Zobrazeno 1 - 10
of 529
pro vyhledávání: '"CHIARA CREMOLINI"'
Autor:
Leonardo Provenzano, Yong Xiang Gwee, Veronica Conca, Sara Lonardi, Silvia Bozzarelli, Emiliano Tamburini, Alessandro Passardi, Alberto Zaniboni, Federica Tosi, Giuseppe Aprile, Vincenzo Nasca, Alessandra Boccaccino, Margherita Ambrosini, Guglielmo Vetere, Martina Carullo, Marcello Guaglio, Luigi Battaglia, Joseph Jonathan Zhao, Daryl Kai Ann Chia, Wei Peng Yong, Patrick Tan, Jimmy So, Guowei Kim, Asim Shabbir, Chin-Ann Johnny Ong, Francesco Casella, Chiara Cremolini, Maria Bencivenga, Raghav Sundar, Filippo Pietrantonio
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 16 (2024)
Background: Ascites is common in advanced gastrointestinal cancers with peritoneal metastases (PM) and negatively impacts patient survival. No study to date has specifically evaluated the relationship between ascites, PM and survival outcomes in meta
Externí odkaz:
https://doaj.org/article/bc9281818c7f47ceb2097603de735614
Autor:
Fausto Petrelli, Maria Antista, Lorenzo Dottorini, Alessandro Russo, Marcella Arru, Roberta Invernizzi, Mariangela Manzoni, Chiara Cremolini, Alberto Zaniboni, Ornella Garrone, Gianluca Tomasello, Michele Ghidini
Publikováno v:
Heliyon, Vol 10, Iss 17, Pp e36497- (2024)
Introduction: The molecular profile of colorectal cancer (CRC) plays a crucial role in understanding patient prognosis and treatment response. Within CRC, a distinct subgroup can be identified by the presence of the BRAF V600E mutation. This specific
Externí odkaz:
https://doaj.org/article/4eb10c4254cd437fbfa1d55b7078f35a
Autor:
Marco Maria Germani, Guglielmo Vetere, Mirella Giordano, Paolo Ciracì, Iolanda Capone, Elena Tamborini, Elena Conca, Adele Busico, Filippo Pietrantonio, Vittoria Matilde Piva, Alessandra Boccaccino, Francesca Simionato, Martina Bortolot, Paolo Manca, Sara Lonardi, Veronica Conca, Beatrice Borelli, Martina Carullo, Marzia Del Re, Gabriella Fontanini, Daniele Rossini, Chiara Cremolini
Publikováno v:
Frontiers in Oncology, Vol 13 (2024)
BackgroundRetreatment with anti-EGFR monoclonal antibodies is a promising strategy in patients with RAS/BRAF wild-type (wt) metastatic colorectal cancer (mCRC) who achieved benefit from previous anti-EGFR exposure upon exclusion of mutations in RAS/B
Externí odkaz:
https://doaj.org/article/119b59c1dc1d407698a8eee5621f82dc
Publikováno v:
OncoImmunology, Vol 12, Iss 1 (2023)
ABSTRACTIn the last decade, a plethora of immunotherapeutic strategies have been designed to modulate the tumor immune microenvironment. In particular, immune checkpoint (IC) blockade therapies present the most promising advances made in cancer treat
Externí odkaz:
https://doaj.org/article/09f80004c60e4f23ae689021c50d6ce1
Autor:
Alessandro Brancatella, Laura Pierotti, Nicola Viola, Isabella Lupi, Lucia Montanelli, Chiara Cremolini, Paolo Piaggi, Antonio Chella, Andrea Antonuzzo, Daniele Sgrò, Lucia Antonangeli, Chiara Sardella, Sandra Brogioni, Claudio Marcocci, Ferruccio Santini, Francesco Latrofa
Publikováno v:
European Thyroid Journal, Vol 11, Iss 4, Pp 1-8 (2023)
Objective: Destructive thyroiditis is the most common endocrine immune-related adverse event (iRAEs) in patients treated with anti-PD1/PD-L1 agents. Given its self-limited course, current guidelines recommend no treatment for this iRAE. Nevertheless,
Externí odkaz:
https://doaj.org/article/eaa5458e85054d6bb79ef3dbdfc0afa7
Autor:
Chiara Cremolini, Daniele Rossini, Sara Lonardi, Filippo Pietrantonio, Gianluca Masi, Roberto Moretto, Alessandra Boccaccino, Jerome Galon, Jacques Fieschi, Stefano Tamberi, Gabriella Fontanini, Lisa Salvatore, Clara Ugolini, Alboukadel Kassambara, Emiliano Tamburini, Veronica Conca, Aurélie Catteau, Carlotta Antoniotti, Mirella Giordano, Agnese Proietti, Anello Marcello Poma
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 4 (2023)
Background Tumor immune cells influence the efficacy of immune-checkpoint inhibitors (ICIs) and many efforts aim at identifying features of tumor immune microenvironment able to predict benefit from ICIs in proficient mismatch repair (pMMR)/microsate
Externí odkaz:
https://doaj.org/article/bd3dc2d98d4c4c5d878cb9d38164d9cc
Autor:
Jingyuan Wang, Joshua Millstein, Yan Yang, Sebastian Stintzing, Hiroyuki Arai, Francesca Battaglin, Natsuko Kawanishi, Shivani Soni, Wu Zhang, Christoph Mancao, Chiara Cremolini, Tianshu Liu, Volker Heinemann, Alfredo Falcone, Lin Shen, Heinz-Josef Lenz
Publikováno v:
EClinicalMedicine, Vol 57, Iss , Pp 101827- (2023)
Summary: Background: Antiangiogenic drug (AAD)-triggered oxygen and nutrient depletion through suppression of angiogenesis switches glucose-dependent to lipid-dependent metabolism. Blocking fatty acid oxidation can enhance AAD-mediated anti-tumor eff
Externí odkaz:
https://doaj.org/article/369c666a028b48c587ea629fca3a1f39
Autor:
Chiara Cremolini, Clara Montagut, Philippe Ronga, Filippo Venturini, Kensei Yamaguchi, Sebastian Stintzing, Alberto Sobrero
Publikováno v:
Frontiers in Oncology, Vol 12 (2023)
In patients with RAS wild-type metastatic colorectal cancer (mCRC), an anti-epidermal growth factor receptor (EGFR) monoclonal antibody plus chemotherapy is a standard option for treatment in the first-line setting. Patients who progress while on tre
Externí odkaz:
https://doaj.org/article/1777e610457b4d03857d820d434f40e8
Autor:
Chiara Cremolini, Francesca Corti, Elisabetta Fenocchio, Michael J Overman, Lisa Salvatore, Rossana Intini, Priya Jayachandran, Javier Ros, Maria Elena Elez, Aakash Tushar Shah, Rosalba Miceli, Monica Niger, Giacomo Mazzoli, Francesco Barretta
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 1 (2023)
Background Immune checkpoint inhibitors (ICIs) show a tremendous activity in microsatellite instability-high (MSI-H) metastatic colorectal cancer (mCRC), but a consistent fraction of patients does not respond. Prognostic/predictive markers are needed
Externí odkaz:
https://doaj.org/article/7d567d1042404b5e91439f87cbff2736
Autor:
Alberto D'Angelo, Huseyin Kilili, Robert Chapman, Daniele Generali, Ingeborg Tinhofer, Stefano Luminari, Benedetta Donati, Alessia Ciarrocchi, Riccardo Giannini, Roberto Moretto, Chiara Cremolini, Filippo Pietrantonio, Navid Sobhani, Debora Bonazza, Robert Prins, Seung Geun Song, Yoon Kyung Jeon, Giuseppina Pisignano, Mattia Cinelli, Stefan Bagby, Araxi O Urrutia
Publikováno v:
PLoS ONE, Vol 18, Iss 1, p e0280364 (2023)
The immune system plays a central role in the onset and progression of cancer. A better understanding of transcriptional changes in immune cell-related genes associated with cancer progression, and their significance in disease prognosis, is therefor
Externí odkaz:
https://doaj.org/article/f938cdfc26e14aae8bf230153ce01e66