Zobrazeno 1 - 10
of 85
pro vyhledávání: '"CHB, chronic hepatitis B"'
Publikováno v:
Frontiers in Gastroenterology, Vol 3 (2024)
Background and aimsChronic hepatitis B (CHB) and non-alcoholic fatty liver disease (NAFLD) are leading causes of liver-related morbidity and mortality. The interaction between these two disease processes is poorly defined and the impact of NAFLD on H
Externí odkaz:
https://doaj.org/article/8dab092abcaa43bba659aeea37cb9876
Autor:
Haibing Gao, Xiangmei Wang, Huaxi Ma, Shenglong Lin, Dongqing Zhang, Wenjun Wu, Ziyuan Liao, Mengyun Chen, Qin Li, Minghua Lin, Dongliang Li
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
The role of genetic factors in the occurrence and progression of CHB (CHB) is still not fully explored. In recent years, genome-wide association studies on CHB patients have demonstrated that a large number of CHB-associated single nucleotide polymor
Externí odkaz:
https://doaj.org/article/a6b21caa7c0542c5814c99d35e850396
Autor:
Iñaki F. Trocóniz, Juan Jose Perez-Ruixo, Xavier Woot de Trixhe, Eduardo Asín-Prieto, Kim Stuyckens, Zinnia P. Parra-Guillen, José David Gómez Mantilla, Joris Vandenbossche
Publikováno v:
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 4997-5007 (2021)
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 4997-5007 (2021)
Graphical abstract
Highlights • Mechanistic model characterizing acute immune response and HBV system interactions. • Key role of the cellular and regulatory response triggering hepatitis B chronicity. • Modelling framework to easily incor
Highlights • Mechanistic model characterizing acute immune response and HBV system interactions. • Key role of the cellular and regulatory response triggering hepatitis B chronicity. • Modelling framework to easily incor
Autor:
Masaaki Shiina, Masatoshi Ishigami, Takanori Ito, Teiji Kuzuya, Asuka Kato, Norie Yamada, Takanobu Kato, Tetsuya Ishikawa, Masamichi Muramatsu, Mitsuhiro Fujishiro, Tomohisa Tanaka, Kohji Moriishi, Yoji Ishizu, Yoshiki Murakami, Hussein H. Aly, Hironori Nishitsuji, Kunitada Shimotohno, Asako Murayama, Takaji Wakita, Takashi Honda
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 5, Pp 1583-1598 (2021)
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 5, Pp 1583-1598 (2021)
Background & Aims To provide an adequate treatment strategy for chronic hepatitis B, it is essential to know which patients are expected to have a good prognosis and which patients do not require therapeutic intervention. Previously, we identified th
Publikováno v:
JHEP Reports, Vol 4, Iss 2, Pp 100398-(2022)
JHEP Reports
JHEP Reports
Summary: Insights into the immunopathogenesis of chronic HBV infections are fundamental in the quest for novel treatment approaches aimed at a functional cure. While much is known about the ineffective HBV-specific T-cell responses that characterise
Akademický článek
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Autor:
Harry L.A. Janssen, Laurens A. van Kleef, Bettina E. Hansen, Keyur Patel, Willem P. Brouwer, Robert A. de Man, Hannah S.J. Choi, Robert J. de Knegt, Milan J. Sonneveld
Publikováno v:
JHEP Reports, Vol 3, Iss 5, Pp 100350-(2021)
JHEP Reports
JHEP Reports, 3(5):100350. Elsevier
JHEP Reports
JHEP Reports, 3(5):100350. Elsevier
Background & Aims A recent consensus document has defined metabolic dysfunction-associated fatty liver disease (MAFLD) as hepatic steatosis together with overweight, diabetes, and/or a combination of other metabolic risk factors. The clinical relevan
Autor:
Shu Chun Chuang, I-Chien Wu, Tsung-Lung Tsai, Li-Ming Lien, Wen-Hao Huang, Chao A. Hsiung, Ming-Shiang Wu, Yen-Feng Chiu, Chang-Hua Chen, Tieh-Chi Chung, Chung-Chou Juan, Chih-Cheng Hsu, Yen-Tze Liu, Yu-Wen Yang, Wei-Lin Huang
Publikováno v:
Preventive Medicine Reports, Vol 23, Iss, Pp 101432-(2021)
Preventive Medicine Reports
Preventive Medicine Reports
Highlights • More patients with chronic hepatitis B (CHB) are surviving into old age. • The late-life health-related quality of life (HRQoL) they might experience remains unclear. • We repeatedly assessed HRQoL in a cohort of older adults with
Autor:
George V. Papatheodoridis, Harry L.A. Janssen, Florian van Boemmel, Margarita Papatheodoridi, Anastasia Kourikou, Cihan Yurdaydin, Bettina E. Hansen, Pietro Lampertico, John Vlachogiannakos, Ramazan Idilman, Savvoula Savvidou, John Goulis, Marta López-Gómez, Spilios Manolakopoulos, Thomas Berg, Nikolaos K. Gatselis, Maria Buti, Jose Luis Calleja, Rafael Esteban, George N Dalekos, Rhea Veelken, Vana Sypsa, Kostas Galanis, Alessandro Loglio
Publikováno v:
JHEP Reports
JHEP Reports, Vol 3, Iss 3, Pp 100290-(2021)
Scientia
JHEP Reports, 3(3):100290. Elsevier
JHEP Reports, Vol 3, Iss 3, Pp 100290-(2021)
Scientia
JHEP Reports, 3(3):100290. Elsevier
Background & Aims Recently, several risk scores for prediction of hepatocellular carcinoma (HCC) were developed in cohorts of treated Asian patients with chronic hepatitis B (CHB), but they have not been assessed in non-Asian patients. We evaluated t
Publikováno v:
JHEP Reports
JHEP Reports, Vol 3, Iss 4, Pp 100295-(2021)
JHEP Reports, Vol 3, Iss 4, Pp 100295-(2021)
Background & Aims Current standard-of-care suppresses HBV replication, but does not lead to a functional cure. Treatment aiming to cure chronic hepatitis B (CHB) is believed to require the induction of strong cellular immune responses, such as by the