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pro vyhledávání: '"CFH, complement factor H"'
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Akademický článek
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Publikováno v:
Iranian journal of kidney diseases. 13(2)
While terminal complement blockade with Eculizumab is the first line therapy for atypical HUS (Haemolytic uremic syndrome), lack of its availability and cost limits its use. Plasma exchange becomes a first line modality in the current scenario. Howev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9a6aec667c6144434da46d08849b0873
https://pubmed.ncbi.nlm.nih.gov/30988252
https://pubmed.ncbi.nlm.nih.gov/30988252
Autor:
Aydinlou, Zahra Hassanpour1 (AUTHOR), Vaezi, Helaleh1 (AUTHOR), Bonyadi, Mortaza1 (AUTHOR), Rafat, Abbas2 (AUTHOR), Jabbarpoor Bonyadi, Mohammad Hossein3 (AUTHOR) mhbonyadi@yahoo.com, Soheilian, Masoud4 (AUTHOR)
Publikováno v:
Ophthalmic Genetics. Aug2022, Vol. 43 Issue 4, p446-449. 4p.
Publikováno v:
Ophthalmology, 126, 1422-1423
Ophthalmology: Journal of The American Academy of Ophthalmology, 126(10), 1422-1423
Ophthalmology
Ophthalmology, 126(10), 1422-1423. Elsevier Inc.
Ophthalmology, 126, 10, pp. 1422-1423
Ophthalmology: Journal of The American Academy of Ophthalmology, 126(10), 1422-1423
Ophthalmology
Ophthalmology, 126(10), 1422-1423. Elsevier Inc.
Ophthalmology, 126, 10, pp. 1422-1423
Purpose To characterize the molecular mechanism underpinning early-onset macular drusen (EOMD), a phenotypically severe subtype of age-related macular degeneration (AMD), in a subgroup of patients. Design Multicenter case series, in vitro experimenta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40ae99f556fdb3f41c094e17d51c0655
https://doi.org/10.1016/j.ophtha.2019.04.033
https://doi.org/10.1016/j.ophtha.2019.04.033
Autor:
Nawajes A Mandal, Sandip K. Basu, Richard C. Grambergs, Bano Qaladize, M. Victoria Simón, Nora P. Rotstein
Publikováno v:
Journal of Lipid Research, Vol 62, Iss, Pp 100037-(2021)
Journal of Lipid Research
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Journal of Lipid Research
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Sphingolipids have emerged as bioactive lipids involved in the regulation of many physiological and pathological processes. In the retina, they have been established toparticipate in numerousprocesses, suchas neuronal survival and death, proliferatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::639e875fa28547227b078cf550989119
https://doi.org/10.1194/jlr.tr120000972
https://doi.org/10.1194/jlr.tr120000972
Autor:
Mao Nakayama, Subhabrata Chakrabarti, Inderjeet Kaur, Margaret M DeAngelis, Taraprasad Das, Toru Noda, Megumi Yamamoto, Daisuke Iejima, Paul N. Baird, Akiko Suga, Robyn H. Guymer, Takeshi Iwata, Yang Pan
Publikováno v:
The Journal of Biological Chemistry
The disease-initiating molecular events for age-related macular degeneration (AMD), a multifactorial retinal disease affecting many millions of elderly individuals worldwide, are still unknown. Of the over 30 risk and protective loci so far associate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47857712d23c3c53fbf629db43532576
https://doi.org/10.1016/j.jbc.2021.100456
https://doi.org/10.1016/j.jbc.2021.100456
Publikováno v:
Bioscience Reports
aHUS (atypical haemolytic uraemic syndrome), AMD (age-related macular degeneration) and other diseases are associated with defective AP (alternative pathway) regulation. CFH (complement factor H), CFI (complement factor I), MCP (membrane cofactor pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b85f79bcdb8751a8075d9c906916e95d
https://pubmed.ncbi.nlm.nih.gov/25188723
https://pubmed.ncbi.nlm.nih.gov/25188723
Autor:
Weismann, David, Binder, Christoph J.
Publikováno v:
Biochimica et Biophysica Acta
Lipid peroxidation occurs in the context of many physiological processes but is greatly increased in various pathological situations. A consequence of phospholipid peroxidation is the generation of oxidation-specific epitopes, such as phosphocholine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::0d9231e77bdd58b39b47f9d1aef83063
http://europepmc.org/articles/PMC3790971
http://europepmc.org/articles/PMC3790971
Autor:
Alan F. Wright, Valentina Cipriani, David Clayton, Baljinder K Matharu, Humma Shahid, John R.W. Yates, Catey Bunce, Chloe M. Stanton, Caroline Hayward, Anthony T. Moore, Jane C. Khan
Publikováno v:
Immunobiology
Cipriani, V, Matharu, B K, Khan, J C, Shahid, H, Stanton, C M, Hayward, C, Wright, A F, Bunce, C, Clayton, D G, Moore, A T & Yates, J R W 2012, ' Genetic variation in complement regulators and susceptibility to age-related macular degeneration ', Immunobiology, vol. 217, no. 2, pp. 158-61 . https://doi.org/10.1016/j.imbio.2011.09.002
Cipriani, V, Matharu, B K, Khan, J C, Shahid, H, Stanton, C M, Hayward, C, Wright, A F, Bunce, C, Clayton, D G, Moore, A T & Yates, J R W 2012, ' Genetic variation in complement regulators and susceptibility to age-related macular degeneration ', Immunobiology, vol. 217, no. 2, pp. 158-61 . https://doi.org/10.1016/j.imbio.2011.09.002
ObjectivesAge-related macular degeneration (AMD) is the commonest cause of blindness in Western populations. Risk is influenced by age, genetic and environmental factors. Complement activation appears to be important in the pathogenesis and associati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f14efd8e54c79c4ee19bac159303e5c
http://europepmc.org/articles/PMC3657157
http://europepmc.org/articles/PMC3657157