1, Pp 1-14 (2021)
Abstract Natural and vaccine-induced SARS-CoV-2 immunity in humans has been described but correlates of protection are not yet defined. T cells support the SARS-CoV-2 antibody response, clear virus-infected cells, and may be required to block transmi
Externí odkaz:
https://doaj.org/article/d615a4694c9742dd8d5bff1c0123276c
Autor:
Leonard Moise, Bethany M. Biron, Christine M. Boyle, Nese Kurt Yilmaz, Hyesun Jang, Celia Schiffer, Ted M. Ross, William D. Martin, Anne S. De Groot
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 14, Iss 9, Pp 2203-2207 (2018)
The delayed availability of vaccine during the 2009 H1N1 influenza pandemic created a sense of urgency to better prepare for the next influenza pandemic. Advancements in manufacturing technology, speed and capacity have been achieved but vaccine effe
Externí odkaz:
https://doaj.org/article/854fbb36eaa049ba956ce8e78a7b5551
Autor:
Anja Scholzen, Guilhem Richard, Leonard Moise, Laurie A. Baeten, Patrick M. Reeves, William D. Martin, Timothy A. Brauns, Christine M. Boyle, Susan Raju Paul, Richard Bucala, Richard A. Bowen, Anja Garritsen, Anne S. De Groot, Ann E. Sluder, Mark C. Poznansky
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Coxiella burnetii, the causative agent of Q fever, is a Gram-negative intracellular bacterium transmitted via aerosol. Regulatory approval of the Australian whole-cell vaccine Q-VAX® in the US and Europe is hindered by reactogenicity in previously e
Externí odkaz:
https://doaj.org/article/8f3d7cea8fe147daa18cf4076819e78a
Autor:
Bethany G. McGonnigal, Anne S. De Groot, Andres H. Gutierrez, Leonard Moise, Wiliam D. Martin, Andres Salazar, Lauren M. Meyers, Frances Terry, Christine M. Boyle, Michael F. Princiotta
Publikováno v:
npj Vaccines, Vol 6, Iss 1, Pp 1-14 (2021)
Natural and vaccine-induced SARS-CoV-2 immunity in humans has been described but correlates of protection are not yet defined. T cells support the SARS-CoV-2 antibody response, clear virus-infected cells, and may be required to block transmission. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ada08a3bbfa81d36347141c4fc9dbba1
https://doaj.org/article/d615a4694c9742dd8d5bff1c0123276c
https://doaj.org/article/d615a4694c9742dd8d5bff1c0123276c
Autor:
Anne S. De Groot, Hyesun Jang, Ted M. Ross, Christine M. Boyle, Lauren M. Meyers, Leonard Moise
Publikováno v:
Human Vaccines & Immunotherapeutics
article-version (VoR) Version of Record
article-version (VoR) Version of Record
The influenza hemagglutinin (HA) isolated from avian H7N9 influenza virus strains elicit weak immune responses. This low immunogenicity may be due to a regulatory T cell (Treg)–stimulating epitopes in HA from the H7N9 isolate A/Anhui/1/2013 (Anh/13
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::100ec5bcd0f02c12947c5a54dcf15c8f
https://pubmed.ncbi.nlm.nih.gov/32783766
https://pubmed.ncbi.nlm.nih.gov/32783766
Autor:
Anne S. De Groot, Hyesun Jang, Leonard Moise, Bethany M. Biron, William D. Martin, Nese Kurt Yilmaz, Christine M. Boyle, Ted M. Ross, Celia A. Schiffer
Publikováno v:
Human Vaccines & Immunotherapeutics
The delayed availability of vaccine during the 2009 H1N1 influenza pandemic created a sense of urgency to better prepare for the next influenza pandemic. Advancements in manufacturing technology, speed and capacity have been achieved but vaccine effe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae80e5d1d34b56d0768c0c8aea9eef24
http://europepmc.org/articles/PMC6183197
http://europepmc.org/articles/PMC6183197
Autor:
Anja, Scholzen, Guilhem, Richard, Leonard, Moise, Laurie A, Baeten, Patrick M, Reeves, William D, Martin, Timothy A, Brauns, Christine M, Boyle, Susan, Raju Paul, Richard, Bucala, Richard A, Bowen, Anja, Garritsen, Anne S, De Groot, Ann E, Sluder, Mark C, Poznansky
Publikováno v:
Frontiers in Immunology
Coxiella burnetii, the causative agent of Q fever, is a Gram-negative intracellular bacterium transmitted via aerosol. Regulatory approval of the Australian whole-cell vaccine Q-VAX® in the US and Europe is hindered by reactogenicity in previously e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2010f286e6bc7fd2b3f2f29fed05db61
https://pubmed.ncbi.nlm.nih.gov/30828331
https://pubmed.ncbi.nlm.nih.gov/30828331
Autor:
Ryan Tassone, Timothy J. Messitt, Christine M. Boyle, Amber J. Vincelli, Ted M. Ross, Leonard Moise, William J. Martin, Lauren Levitz, Anne S. De Groot, Paul M. Knopf
Publikováno v:
Immunology and cell biology
Complement fragment C3d covalently attached to antigens enhances immune responses, particularly for antigens lacking T-cell epitopes. Enhancement has been attributed to receptor cross-linking between complement receptor CR2 (CD21) and polysaccharide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20ec3b9b87dbfd92b2cea1de2ba3c42c
https://doi.org/10.1038/icb.2014.89
https://doi.org/10.1038/icb.2014.89