Zobrazeno 1 - 10
of 64
pro vyhledávání: '"CFTR potentiators"'
Autor:
Shiferaw D, Faruqi S
Publikováno v:
Therapeutics and Clinical Risk Management, Vol Volume 15, Pp 1029-1040 (2019)
Dejene Shiferaw,* Shoaib Faruqi*Department of Respiratory Medicine, Hull University Teaching Hospitals NHS Trust, Cottingham HU16 5JQ, UK *These authors contributed equally to this workCorrespondence: Shoaib FaruqiDepartment of Respiratory Medicine,
Externí odkaz:
https://doaj.org/article/a06b69db76014ffdb788ee0d46365df0
Autor:
Giada Righetti, Monica Casale, Michele Tonelli, Nara Liessi, Paola Fossa, Nicoletta Pedemonte, Enrico Millo, Elena Cichero
Publikováno v:
Pharmaceuticals, Vol 13, Iss 12, p 445 (2020)
Cystic fibrosis (CF) is the autosomal recessive disorder most recurrent in Caucasian populations. To combat this disease, many life-prolonging therapies are required and deeply investigated, including the development of the so-called cystic fibrosis
Externí odkaz:
https://doaj.org/article/1e180c37a3f34af1978c5797f69441b3
Autor:
Alyssa Bowling, Alice Eastman, Christian Merlo, Gabrielle Lin, Natalie West, Shivani Patel, Garry Cutting, Neeraj Sharma
Publikováno v:
Journal of Personalized Medicine; Volume 12; Issue 9; Pages: 1448
Genetic variants that introduce premature termination codons (PTCs) have remained difficult to therapeutically target due to lack of protein product. Nonsense mediated mRNA decay (NMD) targets PTC-bearing transcripts to reduce the potentially damagin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d2bb0ed5e0e3cca5876fcaf755e999c
Autor:
Loretta Ferrera, Floriana Cappiello, Maria Rosa Loffredo, Elena Puglisi, Bruno Casciaro, Bruno Botta, Luis J. V. Galietta, Mattia Mori, Maria Luisa Mangoni
Publikováno v:
Cellular and Molecular Life Sciences
Mutations in the cystic fibrosis (CF) transmembrane conductance regulator (CFTR) protein lead to persistent lung bacterial infections, mainly due to Pseudomonas aeruginosa, causing loss of respiratory function and finally death of people affected by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c704536a4b200591d863cf6763e7e042
http://hdl.handle.net/11365/1196439
http://hdl.handle.net/11365/1196439
Akademický článek
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Kniha
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Publikováno v:
Journal of Cellular and Molecular Medicine
J. Cell. Mol. Med. 23, 5225-5234 (2019)
J. Cell. Mol. Med. 23, 5225-5234 (2019)
ABCA3 is a phospholipid transporter implicated in pulmonary surfactant homoeostasis and localized at the limiting membrane of lamellar bodies, the storage compartment for surfactant in alveolar type II cells. Mutations in ABCA3 display a common genet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::fc9eb528d9901cb5b9521dc4235f0c38
https://pubmed.ncbi.nlm.nih.gov/31210424
https://pubmed.ncbi.nlm.nih.gov/31210424
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Monica Casale, Enrico Millo, Nara Liessi, Michele Tonelli, Giada Righetti, Paola Fossa, Elena Cichero, Nicoletta Pedemonte
Publikováno v:
Pharmaceuticals
Volume 13
Issue 12
Pharmaceuticals, Vol 13, Iss 445, p 445 (2020)
Volume 13
Issue 12
Pharmaceuticals, Vol 13, Iss 445, p 445 (2020)
Cystic fibrosis (CF) is the autosomal recessive disorder most recurrent in Caucasian populations. To combat this disease, many life-prolonging therapies are required and deeply investigated, including the development of the so-called cystic fibrosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::780fa7d97b687979c05dcd9aeeed91c2
https://doi.org/10.3390/ph13120445
https://doi.org/10.3390/ph13120445
Autor:
Maria Valeria Raimondi, Paola Barraja, Luis J. V. Galietta, Michele Genovese, Virginia Spanò, Alessandra Montalbano, Arianna Venturini, Marilia Barreca
Publikováno v:
European Journal of Medicinal Chemistry. 204:112631
Cystic fibrosis (CF) is a genetic disorder produced by the loss of function of CFTR, a main chloride channel involved in transepithelial salt and water transport. CFTR function can be rescued by small molecules called "potentiators" which increase ga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a38320d3d9c622fa21f2fbe7531ca867
https://doi.org/10.1016/j.ejmech.2020.112631
https://doi.org/10.1016/j.ejmech.2020.112631