Zobrazeno 1 - 10
of 240
pro vyhledávání: '"CHARLES, IG"'
Autor:
Yasir M, Turner AK, Bastkowski S, Baker D, Page AJ, Telatin A, Phan M-D, Monahan L, Savva GM, Darling A, Webber MA, Charles IG
Understanding the genetic basis for a phenotype is a central goal in biological research. Much has been learnt about bacterial genomes by creating large mutant libraries and looking for conditionally important genes. However, current genome-wide meth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::6713270c5bee905300e67fb9643aa67b
https://hdl.handle.net/10453/142108
https://hdl.handle.net/10453/142108
© 2015 Society for Applied Microbiology and John Wiley & Sons Ltd. Lateral gene transfer (LGT) has been crucial in the evolution of the cholera pathogen, Vibrio cholerae. The two major virulence factors are present on two different mobile genetic el
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::c2cbc9657bd207b3f9ec7b96e1cb1b2f
Autor:
Stamp, AL, Owen, P, El Omari, K, Nichols, CE, Lockyer, M, Lamb, HK, Charles, IG, Hawkins, AR, Stammers, DK
YcbL has been annotated as either a metallo-β-lactamase or glyoxalase II (GLX2), both members of the zinc metallohydrolase superfamily, that contains many enzymes with a diverse range of activities. Here, we report crystallographic and biochemical d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::602a8a7231165f2b62b066215570bf6c
https://europepmc.org/articles/PMC2998724/
https://europepmc.org/articles/PMC2998724/
The crystal structure of Staphylococcus aureus cytidine monophosphate kinase (CMK) in complex with cytidine 50-monophosphate (CMP) has been determined at 2.3 angstrom resolution. The active site reveals novel features when compared with two orthologu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::5c93075ace59d950369ccfa77e7eb67b
https://hdl.handle.net/10453/13384
https://hdl.handle.net/10453/13384
Ion channels gated directly by cyclic nucleotides are required for the transduction of sensory signals in photoreceptor cells and olfactory cells. Cyclic nucleotide-gated (CNG) channels may also be expressed in the central nervous system because part
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::d15ab2e5d073a37518dc0f1e68d9aecc
https://hdl.handle.net/10453/13744
https://hdl.handle.net/10453/13744
Autor:
Khan, SA, Everest, P, Servos, S, Foxwell, N, Zähringer, U, Brade, H, Rietschel, ET, Dougan, G, Charles, IG, Maskell, DJ
Salmonella infections in naturally susceptible mice grow rapidly, with death occurring only after bacterial numbers in vivo have reached a high threshold level, commonly called the lethal load. Despite much speculation, no direct evidence has been av
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::e1f589680e1050aa136100c328e97b7e
https://hdl.handle.net/10453/13279
https://hdl.handle.net/10453/13279
We have identified a highly polymorphic pentanucleotide repeat (CCTTT)n within the 5'-putative promoter region of the human inducible nitric oxide synthase gene (iNOS, NOS2). Using a pair of specific primers derived from the human iNOS gene, we have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::975466a6e8f37fc5693aabc5603e1e28
https://hdl.handle.net/10453/13234
https://hdl.handle.net/10453/13234