Zobrazeno 1 - 10
of 41
pro vyhledávání: '"CGMP transport"'
Autor:
Aina Westrheim Ravna, Sondre Ulstein Odland, Georg Sager, Erik Sveberg Dietrichs, Natalia Smaglyukova
The biodynamics and biokinetics of sex hormones are complex. In addition to the classical steroid receptors (nuclear receptors), these hormones act through several non-genomic mechanisms. Modulation of ABC-transporters by progesterone represents a no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f222463944499df04f4d813683fb0a4
https://hdl.handle.net/10037/23293
https://hdl.handle.net/10037/23293
Autor:
Farzane Kuresh Kashgari, Erik Sveberg Dietrichs, Georg Sager, Istvan J. Enyedy, Aina Westrheim Ravna, Roy Andre Lyså
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 126, Iss, Pp 110109-(2020)
Background - Clinical studies have reported overexpression of PDE5 and elevation of intracellular cyclic GMP in various types of cancer cells. ABCC5 transports cGMP out of the cells with high affinity. PDE5 inhibitors prevent both cellular metabolism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41c334d1efadc6b2fbc198eb47cbaf3d
https://hdl.handle.net/10037/20662
https://hdl.handle.net/10037/20662
Autor:
Agata H. Bryk, Jacek R. Wiśniewski
Publikováno v:
Journal of Proteome Research
Red blood cells (RBCs) are the most abundant cell type in the human body. RBCs and, in particular, their plasma membrane composition have been extensively studied for many years. During the past decade proteomics studies have extended our knowledge o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e9481981112729141add9dbd4887a15
https://hdl.handle.net/11858/00-001M-0000-002D-E596-411858/00-001M-0000-002D-E598-F11858/00-001M-0000-002D-E599-D11858/00-001M-0000-002D-E59A-B
https://hdl.handle.net/11858/00-001M-0000-002D-E596-411858/00-001M-0000-002D-E598-F11858/00-001M-0000-002D-E599-D11858/00-001M-0000-002D-E59A-B
Publikováno v:
Pharmacology & Pharmacy. :262-271
The acute and chronic effects of sodium nitroprusside (SNP) are well characterized for vascular smooth muscle cells (VSMC). Stimulation of soluble guanylyl cyclase (sGC) gives a rapid elevation of intracellular cGMP levels and relaxation of VSMC. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f59bf653754f5ad4a9368dd5f0cacfa
https://doi.org/10.4236/pp.2014.53033
https://doi.org/10.4236/pp.2014.53033
Publikováno v:
Pharmacology & Pharmacy. :104-109
In the present study we have characterized ATP-dependent transport of cAMP and cGMP in physiological, but also supraphysiological concentrations. The uptake into inside-out vesicles from human erythrocytes could be dissected into two components with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e5c3631e24f50987a8eaf653047dfd2d
https://doi.org/10.4236/pp.2013.41015
https://doi.org/10.4236/pp.2013.41015
Publikováno v:
Journal of Experimental Biology. 211:890-899
SUMMARYGuanosine 3′-5′ cyclic monophosphate (cGMP) and adenosine 3′-5′ cyclic monophosphate (cAMP) are important regulators of cell and tissue function. However, cGMP and cAMP transport have received relatively limited attention, especially i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6776559a3815ac11eafa38c4687dac1
https://doi.org/10.1242/jeb.014837
https://doi.org/10.1242/jeb.014837
Autor:
John D. Schuetz, Peter R. Wielinga, Stefanie L. Hundscheid, Cornelia J. F. de Wolf, Jan Wijnholds, Ingrid van der Heijden, Marcel de Haas, Piet Borst, Nobuhito Ono, George L. Scheffer, Hiroaki Yamaguchi
Publikováno v:
FEBS Journal. 274:439-450
cGMP secretion from cells can be mediated by ATP-binding cassette (ABC) transporters ABCC4, ABCC5, and ABCC11. Indirect evidence suggests that ABCC4 and ABCC5 contribute to cGMP transport by erythrocytes. We have re-investigated the issue using eryth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4fe5e7b545c160b19414025d1fe8f4f
https://doi.org/10.1111/j.1742-4658.2006.05591.x
https://doi.org/10.1111/j.1742-4658.2006.05591.x
Publikováno v:
FEBS Journal. 272:4725-4740
Plant flavonoids are polyphenolic compounds commonly found in vegetables, fruits and many food sources that form a significant portion of our diet. These compounds have been shown to interact with several ATP-Binding Cassette transporters that are li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7493dac87f9f6f2b1743f2a571321e42
https://doi.org/10.1111/j.1742-4658.2005.04888.x
https://doi.org/10.1111/j.1742-4658.2005.04888.x
Autor:
Elena Kosenko, Carmina Montoliu, Miguel A. Serra, José M. Rodrigo, Juan A. del Olmo, Vicente Felipo
Publikováno v:
Liver International. 25:787-795
Background: Cyclic GMP (cGMP) concentration is increased in plasma of patients with liver cirrhosis. Three possible mechanisms may contribute: increased cGMP synthesis by soluble (activated by nitric oxide), or particulate (activated by atrial natriu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a96c427b0798d88458600d62e0cd034
https://doi.org/10.1111/j.1478-3231.2005.01066.x
https://doi.org/10.1111/j.1478-3231.2005.01066.x
Autor:
Rémon A. M. H. Van Aubel, Pascal H. E. Smeets, Frans G. M. Russel, Jeroen J. M. W. van den Heuvel
Publikováno v:
American Journal of Physiology : Renal Physiology, 288, F327-33
American Journal of Physiology : Renal Physiology, 288, 2, pp. F327-33
American Journal of Physiology : Renal Physiology, 288, 2, pp. F327-33
The end product of human purine metabolism is urate, which is produced primarily in the liver and excreted by the kidney through a well-defined basolateral blood-to-cell uptake step. However, the apical cell-to-urine efflux mechanism is as yet uniden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ad1f4e9bb29faca0555a581fecce269
https://doi.org/10.1152/ajprenal.00133.2004
https://doi.org/10.1152/ajprenal.00133.2004