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The distinguishing electrical properties of cancer cells

Autor: Elisabetta Di Gregorio, Simone Israel, Michael Staelens, Gabriella Tankel, Karthik Shankar, Jack A. Tuszyński

Publikováno v: Physics of Life Reviews. 43:139-188

In recent decades, medical research has been primarily focused on the inherited aspect of cancers, despite the reality that only 5-10% of tumours discovered are derived from genetic causes. Cancer is a broad term, and therefore it is inaccurate to ad

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::566bc313f93c58871547f51a98e82ba3
https://doi.org/10.1016/j.plrev.2022.09.003

A recurrent KCNQ2 pore mutation causing early onset epileptic encephalopathy has a moderate effect on M current but alters subcellular localization of Kv7 channels

Autor: Affef Abidi, Jérôme J. Devaux, Florence Molinari, Gisèle Alcaraz, François-Xavier Michon, Julie Sutera-Sardo, Hélène Becq, Caroline Lacoste, Cécilia Altuzarra, Alexandra Afenjar, Cyril Mignot, Diane Doummar, Bertrand Isidor, Sylvie N. Guyen, Estelle Colin, Sabine De La Vaissière, Damien Haye, Adeline Trauffler, Catherine Badens, Fabienne Prieur, Gaetan Lesca, Laurent Villard, Mathieu Milh, Laurent Aniksztejn

Publikováno v: Neurobiology of Disease, Vol 80, Iss , Pp 80-92 (2015)

Mutations in the KCNQ2 gene encoding the voltage-dependent potassium M channel Kv7.2 subunit cause either benign epilepsy or early onset epileptic encephalopathy (EOEE). It has been proposed that the disease severity rests on the inhibitory impact of

Externí odkaz: https://doaj.org/article/bb8812cd369d45d1b82eede26d4f8c12

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Structural and functional remodeling of the atrioventricular node with aging in rats: The role of hyperpolarization-activated cyclic nucleotide–gated and ryanodine 2 channels

Autor: Saeed, Yawer, Temple, Ian, Borbas, Zoltan, Atkinson, Andrew, Yanni Gerges, Joseph, Maczewski, Michał, Mackiewicz, U., Aly, M, Logantha, Sunil, Garratt, Clifford, Dobrzynski, Halina

Publikováno v: Heart Rhythm
Saeed, Y, Temple, I P, Borbas, Z, Atkinson, A, Yanni Gerges, J, Maczewski, M, Mackiewicz, U, Aly, M, Logantha, S, Garratt, C & Dobrzynski, H 2018, ' Structural and functional remodeling of the atrioventricular node with aging in rats: The role of hyperpolarization-activated cyclic nucleotide-gated and ryanodine 2 channels ', Heart Rhythm . https://doi.org/10.1016/j.hrthm.2017.12.027
Saeed, Y, Temple, I, Borbas, Z, Atkinson, A, Yanni Gerges, J, Maczewski, M, Mackiewicz, U, Aly, M, Logantha, S, Garratt, C & Dobrzynski, H 2017, ' Structural and functional remodeling of the atrioventricular node with aging in rats: The role of hyperpolarization-activated cyclic nucleotide-gated and ryanodine 2 channels ' Heart Rhythm . DOI: 10.1016/j.hrthm.2017.12.027

Background Aging is associated with an increased incidence of atrioventricular nodal (AVN) dysfunction. Objective The aim of this study was to investigate the structural and functional remodeling in the atrioventricular junction (AVJ) with aging. Met

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::75488a094cbc5a06658bd10c2a064bd3
http://europepmc.org/articles/PMC5934612