Zobrazeno 1 - 10
of 29
pro vyhledávání: '"CFSE, carboxyfluorescein succinimidyl ester"'
Publikováno v:
Regenerative Therapy, Vol 19, Iss, Pp 47-57 (2022)
Regenerative Therapy
Regenerative Therapy
Introduction In cartilage regenerative medicine, transplanted chondrocytes contain a mixture of populations, that complicates the regeneration of uniform cartilage tissue. Our group previously reported that chondrocytes with higher chondrogenic abili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c06444b0fa6329b13d361c5bc121fbfe
https://doi.org/10.1016/j.reth.2021.12.005
https://doi.org/10.1016/j.reth.2021.12.005
Autor:
Andreas Zollner, Nicole Przysiecki, Sophie Macheiner, Vera Reinstadler, Barbara Jelusic, Simon J. Reider, Herbert Tilg, Christina Watschinger, Alexandra Pfister, Herbert Oberacher, Alexander R. Moschen, Bernhard Texler
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 2, Pp 383-404 (2022)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Objective By interfering with multiple cytokines, human Janus kinase inhibitors (JAKis) are of growing importance in the treatment of malignant and inflammatory conditions. Although tofacitinib has demonstrated efficacy as the first-in-class JAKi in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf6e0dffe3ffcc5c8d849bd534a91dfc
http://www.sciencedirect.com/science/article/pii/S2352345X21001922
http://www.sciencedirect.com/science/article/pii/S2352345X21001922
Autor:
Rheinallt M. Jones, Bejan Saeedi, Richard U. Eboka, Trevor Darby, Joshua A. Owens, Crystal Naudin, Sarah Hunter-Chang, Maria E. Barbian, Lauren Askew, Brian S. Robinson
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 4, Pp 1311-1327 (2021)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims In colorectal cancer, approximately 95% of patients are refractory to immunotherapy because of low antitumor immune responses. Therefore, there is an exigent need to develop treatments that increase antitumor immune responses and de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8a2842f4bdfc40a2fd1a616f50f932c
https://doi.org/10.1016/j.jcmgh.2021.06.001
https://doi.org/10.1016/j.jcmgh.2021.06.001
Autor:
David L. Caudell, Nancy L. Buechler, Anuj Jailwala, Mark T. Gladwin, Vidula Vachharajani, Hee Won Kim, Daniel B. Kim-Shapiro, Andreas Perlegas, Martha A. Alexander-Miller, Elaheh Rahbar, Nadeem Wajih, Swati Basu, Crystal Bolden, David Ostrowski
Publikováno v:
Redox Biology, Vol 12, Iss, Pp 1026-1039 (2017)
Redox Biology
Redox Biology
Sickle cell disease is caused by a mutant form of hemoglobin that polymerizes under hypoxic conditions, increasing rigidity, fragility, calcium influx-mediated dehydration, and adhesivity of red blood cells. Increased red cell fragility results in he
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2e23db9f12510f732520f69af10d6e1
http://www.sciencedirect.com/science/article/pii/S2213231717302525
http://www.sciencedirect.com/science/article/pii/S2213231717302525
Autor:
Lucie, Colineau, Maisem, Laabei, Guanghui, Liu, David, Ermert, John D, Lambris, Kristian, Riesbeck, Anna M, Blom
Publikováno v:
Matrix Biology Plus
Streptococcus pyogenes is a major human pathogen that causes a variety of diseases ranging from mild skin and throat infections to fatal septicemia. In severe invasive infections, S. pyogenes encounters and interacts with components of the extracellu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e45c0dc4c5ea0674943b69b1fd340b0c
https://pubmed.ncbi.nlm.nih.gov/33543018
https://pubmed.ncbi.nlm.nih.gov/33543018
Autor:
Richard Ouedraogo, HyeMee Joo, Chao Gu, Katherine Upchurch, Yaming Xue, Sangkon Oh, Jean-Pierre Gorvel, Jong R. Kim, Gerard Zurawski, Dorothée Duluc, Zhiqing Wang, Laurent Gorvel, Dapeng Li, Wenjie Yin, Ling Ni, Sandra Zurawski
Publikováno v:
EBioMedicine, Vol 5, Iss C, Pp 46-58 (2016)
EBioMedicine
EBioMedicine, Elsevier, 2016, 5, pp.46-58. ⟨10.1016/j.ebiom.2016.01.029⟩
EBioMedicine, 2016, 5, pp.46-58. ⟨10.1016/j.ebiom.2016.01.029⟩
EBioMedicine
EBioMedicine, Elsevier, 2016, 5, pp.46-58. ⟨10.1016/j.ebiom.2016.01.029⟩
EBioMedicine, 2016, 5, pp.46-58. ⟨10.1016/j.ebiom.2016.01.029⟩
Dendritic cells (DCs) are major antigen-presenting cells that can efficiently prime and cross-prime antigen-specific T cells. Delivering antigen to DCs via surface receptors is thus an appealing strategy to evoke cellular immunity. Nonetheless, which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c5249e37a5e5b50cfbd1b8608609f64
http://www.sciencedirect.com/science/article/pii/S2352396416300263
http://www.sciencedirect.com/science/article/pii/S2352396416300263
Autor:
Cambrian Y. Liu
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 9, Iss 3, Pp 543-544 (2020)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims Integrin α4β7 mediates lymphocyte trafficking to the gut and gut-associated lymphoid tissues, a process critical for recruitment of effector lymphocytes from the circulation to the gut mucosa in inflammatory bowel disease (IBD) an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69f6a47cc1b87e7ca203ff579c4aecca
http://www.sciencedirect.com/science/article/pii/S2352345X19301651
http://www.sciencedirect.com/science/article/pii/S2352345X19301651
Autor:
Peter Crauwels, Susi Krämer, Stefan Tenzer, Rebecca Bohn, Elena Bank, Max Bastian, Ger van Zandbergen, Stefan Gottwalt, Paul Walther, Florian Jäckel, Meike Thomas
Publikováno v:
Autophagy
Apoptosis is a well-defined cellular process in which a cell dies, characterized by cell shrinkage and DNA fragmentation. In parasites like Leishmania, the process of apoptosis-like cell death has been described. Moreover upon infection, the apoptoti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3d4c51b6d0167edde6a36126fbd4617
http://europepmc.org/articles/PMC4502818
http://europepmc.org/articles/PMC4502818
Autor:
Paul, Tuijnenburg, Hana, Lango Allen, Siobhan O, Burns, Daniel, Greene, Machiel H, Jansen, Emily, Staples, Jonathan, Stephens, Keren J, Carss, Daniele, Biasci, Helen, Baxendale, Moira, Thomas, Anita, Chandra, Sorena, Kiani-Alikhan, Hilary J, Longhurst, Suranjith L, Seneviratne, Eric, Oksenhendler, Ilenia, Simeoni, Godelieve J, de Bree, Anton T J, Tool, Ester M M, van Leeuwen, Eduard H T M, Ebberink, Alexander B, Meijer, Salih, Tuna, Deborah, Whitehorn, Matthew, Brown, Ernest, Turro, Adrian J, Thrasher, Kenneth G C, Smith, James E, Thaventhiran, Taco W, Kuijpers, Christopher, Watt
Publikováno v:
The Journal of Allergy and Clinical Immunology
Background The genetic cause of primary immunodeficiency disease (PID) carries prognostic information. Objective We conducted a whole-genome sequencing study assessing a large proportion of the NIHR BioResource–Rare Diseases cohort. Methods In the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::92e6be24bc203e5c4c62a8ddd2bcbd41
https://pubmed.ncbi.nlm.nih.gov/30165054
https://pubmed.ncbi.nlm.nih.gov/30165054
Autor:
King, Andrew, Houlihan, Diarmaid D., Kavanagh, Dean, Haldar, Debashis, Luu, Nguyet, Owen, Andrew, Suresh, Shankar, Than, Nwe Ni, Reynolds, Gary, Penny, Jasmine, Sumption, Henry, Ramachandran, Prakash, Henderson, Neil C., Kalia, Neena, Frampton, Jon, Adams, David H., Newsome, Philip N.
Publikováno v:
King, A, Houlihan, D D, Kavanagh, D, Haldar, D, Luu, N, Owen, A, Suresh, S, Than, N N, Reynolds, G, Penny, J, Sumption, H, Ramachandran, P, Henderson, N C, Kalia, N, Frampton, J, Adams, D H & Newsome, P N 2017, ' Sphingosine-1-phosphate Prevents Egress of Hematopoietic Stem Cells From Liver to Reduce Fibrosis ', Gastroenterology, vol. 153, no. 1, pp. 233-248.e16 . https://doi.org/10.1053/j.gastro.2017.03.022
Gastroenterology
Gastroenterology
BACKGROUND & AIMS: There is growing interest in the use of bone marrow cells to treat liver fibrosis, however little is known about their anti-fibrotic efficacy or the identity of their effector cell(s). Sphingosine-1-phosphate (S1P) mediates egress
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::7c72386080233dac6dbeaa1fc33337a2