Zobrazeno 1 - 10
of 1 239
pro vyhledávání: '"CHI3L1"'
Autor:
Jingyi Du, Yue Yin, Dong Wu, Can Diao, Tiantian Zhao, Fan Peng, Naigang Li, Dongshuang Wang, Jiaming Shi, Liyan Wang, Liang Kong, Wenjuan Zhou, Aijun Hao
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-21 (2024)
Abstract Demyelination occurs widely in the central nervous system (CNS) neurodegenerative diseases, especially the multiple sclerosis (MS), which with a complex and inflammatory lesion microenvironment inhibiting remyelination. Sirtuin6 (SIRT6), a h
Externí odkaz:
https://doaj.org/article/1c4f60bd008b4ea38486e526657a06ec
Autor:
Chiyu He, Zhihang Hu, Zuyuan Lin, Hao Chen, Chenghao Cao, Jinyan Chen, Xudong Yang, Huigang Li, Wei Shen, Xuyong Wei, Li Zhuang, Shusen Zheng, Xiao Xu, Di Lu
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Background Chitinase-3 like-protein-1 (CHI3L1) is a member of the mammalian chitinase-like proteins and elevated serum CHI3L1 level has been proved to be associated with poor prognosis in hepatocellular carcinoma (HCC). This study aimed to i
Externí odkaz:
https://doaj.org/article/2734b2eb8c0a4357860eeec4aa4e71da
Autor:
Wu Yujie, Zhang Renjia
Publikováno v:
Guoji Yanke Zazhi, Vol 24, Iss 11, Pp 1728-1732 (2024)
AIM: To investigate the correlation between serum levels of secreted frizzled-related protein-4(SFRP-4), chitinase 3-like protein 1(CHI3L1)and diabetic retinopathy(DR)in patients with type 2 diabetes mellitus.METHODS: Prospective study. A total of 10
Externí odkaz:
https://doaj.org/article/c315ccbbe8284c44951df074cd7297aa
Publikováno v:
eLife, Vol 13 (2024)
The balanced gut microbiota in intestinal mucus layer plays an instrumental role in the health of the host. However, the mechanisms by which the host regulates microbial communities in the mucus layer remain largely unknown. Here, we discovered that
Externí odkaz:
https://doaj.org/article/15f4f630e3bc47d2a7f827ae1a666494
Autor:
Angélica Díaz-Basabe, Georgia Lattanzi, Federica Perillo, Chiara Amoroso, Alberto Baeri, Andrea Farini, Yvan Torrente, Giuseppe Penna, Maria Rescigno, Michele Ghidini, Elisa Cassinotti, Ludovica Baldari, Luigi Boni, Maurizio Vecchi, Flavio Caprioli, Federica Facciotti, Francesco Strati
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
The interaction between the gut microbiota and invariant Natural Killer T (iNKT) cells plays a pivotal role in colorectal cancer (CRC). The pathobiont Fusobacterium nucleatum influences the anti-tumor functions of CRC-infiltrating iNKT cells. However
Externí odkaz:
https://doaj.org/article/66cb359407d54355a483324114227811
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-17 (2024)
Abstract Background Previous research has revealed that the 18 glycoside hydrolase gene family (GH18) member Chitinase 3-like 1 (Chi3l1) can regulate osteoclast differentiation and bone resorption. However, its downstream receptors and molecular mech
Externí odkaz:
https://doaj.org/article/3c80589a505f4b1ca588f4110c67eb1b
Publikováno v:
Biochemistry and Biophysics Reports, Vol 37, Iss , Pp 101608- (2024)
Sepsis-induced muscle weakness is a debilitating consequence of prolonged critical illness, often associated with a poor prognosis. While recent research has shown that STAT6 functions as an inhibitor of myogenesis, its role in sepsis-induced muscle
Externí odkaz:
https://doaj.org/article/c498c07470244828b3afd392c7979162
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-18 (2023)
Abstract Background Triple-negative breast cancer (TNBC) development may be associated with tumor immune escape. This study explores whether the CHI3L1/MAF/CTLA4/S100A4 axis affects immune escape in TNBC through interplay with triple-negative breast
Externí odkaz:
https://doaj.org/article/2ebcb74a6d124385881e9d0217925ccb
Autor:
Kecheng Shen, Jiandong Zhu, Shijie Zhou, Xin Jin, Weiwei Zhai, Liang Sun, Jiang Wu, Zhengquan Yu
Publikováno v:
Current Oncology, Vol 30, Iss 10, Pp 8686-8702 (2023)
Background: Glioblastoma multiforme is the most common primary intracranial tumor, with a high degree of malignancy, poor therapeutic effect, and poor prognosis. According to previous studies, CHI3L1 and EMP3 are two independent tumor predictors that
Externí odkaz:
https://doaj.org/article/c62a4a1de5244a56a86556284363d497
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 13, p 7094 (2024)
The role of Chitinase-3-like protein 1 (CHI3L1) in tumor progression has been gradually clarified in different kinds of solid tumors. Hence, we aim to elucidate its prognostic value for glioma. In this study, we analyzed RNA sequencing data combined
Externí odkaz:
https://doaj.org/article/c7d2d02def3e40219c090eaba3f9e9d4