Zobrazeno 1 - 10
of 14 859
pro vyhledávání: '"CHECKPOINT kinase 1"'
Autor:
Etingov I; Department of Molecular Microbiology and Immunology, University of Missouri-Columbia, School of Medicine, Bond Life Sciences Center, Columbia, Missouri, USA., Pintel DJ; Department of Molecular Microbiology and Immunology, University of Missouri-Columbia, School of Medicine, Bond Life Sciences Center, Columbia, Missouri, USA.
Publikováno v:
Journal of virology [J Virol] 2024 Dec 17; Vol. 98 (12), pp. e0088924. Date of Electronic Publication: 2024 Nov 20.
Autor:
Fan J; School of Basic Medical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China; Cixi People's Hospital, Institute of Cixi Biomedical Research, Wenzhou Medical University, Cixi, Ningbo, Zhejiang 315302, China., Du X; School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China., Chen M; School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China., Xu Y; School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China., Xu J; School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China., Lu L; School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China; Department of Emergency, The Second Affiliated Hospital, Wenzhou Medical University, Wenzhou, Zhejiang 325027, China., Zhou S; School of Basic Medical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China., Kong X; School of Basic Medical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China., Xu K; Cixi People's Hospital, Institute of Cixi Biomedical Research, Wenzhou Medical University, Cixi, Ningbo, Zhejiang 315302, China. Electronic address: godxu1987@163.com., Zhang H; School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China; Cixi People's Hospital, Institute of Cixi Biomedical Research, Wenzhou Medical University, Cixi, Ningbo, Zhejiang 315302, China. Electronic address: st.hyz@126.com.
Publikováno v:
International immunopharmacology [Int Immunopharmacol] 2024 Sep 10; Vol. 138, pp. 112521. Date of Electronic Publication: 2024 Jun 24.
Autor:
Wei TW; Department of Cardiology The First Affiliated Hospital of Nanjing Medical University Nanjing China., Shan TK; Department of Cardiology The First Affiliated Hospital of Nanjing Medical University Nanjing China., Wang H; Department of Cardiology The First Affiliated Hospital of Nanjing Medical University Nanjing China., Chen JW; Department of Cardiology The First Affiliated Hospital of Nanjing Medical University Nanjing China., Yang TT; Department of Cardiology The First Affiliated Hospital of Nanjing Medical University Nanjing China., Zhou LH; Department of Cardiology The First Affiliated Hospital of Nanjing Medical University Nanjing China., Zhao D; Department of Cardiology The First Affiliated Hospital of Nanjing Medical University Nanjing China., Sun JT; Department of Cardiology The First Affiliated Hospital of Nanjing Medical University Nanjing China., Wang SB; Department of Cardiology The First Affiliated Hospital of Nanjing Medical University Nanjing China., Gu LF; Department of Cardiology The First Affiliated Hospital of Nanjing Medical University Nanjing China., Du C; Department of Cardiology The First Affiliated Hospital of Nanjing Medical University Nanjing China., Jiang QQ; Department of Cardiology The First Affiliated Hospital of Nanjing Medical University Nanjing China., Sun R; Department of Cardiology The First Affiliated Hospital of Nanjing Medical University Nanjing China., Wang QM; Department of Cardiology The First Affiliated Hospital of Nanjing Medical University Nanjing China., Kong XQ; Department of Cardiology The First Affiliated Hospital of Nanjing Medical University Nanjing China., Lu XH; Department of Cardiovascular Surgery The First Affiliated Hospital of Nanjing Medical University Nanjing China., Sun HL; Department of Cardiovascular Surgery The First Affiliated Hospital of Nanjing Medical University Nanjing China., Xu Y; Department of Radiology The First Affiliated Hospital of Nanjing Medical University Nanjing China., Xie LP; Key Laboratory of Cardiovascular and Cerebrovascular Medicine Key Laboratory of Targeted Intervention of Cardiovascular Disease Collaborative Innovation Center for Cardiovascular Disease Translational Medicine Nanjing Medical University Nanjing China., Gu AH; State Key Laboratory of Reproductive Medicine School of Public Health Nanjing Medical University Nanjing China., Chen F; Department of Biostatistics School of Public Health China International Cooperation Center for Environment and Human Health Nanjing Medical University Nanjing China., Ji Y; Key Laboratory of Cardiovascular and Cerebrovascular Medicine Key Laboratory of Targeted Intervention of Cardiovascular Disease Collaborative Innovation Center for Cardiovascular Disease Translational Medicine Nanjing Medical University Nanjing China., Guo XJ; State Key Laboratory of Reproductive Medicine Department of Histology and Embryology Nanjing Medical University Nanjing China., Wang LS; Department of Cardiology The First Affiliated Hospital of Nanjing Medical University Nanjing China.
Publikováno v:
Journal of the American Heart Association [J Am Heart Assoc] 2024 Jul 02; Vol. 13 (13), pp. e034805. Date of Electronic Publication: 2024 Jun 27.
Autor:
Takeda, Kenji1,2 (AUTHOR) asakasai@kanazawa-med.ac.jp, Sakai-Sakasai, Akiko1 (AUTHOR) takeuchi@kanazawa-med.ac.jp, Kajinami, Kouji2 (AUTHOR), Takeuchi, Masayoshi1 (AUTHOR)
Publikováno v:
Cells (2073-4409). Dec2023, Vol. 12 Issue 24, p2838. 26p.
Autor:
Tian‐Wen Wei, Tian‐Kai Shan, Hao Wang, Jia‐Wen Chen, Tong‐Tong Yang, Liu‐Hua Zhou, Di Zhao, Jia‐Teng Sun, Si‐Bo Wang, Ling‐Feng Gu, Chong Du, Qi‐Qi Jiang, Rui Sun, Qi‐Ming Wang, Xiang‐Qing Kong, Xiao‐Hu Lu, Hao‐Liang Sun, Yi Xu, Li‐Ping Xie, Ai‐Hua Gu, Feng Chen, Yong Ji, Xue‐Jiang Guo, Lian‐Sheng Wang
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 13 (2024)
Background The regenerative capacity of the adult mammalian hearts is limited. Numerous studies have explored mechanisms of adult cardiomyocyte cell‐cycle withdrawal. This translational study evaluated the effects and underlying mechanism of rhCHK1
Externí odkaz:
https://doaj.org/article/756e446bc9464bb993b8a5cc6df3cb19
Checkpoint Kinase 1 Is a Key Signal Transducer of DNA Damage in the Early Mammalian Cleavage Embryo.
Autor:
Baran, Vladimír1 (AUTHOR) baran@saske.sk, Mayer, Alexandra2 (AUTHOR) alexandra.mayer@vfn.cz
Publikováno v:
International Journal of Molecular Sciences. Apr2023, Vol. 24 Issue 7, p6778. 15p.
Autor:
Hu S; Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, 210028, Jiangsu, China; Laboratories of Translational Medicine, Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing, 210028, Jiangsu, China; SkyRun Pharma Co., Ltd., No. 9 Weidi Road, Nanjing, 210046, China., Jiang C; Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, 210028, Jiangsu, China; Laboratories of Translational Medicine, Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing, 210028, Jiangsu, China., Jin Q; Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, 210028, Jiangsu, China; Laboratories of Translational Medicine, Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing, 210028, Jiangsu, China. Electronic address: jqmxy@163.com.
Publikováno v:
European journal of medicinal chemistry [Eur J Med Chem] 2024 Apr 05; Vol. 269, pp. 116351. Date of Electronic Publication: 2024 Mar 24.
Akademický článek
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Autor:
Ali JN Duabil, Christian R Cooper, Esraa Aldujaily, Sarah ER Halford, Sandra Hirschberg, Sidath D Katugampola, George DD Jones
Publikováno v:
Exploration of Targeted Anti-tumor Therapy, Vol 4, Iss 6, Pp 1210-1226 (2023)
Aim: In response to DNA damage the serine/threonine-specific protein kinase checkpoint kinase 1 (CHK1) is activated allowing cells to enter S phase (S) and G2 phase (G2) cell-cycle arrest. CHK1 inhibitors are expected to prevent cells from entering s
Externí odkaz:
https://doaj.org/article/ec7ed657492f40f28f2f810abf6cf0d2
Autor:
Zhang H; Institute of Women, Children and Reproductive Health, Shandong University, 250012, Jinan, China.; State Key Laboratory of Reproductive Medicine and Offspring Health, Shandong University, 250012, Jinan, Shandong, China.; National Research Center for Assisted Reproductive Technology and Reproductive Genetics, Shandong University, 250012, Jinan, Shandong, China.; Key Laboratory of Reproductive Endocrinology (Shandong University), of Ministry of Education, Shandong University, 250012, Jinan, Shandong, China.; Shandong Technology Innovation Center for Reproductive Health, 250012, Jinan, Shandong, China.; Shandong Provincial Clinical Research Center for Reproductive Health, 250012, Jinan, Shandong, China.; Shandong Key Laboratory of Reproductive Medicine, Shandong Provincial Hospital Affiliated to Shandong First Medical University, 250012, Jinan, Shandong, China.; Research Unit of Gametogenesis and Health of ART-Offspring, Chinese Academy of Medical Sciences (No.2021RU001), 250012, Jinan, Shandong, China.; The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Gusu School, Nanjing Medical University, Nanjing, China., Cui Y; Institute of Women, Children and Reproductive Health, Shandong University, 250012, Jinan, China.; State Key Laboratory of Reproductive Medicine and Offspring Health, Shandong University, 250012, Jinan, Shandong, China.; National Research Center for Assisted Reproductive Technology and Reproductive Genetics, Shandong University, 250012, Jinan, Shandong, China.; Key Laboratory of Reproductive Endocrinology (Shandong University), of Ministry of Education, Shandong University, 250012, Jinan, Shandong, China.; Shandong Technology Innovation Center for Reproductive Health, 250012, Jinan, Shandong, China.; Shandong Provincial Clinical Research Center for Reproductive Health, 250012, Jinan, Shandong, China.; Shandong Key Laboratory of Reproductive Medicine, Shandong Provincial Hospital Affiliated to Shandong First Medical University, 250012, Jinan, Shandong, China.; Research Unit of Gametogenesis and Health of ART-Offspring, Chinese Academy of Medical Sciences (No.2021RU001), 250012, Jinan, Shandong, China., Yang B; Institute of Women, Children and Reproductive Health, Shandong University, 250012, Jinan, China.; State Key Laboratory of Reproductive Medicine and Offspring Health, Shandong University, 250012, Jinan, Shandong, China.; National Research Center for Assisted Reproductive Technology and Reproductive Genetics, Shandong University, 250012, Jinan, Shandong, China.; Key Laboratory of Reproductive Endocrinology (Shandong University), of Ministry of Education, Shandong University, 250012, Jinan, Shandong, China.; Shandong Technology Innovation Center for Reproductive Health, 250012, Jinan, Shandong, China.; Shandong Provincial Clinical Research Center for Reproductive Health, 250012, Jinan, Shandong, China.; Shandong Key Laboratory of Reproductive Medicine, Shandong Provincial Hospital Affiliated to Shandong First Medical University, 250012, Jinan, Shandong, China.; Research Unit of Gametogenesis and Health of ART-Offspring, Chinese Academy of Medical Sciences (No.2021RU001), 250012, Jinan, Shandong, China., Hou Z; Institute of Women, Children and Reproductive Health, Shandong University, 250012, Jinan, China.; State Key Laboratory of Reproductive Medicine and Offspring Health, Shandong University, 250012, Jinan, Shandong, China.; National Research Center for Assisted Reproductive Technology and Reproductive Genetics, Shandong University, 250012, Jinan, Shandong, China.; Key Laboratory of Reproductive Endocrinology (Shandong University), of Ministry of Education, Shandong University, 250012, Jinan, Shandong, China.; Shandong Technology Innovation Center for Reproductive Health, 250012, Jinan, Shandong, China.; Shandong Provincial Clinical Research Center for Reproductive Health, 250012, Jinan, Shandong, China.; Shandong Key Laboratory of Reproductive Medicine, Shandong Provincial Hospital Affiliated to Shandong First Medical University, 250012, Jinan, Shandong, China.; Research Unit of Gametogenesis and Health of ART-Offspring, Chinese Academy of Medical Sciences (No.2021RU001), 250012, Jinan, Shandong, China., Zhang M; Institute of Women, Children and Reproductive Health, Shandong University, 250012, Jinan, China.; State Key Laboratory of Reproductive Medicine and Offspring Health, Shandong University, 250012, Jinan, Shandong, China.; National Research Center for Assisted Reproductive Technology and Reproductive Genetics, Shandong University, 250012, Jinan, Shandong, China.; Key Laboratory of Reproductive Endocrinology (Shandong University), of Ministry of Education, Shandong University, 250012, Jinan, Shandong, China.; Shandong Technology Innovation Center for Reproductive Health, 250012, Jinan, Shandong, China.; Shandong Provincial Clinical Research Center for Reproductive Health, 250012, Jinan, Shandong, China.; Shandong Key Laboratory of Reproductive Medicine, Shandong Provincial Hospital Affiliated to Shandong First Medical University, 250012, Jinan, Shandong, China.; Research Unit of Gametogenesis and Health of ART-Offspring, Chinese Academy of Medical Sciences (No.2021RU001), 250012, Jinan, Shandong, China., Su W; Institute of Women, Children and Reproductive Health, Shandong University, 250012, Jinan, China.; State Key Laboratory of Reproductive Medicine and Offspring Health, Shandong University, 250012, Jinan, Shandong, China.; National Research Center for Assisted Reproductive Technology and Reproductive Genetics, Shandong University, 250012, Jinan, Shandong, China.; Key Laboratory of Reproductive Endocrinology (Shandong University), of Ministry of Education, Shandong University, 250012, Jinan, Shandong, China.; Shandong Technology Innovation Center for Reproductive Health, 250012, Jinan, Shandong, China.; Shandong Provincial Clinical Research Center for Reproductive Health, 250012, Jinan, Shandong, China.; Shandong Key Laboratory of Reproductive Medicine, Shandong Provincial Hospital Affiliated to Shandong First Medical University, 250012, Jinan, Shandong, China.; Research Unit of Gametogenesis and Health of ART-Offspring, Chinese Academy of Medical Sciences (No.2021RU001), 250012, Jinan, Shandong, China., Chen T; Department of Reproductive Medicine, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China., Bian Y; Institute of Women, Children and Reproductive Health, Shandong University, 250012, Jinan, China.; State Key Laboratory of Reproductive Medicine and Offspring Health, Shandong University, 250012, Jinan, Shandong, China.; National Research Center for Assisted Reproductive Technology and Reproductive Genetics, Shandong University, 250012, Jinan, Shandong, China.; Key Laboratory of Reproductive Endocrinology (Shandong University), of Ministry of Education, Shandong University, 250012, Jinan, Shandong, China.; Shandong Technology Innovation Center for Reproductive Health, 250012, Jinan, Shandong, China.; Shandong Provincial Clinical Research Center for Reproductive Health, 250012, Jinan, Shandong, China.; Shandong Key Laboratory of Reproductive Medicine, Shandong Provincial Hospital Affiliated to Shandong First Medical University, 250012, Jinan, Shandong, China.; Research Unit of Gametogenesis and Health of ART-Offspring, Chinese Academy of Medical Sciences (No.2021RU001), 250012, Jinan, Shandong, China., Li M; Institute of Women, Children and Reproductive Health, Shandong University, 250012, Jinan, China.; State Key Laboratory of Reproductive Medicine and Offspring Health, Shandong University, 250012, Jinan, Shandong, China.; National Research Center for Assisted Reproductive Technology and Reproductive Genetics, Shandong University, 250012, Jinan, Shandong, China.; Key Laboratory of Reproductive Endocrinology (Shandong University), of Ministry of Education, Shandong University, 250012, Jinan, Shandong, China.; Shandong Technology Innovation Center for Reproductive Health, 250012, Jinan, Shandong, China.; Shandong Provincial Clinical Research Center for Reproductive Health, 250012, Jinan, Shandong, China.; Shandong Key Laboratory of Reproductive Medicine, Shandong Provincial Hospital Affiliated to Shandong First Medical University, 250012, Jinan, Shandong, China.; Research Unit of Gametogenesis and Health of ART-Offspring, Chinese Academy of Medical Sciences (No.2021RU001), 250012, Jinan, Shandong, China., Chen ZJ; Institute of Women, Children and Reproductive Health, Shandong University, 250012, Jinan, China.; State Key Laboratory of Reproductive Medicine and Offspring Health, Shandong University, 250012, Jinan, Shandong, China.; National Research Center for Assisted Reproductive Technology and Reproductive Genetics, Shandong University, 250012, Jinan, Shandong, China.; Key Laboratory of Reproductive Endocrinology (Shandong University), of Ministry of Education, Shandong University, 250012, Jinan, Shandong, China.; Shandong Technology Innovation Center for Reproductive Health, 250012, Jinan, Shandong, China.; Shandong Provincial Clinical Research Center for Reproductive Health, 250012, Jinan, Shandong, China.; Shandong Key Laboratory of Reproductive Medicine, Shandong Provincial Hospital Affiliated to Shandong First Medical University, 250012, Jinan, Shandong, China.; Research Unit of Gametogenesis and Health of ART-Offspring, Chinese Academy of Medical Sciences (No.2021RU001), 250012, Jinan, Shandong, China.; Department of Reproductive Medicine, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics, Shanghai, China., Zhao H; Institute of Women, Children and Reproductive Health, Shandong University, 250012, Jinan, China.; State Key Laboratory of Reproductive Medicine and Offspring Health, Shandong University, 250012, Jinan, Shandong, China.; National Research Center for Assisted Reproductive Technology and Reproductive Genetics, Shandong University, 250012, Jinan, Shandong, China.; Key Laboratory of Reproductive Endocrinology (Shandong University), of Ministry of Education, Shandong University, 250012, Jinan, Shandong, China.; Shandong Technology Innovation Center for Reproductive Health, 250012, Jinan, Shandong, China.; Shandong Provincial Clinical Research Center for Reproductive Health, 250012, Jinan, Shandong, China.; Shandong Key Laboratory of Reproductive Medicine, Shandong Provincial Hospital Affiliated to Shandong First Medical University, 250012, Jinan, Shandong, China.; Research Unit of Gametogenesis and Health of ART-Offspring, Chinese Academy of Medical Sciences (No.2021RU001), 250012, Jinan, Shandong, China., Zhao S; Institute of Women, Children and Reproductive Health, Shandong University, 250012, Jinan, China. zsg0108@sdu.edu.cn.; State Key Laboratory of Reproductive Medicine and Offspring Health, Shandong University, 250012, Jinan, Shandong, China. zsg0108@sdu.edu.cn.; National Research Center for Assisted Reproductive Technology and Reproductive Genetics, Shandong University, 250012, Jinan, Shandong, China. zsg0108@sdu.edu.cn.; Key Laboratory of Reproductive Endocrinology (Shandong University), of Ministry of Education, Shandong University, 250012, Jinan, Shandong, China. zsg0108@sdu.edu.cn.; Shandong Technology Innovation Center for Reproductive Health, 250012, Jinan, Shandong, China. zsg0108@sdu.edu.cn.; Shandong Provincial Clinical Research Center for Reproductive Health, 250012, Jinan, Shandong, China. zsg0108@sdu.edu.cn.; Shandong Key Laboratory of Reproductive Medicine, Shandong Provincial Hospital Affiliated to Shandong First Medical University, 250012, Jinan, Shandong, China. zsg0108@sdu.edu.cn.; Research Unit of Gametogenesis and Health of ART-Offspring, Chinese Academy of Medical Sciences (No.2021RU001), 250012, Jinan, Shandong, China. zsg0108@sdu.edu.cn., Wu K; Institute of Women, Children and Reproductive Health, Shandong University, 250012, Jinan, China. wukeliang@sdu.edu.cn.; State Key Laboratory of Reproductive Medicine and Offspring Health, Shandong University, 250012, Jinan, Shandong, China. wukeliang@sdu.edu.cn.; National Research Center for Assisted Reproductive Technology and Reproductive Genetics, Shandong University, 250012, Jinan, Shandong, China. wukeliang@sdu.edu.cn.; Key Laboratory of Reproductive Endocrinology (Shandong University), of Ministry of Education, Shandong University, 250012, Jinan, Shandong, China. wukeliang@sdu.edu.cn.; Shandong Technology Innovation Center for Reproductive Health, 250012, Jinan, Shandong, China. wukeliang@sdu.edu.cn.; Shandong Provincial Clinical Research Center for Reproductive Health, 250012, Jinan, Shandong, China. wukeliang@sdu.edu.cn.; Shandong Key Laboratory of Reproductive Medicine, Shandong Provincial Hospital Affiliated to Shandong First Medical University, 250012, Jinan, Shandong, China. wukeliang@sdu.edu.cn.; Research Unit of Gametogenesis and Health of ART-Offspring, Chinese Academy of Medical Sciences (No.2021RU001), 250012, Jinan, Shandong, China. wukeliang@sdu.edu.cn.
Publikováno v:
EMBO reports [EMBO Rep] 2024 Nov; Vol. 25 (11), pp. 4876-4897. Date of Electronic Publication: 2024 Oct 02.