Zobrazeno 1 - 10
of 1 219
pro vyhledávání: '"CHE Yang"'
Autor:
Sailan Shui, Pablo Gainza, Leo Scheller, Che Yang, Yoichi Kurumida, Stéphane Rosset, Sandrine Georgeon, Raphaël B. Di Roberto, Rocío Castellanos-Rueda, Sai T. Reddy, Bruno E. Correia
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Small-molecule responsive protein switches are crucial components to control synthetic cellular activities. Here, we present a computational protein design strategy to repurpose drug-inhibited protein-protein interactions into OFF- and ON-switches ac
Externí odkaz:
https://doaj.org/article/abf45e9fa38440d9ad04bb724c9f71ce
Autor:
Surbhi Jain, Saurabh Shukla, Che Yang, Meng Zhang, Zia Fatma, Manasi Lingamaneni, Shireen Abesteh, Stephan Thomas Lane, Xiong Xiong, Yuchuan Wang, Charles M. Schroeder, Paul R. Selvin, Huimin Zhao
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
While Cas9 outperforms TALENs in euchromatin, it is less efficient in heterochromatic regions. Here the authors, using single-molecule imaging, show that Cas9 uses a less efficient search strategy compared to TALENs in these regions.
Externí odkaz:
https://doaj.org/article/6c3cb81693a24a32a018bf1763f7bcf5
Autor:
Lei Yu, Shao Thing Teoh, Elliot Ensink, Martin P. Ogrodzinski, Che Yang, Ana I. Vazquez, Sophia Y. Lunt
Publikováno v:
Cancer & Metabolism, Vol 7, Iss 1, Pp 1-13 (2019)
Abstract Background Pancreatic ductal adenocarcinoma (PDAC) is an aggressive cancer with limited treatment options. Pyruvate kinase, especially the M2 isoform (PKM2), is highly expressed in PDAC cells, but its role in pancreatic cancer remains contro
Externí odkaz:
https://doaj.org/article/0dd57d2ce6dc48dd85df26dd36c615c7
Autor:
Kristina M. Geiger, Daniel Guignard, Che Yang, Jean-Pierre Bikorimana, Bruno E. Correia, Sophie Houard, Catherine Mkindi, Claudia A. Daubenberger, François Spertini, Giampietro Corradin, Régine Audran
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
P27A is a novel synthetic malaria vaccine candidate derived from the blood stage Plasmodium falciparum protein Trophozoite Exported Protein 1 (TEX1/PFF0165c). In phase 1a/1b clinical trials in malaria unexposed adults in Switzerland and in malaria pr
Externí odkaz:
https://doaj.org/article/8aa2e3adbc2a4cbca7e1e48344279cbc
Autor:
Fabian Sesterhenn, Marie Galloux, Sabrina S Vollers, Lucia Csepregi, Che Yang, Delphyne Descamps, Jaume Bonet, Simon Friedensohn, Pablo Gainza, Patricia Corthésy, Man Chen, Stéphane Rosset, Marie-Anne Rameix-Welti, Jean-François Éléouët, Sai T Reddy, Barney S Graham, Sabine Riffault, Bruno E Correia
Publikováno v:
PLoS Biology, Vol 17, Iss 2, p e3000164 (2019)
Throughout the last several decades, vaccination has been key to prevent and eradicate infectious diseases. However, many pathogens (e.g., respiratory syncytial virus [RSV], influenza, dengue, and others) have resisted vaccine development efforts, la
Externí odkaz:
https://doaj.org/article/bea6dfa8a79f40869e4c2d0a5963a80d
Autor:
Jaume Bonet, Sarah Wehrle, Karen Schriever, Che Yang, Anne Billet, Fabian Sesterhenn, Andreas Scheck, Freyr Sverrisson, Barbora Veselkova, Sabrina Vollers, Roxanne Lourman, Mélanie Villard, Stéphane Rosset, Thomas Krey, Bruno E Correia
Publikováno v:
PLoS Computational Biology, Vol 14, Iss 11, p e1006623 (2018)
The robust computational design of functional proteins has the potential to deeply impact translational research and broaden our understanding of the determinants of protein function and stability. The low success rates of computational design protoc
Externí odkaz:
https://doaj.org/article/8517291b5c1840df9fd16f03250fc1bc
Autor:
Nien‐Che Yang, Chih‐Hsiung Tseng
Publikováno v:
IET Generation, Transmission & Distribution, Vol 18, Iss 13, Pp 2339-2352 (2024)
Abstract This study introduces a series of strategies to enhance convergence in the Newton–Raphson power flow method for unbalanced distribution networks. The proposed approach incorporates graph theory, Kron reduction, and current injection techni
Externí odkaz:
https://doaj.org/article/8d4aa257b91b45029ed57278f8dc62d0
Publikováno v:
Biodiversity Data Journal, Vol 12, Iss , Pp 1-12 (2024)
Sciaenidae is one of the most important coastal fisheries in Taiwan, both in production and economic value. It is also significant as the main targetted diet of Chinese white dolphins, Sousa chinensis, especially for the genus Johnius, such as J. tai
Externí odkaz:
https://doaj.org/article/5474db2049f14f138a3cffbeb145c7c5
Autor:
En-Che Yang, Yu-Tung Tsai, Po-Ya Chang, Mykhaylo Ozerov, Jurek Krzystek, Su-Ying Chien, Jun-Xian He, Ting-Shen Kuo, Hwo-Shuenn Sheu
Publikováno v:
ACS Omega, Vol 9, Iss 24, Pp 26149-26158 (2024)
Externí odkaz:
https://doaj.org/article/4fb52ac1ca5f481ba4e5c702e7d8d063
Autor:
Ting-Wei Wang, MD, PhD, Yu-Chieh Shiao, MD, Jia-Sheng Hong, PhD, Wei-Kai Lee, PhD, Ming-Sheng Hsu, MD, Hao-Min Cheng, MD, PhD, Huai-Che Yang, MD, PhD, Cheng-Chia Lee, MD, PhD, Hung-Chuan Pan, MD, PhD, Weir Chiang You, MD, PhD, Jiing-Feng Lirng, MD, Wan-Yuo Guo, MD, PhD, Yu-Te Wu, PhD
Publikováno v:
Mayo Clinic Proceedings: Digital Health, Vol 2, Iss 1, Pp 75-91 (2024)
Objective: To thoroughly analyze factors affecting the generalization ability of deep learning algorithms on brain tumor detection and segmentation models. Patients and Methods: We searched PubMed, Embase, Web of Science, Cochrane Library, and IEEE f
Externí odkaz:
https://doaj.org/article/d410f72afc2e48e4be8ed40bb9aeff70