Outcomes of children with cystic fibrosis screen positive, inconclusive diagnosis/CFTR related metabolic syndrome

Autor: Mohini A. Gunnett, Elizabeth Baker, Cathy Mims, Staci T. Self, Hector H. Gutierrez, Jennifer S. Guimbellot

Publikováno v: Frontiers in Pediatrics, Vol 11 (2023)

BackgroundSome infants undergoing newborn screening (NBS) tests have inconclusive sweat chloride test (SCT) results that lead to the designation of Cystic Fibrosis Screen Positive, Inconclusive Diagnosis/CFTR-related metabolic syndrome (CFSPID/CRMS).

Externí odkaz: https://doaj.org/article/8035a43de04d4eb3973b919031e6fc56

Allicin Facilitates Airway Surface Liquid Hydration by Activation of CFTR

Autor: Zhuo-Er Qiu, Jian-Bang Xu, Lei Chen, Ze-Xin Huang, Tian-Lun Lei, Zi-Yang Huang, Xiao-Chun Hou, Hai-Long Yang, Qin-Hua Lin, Yun-Xin Zhu, Lei Zhao, Wen-Liang Zhou, Yi-Lin Zhang

Publikováno v: Frontiers in Pharmacology, Vol 13 (2022)

Airway epithelium plays critical roles in regulating airway surface liquid (ASL), the alteration of which causes mucus stasis symptoms. Allicin is a compound released from garlic and harbors the capacity of lung-protection. However, the potential reg

Externí odkaz: https://doaj.org/article/f0ad04e4d82244cbbd3c1030ce836bdc

Editorial: Functional Characterization and Pharmaceutical Targets in Common and Rare CFTR Dysfunctions

Autor: Elena K. Schneider-Futschik, Viola H. Lobert, John W. Wilson

Publikováno v: Frontiers in Physiology, Vol 12 (2022)

Externí odkaz: https://doaj.org/article/b8ca86ef49cd4deb9191b158c911ea35

Nedd4-2–dependent Ubiquitination Potentiates the Inhibition of Human NHE3 by Cholera Toxin and Enteropathogenic Escherichia coli

Autor: C. Chris Yun, Yiran Han, Songbai Lin, Peijian He, Kayte A. Jenkin

Publikováno v: Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 3, Pp 695-716 (2022)
Cellular and Molecular Gastroenterology and Hepatology

Background & Aims Diarrhea is one of the most common illnesses and is often caused by bacterial infection. Recently, we have shown that human Na+/H+ exchanger NHE3 (hNHE3), but not non-human NHE3s, interacts with the E3 ubiquitin ligase Nedd4-2. We h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01d39e72e4258b61df22d22d51d780ec
https://doi.org/10.1016/j.jcmgh.2021.11.006

Patient and family experience of telehealth care delivery as part of the CF chronic care model early in the COVID-19 pandemic

Autor: George M. Solomon, Julianna Bailey, James Lawlor, Peter Scalia, Gregory S. Sawicki, Christopher Dowd, Kathryn A. Sabadosa, Aricca Van Citters

Publikováno v: Journal of Cystic Fibrosis

Background During the COVID-19 pandemic, CF centers shifted to a telehealth delivery model. Our study aimed to determine how people with CF (PwCF) and their families experienced telehealth and assessed its quality and acceptability for future CF care

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::576fe0f2398cfb102550eb8cf103088b
https://doi.org/10.1016/j.jcf.2021.09.005