Zobrazeno 1 - 10
of 614
pro vyhledávání: '"CFP-10"'
Autor:
Timothy A Bates, Mila Trank-Greene, Xammy Nguyenla, Aidan Anastas, Sintayehu K Gurmessa, Ilaria R Merutka, Shandee D Dixon, Anthony Shumate, Abigail R Groncki, Matthew AH Parson, Jessica R Ingram, Eric Barklis, John E Burke, Ujwal Shinde, Hidde L Ploegh, Fikadu G Tafesse
Publikováno v:
eLife, Vol 12 (2024)
Mycobacterium tuberculosis (Mtb) is known to survive within macrophages by compromising the integrity of the phagosomal compartment in which it resides. This activity primarily relies on the ESX-1 secretion system, predominantly involving the protein
Externí odkaz:
https://doaj.org/article/02546070fb4649659e3251bb6aab7254
Autor:
Dmitry A. Kudlai, N. P. Doktorova
Publikováno v:
Инфекция и иммунитет, Vol 12, Iss 3, Pp 439-449 (2022)
Recombinant technologies have been long widely used in medicine. This article presents a review on the application of medical technologies based on ESAT-6 and CFP-10 proteins in diagnostics and prevention of tuberculosis. ESAT-6 and CFP-10 are specif
Externí odkaz:
https://doaj.org/article/75e4b803bc104b1d935872e0def5304a
Autor:
Jinjie Yu, Xueting Fan, Xiuli Luan, Ruihuan Wang, Bin Cao, Chengyu Qian, Guilian Li, Machao Li, Xiuqin Zhao, Haican Liu, Kanglin Wan, Xiuqin Yuan
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Tuberculosis (TB) is an infectious disease that seriously affects human health. Until now, the only anti-TB vaccine approved for use is the live attenuated Mycobacterium bovis (M. bovis) vaccine — BCG vaccine, but its protective efficacy is relativ
Externí odkaz:
https://doaj.org/article/00b01d1b1da1488b8423119436efd077
Autor:
Qingbo Shu, Meena Rajagopal, Jia Fan, Lingpeng Zhan, Xiangxing Kong, Yifan He, Suwatchareeporn Rotcheewaphan, Christopher J. Lyon, Wei Sha, Adrian M. Zelazny, Tony Hu
Publikováno v:
View, Vol 3, Iss 4, Pp n/a-n/a (2022)
Abstract Pulmonary disease arising from slow‐growing mycobacterial infections has emerged as an increasingly prevalent clinical concern over the past two to three decades. Proteins belonging to the family of ESAT‐6 secretion (Esx) systems play cr
Externí odkaz:
https://doaj.org/article/92cd85f407364ff8aeb89656e766c36f
Autor:
Liyan Mao, Sylvia M. LaCourse, Soyeon Kim, Chang Liu, Bo Ning, Duran Bao, Jia Fan, Christopher J. Lyon, Ziyong Sun, Sharon Nachman, Charles D. Mitchell, Tony Y. Hu
Publikováno v:
BMC Medicine, Vol 19, Iss 1, Pp 1-12 (2021)
Abstract Background Non-sputum methods are urgently needed to improve tuberculosis diagnosis and treatment monitoring in children. This study evaluated the ability of a serum assay quantifying a species-specific peptide of the Mycobacterium tuberculo
Externí odkaz:
https://doaj.org/article/11abb6089acd4ca0a241b4aa76960ff6
Autor:
Elizabeth A García, Federico C Blanco, Ximena Ferrara Muñiz, María E Eirin, Laura Ines Klepp, Fabiana Bigi
Publikováno v:
International Journal of Mycobacteriology, Vol 9, Iss 4, Pp 417-421 (2020)
Background: Bovine tuberculosis (bTB) is a zoonotic disease caused by Mycobacterium bovis that mainly affects cattle. Although vaccination is the most effective strategy to control bTB, it may interfere with the diagnosis of the infection. Therefore,
Externí odkaz:
https://doaj.org/article/9efb821a00e94eddba56d1c0721757ef
Autor:
Palesa Pamela Seele, Busiswa Dyan, Amanda Skepu, Charlotte Maserumule, Nicole Remaliah Samantha Sibuyi
Publikováno v:
Biosensors, Vol 13, Iss 3, p 354 (2023)
The current study reports on the development of a rapid and cost-effective TB-antigen diagnostic test for the detection of Mycobacterium biomarkers from non-sputum-based samples. Two gold nanoparticle (AuNP)-based rapid diagnostic tests (RDTs) in the
Externí odkaz:
https://doaj.org/article/faa9635cbbf544bfac4853e2122caa16
Akademický článek
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Autor:
Charlene Clarke, Tanya J. Kerr, Robin M. Warren, Léanie Kleynhans, Michele A. Miller, Wynand J. Goosen
Publikováno v:
Microorganisms, Vol 10, Iss 9, p 1861 (2022)
Diagnosis of bovine tuberculosis (bTB) may be confounded by immunological cross-reactivity to Mycobacterium bovis antigens when animals are sensitised by certain nontuberculous mycobacteria (NTMs). Therefore, this study aimed to investigate NTM speci
Externí odkaz:
https://doaj.org/article/7f6bd9123d8a4d45a7bc4ac22b82c187
Akademický článek
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