Zobrazeno 1 - 10
of 164
pro vyhledávání: '"CHRISTIAN IDEL"'
Autor:
Marie-Nicole Theodoraki, Diana Huber, Linda Hofmann, Lotte Werner, Christian Idel, Jonas Fleckner, Kirstin Plötze-Martin, Lutz Schütt, Cornelia Brunner, Reinhard Depping, Thomas K. Hoffmann, Karl-Ludwig Bruchhage, Ralph Pries
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Background Exosomes are closely associated with different aspects of tumor-progression in patients with head and neck squamous cell carcinoma (HNSCC), such as angiogenesis or immune regulation. As extracellular vesicles they are involved in
Externí odkaz:
https://doaj.org/article/8febd94011434cd39ad0e08df9476fce
Autor:
Christian Idel, Jonas Fleckner, Kirstin Plötze-Martin, Lotte Werner, Dirk Rades, Marie-Nicole Theodoraki, Linda Hofmann, Diana Huber, Anke Leichtle, Thomas K. Hoffmann, Karl-Ludwig Bruchhage, Ralph Pries
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background Head and neck squamous cell carcinoma (HNSCC) represents a common and heterogeneous malignancy of the oral cavity, pharynx and larynx. Surgery and radio(chemo)therapy are the standard treatment options and also have great influenc
Externí odkaz:
https://doaj.org/article/00d90afcd16e4cecbcf18e983b6db96a
Autor:
Julius M. Vahl, Gabriele Nagel, Tsima Abou Kors, Matthias Brand, Adrian vonWitzleben, Michael Sonntag, Ayla Grages, Marie N. Theodoraki, Jens Greve, Michael Denkinger, Dhayana Dallmeier, Christian Idel, Stephan Stilgenbauer, Thomas K. Hoffmann, Simon Laban
Publikováno v:
Cancer Medicine, Vol 12, Iss 23, Pp 21426-21435 (2023)
Abstract Introduction Demographics are important prognostic factors in malignant diseases. A nationwide analysis concerning the prognostic impact of demographics in head and neck cancer (HNC) patients (HNCP) has not been performed previously. Methods
Externí odkaz:
https://doaj.org/article/403267fe0932404bb41475658f084ee6
Autor:
Julius M. Vahl, Gabriele Nagel, Ayla Grages, Matthias Brand, Adrian vonWitzleben, Michael Sonntag, Marie‐Nicole Theodoraki, Jens Greve, Tsima Aboukors, Michael Denkinger, Dhayana Dallmeier, Christian Idel, Thomas K. Hoffmann, Simon Laban
Publikováno v:
Cancer Medicine, Vol 12, Iss 18, Pp 18826-18836 (2023)
Abstract Background Demographic development in rural and urban areas differs substantially. Demographics and access to specialized head and neck cancer centers may affect head and neck cancer patients' (HNCP) outcomes. Here, we compare epidemiologica
Externí odkaz:
https://doaj.org/article/a1465fdd240b4ed1b704c84412fc0dbc
Autor:
Martina Aguiar Bucsai, Christian Idel, Barbara Wollenberg, Christine Mannhalter, Admar Verschoor
Publikováno v:
Platelets, Vol 33, Iss 8, Pp 1192-1198 (2022)
We aimed to investigate the effects of integrin αIIbβ3 inhibitor tirofiban on hallmarks of platelet activation, degranulation, and aggregation during its use to analyze activated but non-complexed platelets via flow cytometry. To do so, we used was
Externí odkaz:
https://doaj.org/article/67d154783c2d4217a594f18f8ee8fe79
Autor:
Philipp Jurmeister, Stefanie Glöß, Renée Roller, Maximilian Leitheiser, Simone Schmid, Liliana H. Mochmann, Emma Payá Capilla, Rebecca Fritz, Carsten Dittmayer, Corinna Friedrich, Anne Thieme, Philipp Keyl, Armin Jarosch, Simon Schallenberg, Hendrik Bläker, Inga Hoffmann, Claudia Vollbrecht, Annika Lehmann, Michael Hummel, Daniel Heim, Mohamed Haji, Patrick Harter, Benjamin Englert, Stephan Frank, Jürgen Hench, Werner Paulus, Martin Hasselblatt, Wolfgang Hartmann, Hildegard Dohmen, Ursula Keber, Paul Jank, Carsten Denkert, Christine Stadelmann, Felix Bremmer, Annika Richter, Annika Wefers, Julika Ribbat-Idel, Sven Perner, Christian Idel, Lorenzo Chiariotti, Rosa Della Monica, Alfredo Marinelli, Ulrich Schüller, Michael Bockmayr, Jacklyn Liu, Valerie J. Lund, Martin Forster, Matt Lechner, Sara L. Lorenzo-Guerra, Mario Hermsen, Pascal D. Johann, Abbas Agaimy, Philipp Seegerer, Arend Koch, Frank Heppner, Stefan M. Pfister, David T. W. Jones, Martin Sill, Andreas von Deimling, Matija Snuderl, Klaus-Robert Müller, Erna Forgó, Brooke E. Howitt, Philipp Mertins, Frederick Klauschen, David Capper
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Sinonasal tumour diagnosis can be complicated by the heterogeneity of disease and classification systems. Here, the authors use machine learning to classify sinonasal undifferentiated carcinomas into 4 molecular classe with differences in differentia
Externí odkaz:
https://doaj.org/article/6b6e398cca1d45b0ab123d7e7294892a
Autor:
Christina Polasky, Kristin Loyal, Christian Idel, David Wetterauer, Mathias Heidemann, Karl-Ludwig Bruchhage, Ralph Pries
Publikováno v:
Rhinology Online, Vol 4, Iss 4, Pp 194-202 (2021)
Background: Chronic rhinosinusitis (CRS) affects about 10% of the european population causing considerable disease burden. The inflammatory microenvironment is mainly Th2 driven, but the impact of monocytes is still poorly understood. Aim of this stu
Externí odkaz:
https://doaj.org/article/930a2e9359d148659330ed493409be87
Autor:
Christiane Kuempers, Tobias Jagomast, Rosemarie Krupar, Finn-Ole Paulsen, Carsten Heidel, Julika Ribbat-Idel, Christian Idel, Bruno Märkl, Martin Anlauf, Sabina Berezowska, Markus Tiemann, Hans Bösmüller, Falko Fend, Barbara Kalsdorf, Sabine Bohnet, Eva Dreyer, Verena Sailer, Jutta Kirfel, Sven Perner
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Rovalpituzumab tesirine (Rova-T), an antibody-drug conjugate directed against Delta-like protein 3 (DLL3), is under development for patients with small cell lung cancer (SCLC). DLL3 is expressed on the majority of SCLC samples. Because SCLC is rarely
Externí odkaz:
https://doaj.org/article/2f2a6251c4574098908108fee406f2a3
Autor:
Christian Idel, Julika Ribbat-Idel, Luise Klapper, Rosemarie Krupar, Karl-Ludwig Bruchhage, Eva Dreyer, Dirk Rades, Christina Polasky, Anne Offermann, Jutta Kirfel, Sven Perner, Barbara Wollenberg
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
BackgroundHead and neck squamous cell carcinomas (HNSCCs) have a very moderate response rate to immune checkpoint inhibitor (ICI) treatment compared to other cancer types. Lacking predictive markers for treatment response, we analyzed the immune stat
Externí odkaz:
https://doaj.org/article/90f3e170be3a4df9b68b0ce402e8f27c
Autor:
Christian Idel, Christina Polasky, Julika Ribbat-Idel, Kristin Loyal, Sven Perner, Dirk Rades, Karl-Ludwig Bruchhage, Ralph Pries
Publikováno v:
Biomedicines, Vol 10, Iss 6, p 1363 (2022)
Background: Patients with human papilloma virus (HPV)-related oropharyngeal cancer have a better prognosis than nonvirally associated patients, most likely because of better immune responses. Increased infiltration of T lymphocytes into the oropharyn
Externí odkaz:
https://doaj.org/article/08007c53308b4da691c083c37d84c972