Zobrazeno 1 - 10
of 539
pro vyhledávání: '"CHOLESTEROL-DEPENDENT CYTOLYSIN"'
Autor:
Tjokorda Istri Pramitasuri, Ni Made Susilawathi, Ni Made Adi Tarini, AA Raka Sudewi, Matthew C Evans
Publikováno v:
AIMS Microbiology, Vol 9, Iss 4, Pp 647-667 (2023)
Bacterial meningitis is a catastrophic nervous system disorder with high mortality and wide range of morbidities. Some of the meningitis-causing bacteria occupy cholesterol dependent cytolysins (CDCs) to increase their pathogenicity and arrange immun
Externí odkaz:
https://doaj.org/article/400f791611a1460896b8d938f0ec6b77
Akademický článek
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Autor:
Atsushi Tabata, Airi Matsumoto, Ai Fujimoto, Kazuto Ohkura, Takuya Ikeda, Hiroki Oda, Shuto Yokohata, Miho Kobayashi, Toshifumi Tomoyasu, Ayuko Takao, Hisashi Ohkuni, Hideaki Nagamune
Publikováno v:
Journal of Oral Microbiology, Vol 14, Iss 1 (2022)
Background Some strains of Streptococcus mitis exhibit β-hemolysis due to the β-hemolytic activity of cholesterol-dependent cytolysin (CDC). Recently, a gene encoding an atypical lectinolysin-related CDC was found in S. mitis strain Nm-76. However,
Externí odkaz:
https://doaj.org/article/208d1e0b45f34ca692c9b47fb60dc846
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 5 (2022)
ABSTRACT Pyolysin (PLO) is secreted by Trueperella pyogenes as a water-soluble monomer after forming transmembrane β-barrel channels in the cell membrane by binding cholesterol. Two significantly conserved residues at domain 1 of PLO are mutated, wh
Externí odkaz:
https://doaj.org/article/06ac3bae7ec94ee789ef5ef1d94716f3
Autor:
Conall McGuinness, James C Walsh, Charles Bayly-Jones, Michelle A Dunstone, Michelle P Christie, Craig J Morton, Michael W Parker, Till Böcking
Publikováno v:
eLife, Vol 11 (2022)
The cholesterol-dependent cytolysin perfringolysin O (PFO) is secreted by Clostridium perfringens as a bacterial virulence factor able to form giant ring-shaped pores that perforate and ultimately lyse mammalian cell membranes. To resolve the kinetic
Externí odkaz:
https://doaj.org/article/9c52c20469604be898a9fcf4065fd2d3
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Pneumolysin (PLY) is a pore-forming toxin produced by the human pathobiont Streptococcus pneumoniae, the major cause of pneumonia worldwide. PLY, a key pneumococcal virulence factor, can form transmembrane pores in host cells, disrupting plasma membr
Externí odkaz:
https://doaj.org/article/ca95d0c13db840e7888796e9c37191f4
Autor:
Thomas J. R. Ormsby, Sian E. Owens, Liam Clement, Tom J. Mills, James G. Cronin, John J. Bromfield, Iain Martin Sheldon
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Many species of bacteria produce toxins such as cholesterol-dependent cytolysins that form pores in cell membranes. Membrane pores facilitate infection by releasing nutrients, delivering virulence factors, and causing lytic cell damage - cytolysis. O
Externí odkaz:
https://doaj.org/article/142f04d5f4314de7ab090c03825dae45
Akademický článek
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Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The Vibrio vulnificus (V. vulnificus) hemolysin (VVH) is a pore-forming cholesterol-dependent cytolysin (CDC). Although there has been some debate surrounding the in vivo virulence effects of the VVH, it is becoming increasingly clear that it drives
Externí odkaz:
https://doaj.org/article/959b10757e8b4c6f8bb4d71c7897bb35
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Streptococcus pneumoniae is an opportunistic pathogen responsible for widespread illness and is a major global health issue for children, the elderly, and the immunocompromised population. Pneumolysin (PLY) is a cholesterol-dependent cytolysin (CDC)
Externí odkaz:
https://doaj.org/article/72f4ec4bea3149f0934c351d5943b7d6