Zobrazeno 1 - 10
of 59
pro vyhledávání: '"CHARLES R HATT"'
Autor:
Sundaresh Ram, Benjamin A Hoff, Alexander J Bell, Stefanie Galban, Aleksa B Fortuna, Oliver Weinheimer, Mark O Wielpütz, Terry E Robinson, Beverley Newman, Dharshan Vummidi, Aamer Chughtai, Ella A Kazerooni, Timothy D Johnson, MeiLan K Han, Charles R Hatt, Craig J Galban
Publikováno v:
PLoS ONE, Vol 16, Iss 3, p e0248902 (2021)
BackgroundRadiologic evidence of air trapping (AT) on expiratory computed tomography (CT) scans is associated with early pulmonary dysfunction in patients with cystic fibrosis (CF). However, standard techniques for quantitative assessment of AT are h
Externí odkaz:
https://doaj.org/article/7bdca52d398445798eb22bb77e7b08be
Autor:
Alexander J. Bell, Ravi Pal, Wassim W. Labaki, Benjamin A. Hoff, Jennifer M. Wang, Susan Murray, Ella A. Kazerooni, Stefanie Galban, David A. Lynch, Stephen M. Humphries, Fernando J. Martinez, Charles R. Hatt, MeiLan K. Han, Sundaresh Ram, Craig J. Galban
Publikováno v:
Respiratory Research, Vol 25, Iss 1, Pp 1-12 (2024)
Abstract Background Small airways disease (SAD) is a major cause of airflow obstruction in COPD patients and has been identified as a precursor to emphysema. Although the amount of SAD in the lungs can be quantified using our Parametric Response Mapp
Externí odkaz:
https://doaj.org/article/7ce7ea7e78a94cbabe467d5df815a259
Autor:
Katherine J. Carey, Peter Hotvedt, David G. Mummy, Kristine E. Lee, Loren C. Denlinger, Mark L. Schiebler, Ronald L. Sorkness, Nizar N. Jarjour, Charles R. Hatt, Craig J. Galban, Sean B. Fain
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Purpose: The purpose of this study was to anatomically correlate ventilation defects with regions of air trapping by whole lung, lung lobe, and airway segment in the context of airway mucus plugging in asthma.Methods: A total of 34 asthmatics [13M:21
Externí odkaz:
https://doaj.org/article/113a354c8fa14727b192ab7f6ef47bdf
Autor:
Sundaresh Ram, Wenfei Tang, Alexander J. Bell, Ravi Pal, Cara Spencer, Alexander Buschhaus, Charles R. Hatt, Marina Pasca diMagliano, Alnawaz Rehemtulla, Jeffrey J. Rodríguez, Stefanie Galban, Craig J. Galban
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 42, Iss , Pp 100911- (2023)
Early detection of lung cancer is critical for improvement of patient survival. To address the clinical need for efficacious treatments, genetically engineered mouse models (GEMM) have become integral in identifying and evaluating the molecular under
Externí odkaz:
https://doaj.org/article/460f7e89aaaa4281be99afd45042a8d2
Autor:
Rachel N. Criner, Charles R. Hatt, Craig J. Galbán, Ella A. Kazerooni, David A. Lynch, Meredith C. McCormack, Richard Casaburi, Neil R. MacIntyre, Barry J. Make, Fernando J. Martinez, Wassim W. Labaki, Jeffrey L. Curtis, Mei Lan K. Han
Publikováno v:
Respiratory Research, Vol 20, Iss 1, Pp 1-4 (2019)
Abstract Impaired single breath carbon monoxide diffusing capacity (DLCO) is associated with emphysema. Small airways disease (SAD) may be a precursor lesion to emphysema, but the relationship between SAD and DLCO is undescribed. We hypothesized that
Externí odkaz:
https://doaj.org/article/70678307387b473fbbcf44b57590ae50
Autor:
Sundaresh Ram, Stijn E. Verleden, Alexander J. Bell, Benjamin A. Hoff, Wassim W. Labaki, Susan Murray, Bart M. Vanaudenaerde, Robin Vos, Geert M. Verleden, Ella A. Kazerooni, Stefanie Galbán, Charles R. Hatt, Meilan K. Han, Vibha N. Lama, Craig J. Galbán
Publikováno v:
Cells, Vol 11, Iss 4, p 699 (2022)
Chronic rejection of lung allografts has two major subtypes, bronchiolitis obliterans syndrome (BOS) and restrictive allograft syndrome (RAS), which present radiologically either as air trapping with small airways disease or with persistent pleuropar
Externí odkaz:
https://doaj.org/article/76c0d4e841aa4f1fae91f3f061539207
Autor:
Zhangxing, Bian, Jiayang, Zhong, Jeffrey, Dominic, Gary E, Christensen, Charles R, Hatt, Nicholas S, Burris
Publikováno v:
Medical Physics. 49:2514-2530
Accurate assessment of thoracic aortic aneurysm (TAA) growth is important for appropriate clinical management. Maximal aortic diameter is the primary metric that is used to assess growth, but it suffers from substantial measurement variability. A rec
Autor:
Jianyang Zhong, Gary E. Christensen, Nicholas S. Burris, Zhangxing Bian, Theodorus M. J. van Bakel, Brian D. Ross, Charles R. Hatt, Jeffrey Dominic, Himanshu J. Patel, Ignas B Houben
Publikováno v:
Radiology. 302(1)
Background Aortic diameter measurements in patients with a thoracic aortic aneurysm (TAA) show wide variation. There is no technique to quantify aortic growth in a three-dimensional (3D) manner. Purpose To validate a CT-based technique for quantifica
Autor:
Susan Murray, Catherine A. Meldrum, MeiLan K. Han, Lauren A. Keith, Craig J. Galbán, Douglas A. Arenberg, Ella A. Kazerooni, Wassim W. Labaki, Abdullah Al-abcha, Meng Xia, Fernando J. Martinez, Jeffrey L. Curtis, Charles R. Hatt, M. Ferrera
Publikováno v:
Chest. 159:1812-1820
Background Lung cancer risk prediction models do not routinely incorporate imaging metrics available on low-dose CT (LDCT) imaging of the chest ordered for lung cancer screening. Research Question What is the association between quantitative emphysem
Autor:
E.K. Silverman, MeiLan K. Han, Craig J. Galbán, Barry J. Make, Elisabeth A Regan, James D. Crapo, Jean-Paul Charbonnier, Steven M Humphries, COPDGene Investigators, David A. Lynch, Matthew Strand, Camille M. Moore, Pim A. de Jong, George R. Washko, Jan-Willem J. Lammers, Firdaus A. A. Mohamed Hoesein, Charles R. Hatt, Esther Pompe, Eva M. van Rikxoort
Publikováno v:
Chronic Obstr Pulm Dis
Chronic Obstructive Pulmonary Diseases : Journal of the COPD Foundation, 8, 2, pp. 198-212
Chronic Obstructive Pulmonary Diseases. Journal of the Copd Foundation, 8, 198-212
Chronic Obstructive Pulmonary Diseases : Journal of the COPD Foundation, 8, 2, pp. 198-212
Chronic Obstructive Pulmonary Diseases. Journal of the Copd Foundation, 8, 198-212
Background: Little is known about factors associated with emphysema progression in cigarette smokers. We evaluated factors associated with change in emphysema and forced expiratory volume in 1 second (FEV(1)) in participants with and without chronic