Zobrazeno 1 - 10
of 2 061
pro vyhledávání: '"CHOLESTATIC LIVER"'
Autor:
Ana Isabel Ferreira, Vítor Macedo Silva, Cátia Arieira, Sofia Xavier, Joana Magalhães, José Cotter
Publikováno v:
GE: Portuguese Journal of Gastroenterology, Pp 1-9 (2024)
Introduction: Propafenone is a widely used class Ic antiarrhythmic drug that is mainly metabolised by the liver. Hepatotoxicity associated with propafenone is rare, with only a few clinical cases reported in the literature. Case Presentation: We pres
Externí odkaz:
https://doaj.org/article/c22d96464c0741d19a313841aefa4c35
Autor:
Connie Chan, Mateus Lemos, Peter Finnegan, William Gagnon, Richard Dean, Maryam Yazdanafar, Joseph Zepeda, Marie-Claude Vohl, Michael Trauner, Joshua R. Korzenik, Olivier Barbier, Maria L. Marco, Christopher L. Bowlus
Publikováno v:
JHEP Reports, Vol 6, Iss 12, Pp 101188- (2024)
Background & Aims: Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease with a strong association with inflammatory bowel disease and variable disease progression. We aimed to gain insights into the role of fecal bile acids (BA
Externí odkaz:
https://doaj.org/article/546e251f97cd4795b9b729ceb8a4415f
Autor:
Lingyi Wu, Jianchun Zhou, An Zhou, Yuanyuan Lei, Li Tang, Shiping Hu, Sumin Wang, Xu Xiao, Qiao Chen, Dianji Tu, Cheng Lu, Yi Lai, Yiding Li, Xiao Zhang, Bo Tang, Shiming Yang
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
Gut microbiota dysbiosis is involved in cholestatic liver diseases. However, the mechanisms remain to be elucidated. The purpose of this study was to examine the effects and mechanisms of Lactobacillus acidophilus (L. acidophilus) on cholestatic live
Externí odkaz:
https://doaj.org/article/0948326be2cc4839aa162f7b18f1d757
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Emodin (EMO) has the effect of anti-cholestasis induced by alpha-naphthylisothiocyanate (ANIT). But its mechanism is still unclear. The farnesoid X receptor (Fxr) is the master bile acid nuclear receptor. Recent studies have reported that Si
Externí odkaz:
https://doaj.org/article/99ba29c880a7474cb170cf025f64f9c1
Autor:
Dayan sun, Chuanping Xie, Yong Zhao, Junmin Liao, Shuangshuang Li, Yanan Zhang, Dingding Wang, Kaiyun Hua, Yichao Gu, Jingbin Du, Guoxian Huang, Jinshi Huang
Publikováno v:
Molecular Medicine, Vol 30, Iss 1, Pp 1-16 (2024)
Abstract Cholestatic liver diseases (CLD) are characterized by impaired normal bile flow, culminating in excessive accumulation of toxic bile acids. The majority of patients with CLD ultimately progress to liver cirrhosis and hepatic failure, necessi
Externí odkaz:
https://doaj.org/article/bec822a5f6ad4295afcfc57946bd54c3
Autor:
Lili Cao, Xiuxin Ling, Jianguo Yan, Danni Feng, Yi Dong, Zhiqiang Xu, Fuchuan Wang, Shishu Zhu, Yinjie Gao, Zhenhua Cao, Min Zhang
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 19, Iss 1, Pp 1-11 (2024)
Abstract Background ABCB4 gene-related cholestatic liver diseases have a wide spectrum of clinical and genetic variations. The correlation between genotype and clinical phenotype still unclear. This study retrospectively analyzed the clinical and pat
Externí odkaz:
https://doaj.org/article/1c6a22964a1c4c518ae6be968f22b7a8
Publikováno v:
Cells, Vol 13, Iss 23, p 1997 (2024)
The aim of this review is to explore the potential of new regenerative medicine approaches in the treatment of cholestatic liver fibrosis. Cholestatic liver diseases, such as primary biliary cholangitis (PBC), primary sclerosing cholangitis (PSC), an
Externí odkaz:
https://doaj.org/article/3b09a5f8bd564934b4dd980ce67a1eab
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Salidroside (SAL), a phenylpropanoid bioactive compound, has various pharmacological properties, including antioxidant, anti-inflammatory, and hepatoprotective effects. However, the pharmacological effects and mechanisms of action of SAL on cholestat
Externí odkaz:
https://doaj.org/article/06a3f5b996d9409788113dcc38e7cf1c
Publikováno v:
中西医结合护理, Vol 10, Iss 1, Pp 66-70 (2024)
Objective To observe the effect of modified Traditional Chinese Medicine external application in the treatment of pruritus in patients with chronic cholestatic liver disease, and to improve the quality of Tradition Chinese Medicine nursing of liver d
Externí odkaz:
https://doaj.org/article/da5ebcc38743442196cb55e2a9422ddd
Autor:
Antonia Greimel, Katharina Habler, Caroline Gräfe, Nils Maciuga, Clara Isabell Brozat, Michael Vogeser, Michael Zoller, Felix L. Happich, Uwe Liebchen, Sandra Frank, Michael Paal, Christina Scharf
Publikováno v:
Annals of Intensive Care, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Background The release of toxic bile acids (BAs) in the blood of critically ill patients with cholestatic liver dysfunction might lead to the damage of various organs. Their extracorporeal elimination using the cytokine adsorber Cytosorb® (
Externí odkaz:
https://doaj.org/article/81795b989bbf4ba3a0fc1bb44fb81816